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View Structure Prediction Details

Protein: CDPKO_ARATH
Organism: Arabidopsis thaliana
Length: 582 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CDPKO_ARATH.

Description E-value Query
Range
Subject
Range
gi|26450847 - gi|26450847|dbj|BAC42531.1| putative calcium-dependent protein kinase [Arabidopsis thaliana]
444.0 [0..1] [582..1]

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Predicted Domain #1
Region A:
Residues: [1-380]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSCVSSPLK GSPFGKRPVR RRHSSNSRTS SVPRFDSSTN LSRRLIFQPP SRVLPEPIGD  60
   61 GIHLKYDLGK ELGRGEFGVT HECIEISTRE RFACKRISKE KLRTEIDVED VRREVEIMRC 120
  121 LPKHPNIVSF KEAFEDKDAV YLVMEICEGG ELFDRIVSRG HYTERAAASV AKTILEVVKV 180
  181 CHEHGVIHRD LKPENFLFSN GTETAQLKAI DFGLSIFFKP AQRFNEIVGS PYYMAPEVLR 240
  241 RNYGPEIDVW SAGVILYILL CGVPPFWAET EEGIAHAIVR GNIDFERDPW PKVSHEAKEL 300
  301 VKNMLDANPY SRLTVQEVLE HPWIRNAERA PNVNLGDNVR TKIQQFLLMN RFKKKVLRIV 360
  361 ADNLPNEEIA AIVQMFQTMD 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 73.09691
Match: 1a06A
Description: CALMODULIN-DEPENDENT PROTEIN KINASE FROM RAT
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphotransferase activity, alcohol group as acceptor 5.49988294224815 bayes_pls_golite062009
protein kinase activity 5.4586557943719 bayes_pls_golite062009
kinase activity 5.3287080791198 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.96052051118534 bayes_pls_golite062009
protein serine/threonine kinase activity 4.46381887831481 bayes_pls_golite062009
calmodulin-dependent protein kinase activity 4.31938467136214 bayes_pls_golite062009
transferase activity 3.97138602499442 bayes_pls_golite062009
binding 2.74863538127007 bayes_pls_golite062009
tubulin binding 2.18641675163967 bayes_pls_golite062009
cytoskeletal protein binding 2.12615078788254 bayes_pls_golite062009
ATP binding 1.97600611746091 bayes_pls_golite062009
adenyl ribonucleotide binding 1.93596671856664 bayes_pls_golite062009
adenyl nucleotide binding 1.90928021591891 bayes_pls_golite062009
microtubule binding 1.88110801192607 bayes_pls_golite062009
purine ribonucleotide binding 1.65732943334212 bayes_pls_golite062009
ribonucleotide binding 1.65726906484847 bayes_pls_golite062009
purine nucleotide binding 1.63763394711025 bayes_pls_golite062009
nucleotide binding 1.63195828048121 bayes_pls_golite062009
protein tyrosine kinase activity 1.3898059094397 bayes_pls_golite062009
receptor signaling protein serine/threonine kinase activity 1.38496328649031 bayes_pls_golite062009
actin binding 1.33479685165255 bayes_pls_golite062009
gamma-tubulin binding 1.28511591054866 bayes_pls_golite062009
receptor signaling protein activity 1.27291233344322 bayes_pls_golite062009
protein binding 1.22565748038754 bayes_pls_golite062009
catalytic activity 1.21655087018101 bayes_pls_golite062009
structural constituent of cytoskeleton 0.612883428421652 bayes_pls_golite062009
transporter activity 0.553953601841147 bayes_pls_golite062009
cyclin-dependent protein kinase activity 0.499492353295369 bayes_pls_golite062009
protein serine/threonine/tyrosine kinase activity 0.48345772948903 bayes_pls_golite062009
magnesium ion binding 0.393328812780268 bayes_pls_golite062009
transmembrane transporter activity 0.37676337669549 bayes_pls_golite062009
MAP kinase kinase kinase activity 0.37115026509016 bayes_pls_golite062009
MAP kinase kinase activity 0.35402045013148 bayes_pls_golite062009
signal transducer activity 0.270054246024761 bayes_pls_golite062009
molecular transducer activity 0.270054246024761 bayes_pls_golite062009
actin filament binding 0.2403700250846 bayes_pls_golite062009
MAP kinase activity 0.08504542461349 bayes_pls_golite062009
substrate-specific transporter activity 0.0611721261859464 bayes_pls_golite062009
transmembrane receptor protein kinase activity 0.0556163711947139 bayes_pls_golite062009
transmembrane receptor activity 0.00652065412910241 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [381-455]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TDKNGHLTFE ELRDGLKKIG QVVPDGDVKM LMDAADTDGN GMLSCDEFVT LSIHLKRMGC  60
   61 DEHLQEAFKY FDKNG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.22
Match: 1c7vA
Description: Calcium vector protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytoskeletal protein binding 3.37000471863591 bayes_pls_golite062009
motor activity 3.1249083077713 bayes_pls_golite062009
binding 3.05873877511752 bayes_pls_golite062009
tubulin binding 2.47289019856128 bayes_pls_golite062009
actin binding 2.30442162024267 bayes_pls_golite062009
microtubule binding 2.1489822301796 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.53627323071172 bayes_pls_golite062009
kinase activity 1.5084125760881 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.38167703866348 bayes_pls_golite062009
protein binding 1.09433047543741 bayes_pls_golite062009
transferase activity 1.04568936971207 bayes_pls_golite062009
metal ion binding 0.917729143462208 bayes_pls_golite062009
cation binding 0.917729143462208 bayes_pls_golite062009
ion binding 0.911048755556638 bayes_pls_golite062009
actin filament binding 0.781511660560369 bayes_pls_golite062009
structural molecule activity 0.764402887442781 bayes_pls_golite062009
structural constituent of muscle 0.699876898567343 bayes_pls_golite062009
transporter activity 0.617351974698691 bayes_pls_golite062009
calcium ion binding 0.588882318835794 bayes_pls_golite062009
transcription regulator activity 0.467743512816825 bayes_pls_golite062009
G-protein beta/gamma-subunit binding 0.409076621558761 bayes_pls_golite062009
transmembrane transporter activity 0.368235648596438 bayes_pls_golite062009
nucleic acid binding 0.261594391889186 bayes_pls_golite062009
DNA binding 0.126696463568471 bayes_pls_golite062009
structural constituent of cytoskeleton 0.114682464671044 bayes_pls_golite062009
substrate-specific transporter activity 0.0683555556984989 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [456-582]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGFIELDELK VALCDDKLGH ANGNDQWIKD IFFDVDLNKD GRISFDEFKA MMKSGTDWKM  60
   61 ASRQYSRALL NALSIKMFKE DFGDNGPKSH SMEFPIARKR AKLLDAPKNK SMELQISKTY 120
  121 KPSGLRN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.0
Match: 2aaoA
Description: Regulatory apparatus of Calcium Dependent protein kinase from Arabidopsis thaliana
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle