| Protein: | HDA19_ARATH |
| Organism: | Arabidopsis thaliana |
| Length: | 501 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HDA19_ARATH.
| Description | E-value | Query Range |
Subject Range |
|
|
548.0 | [0..1] | [501..1] |
|
Region A: Residues: [1-381] |
1 11 21 31 41 51
| | | | | |
1 MDTGGNSLAS GPDGVKRKVC YFYDPEVGNY YYGQGHPMKP HRIRMTHALL AHYGLLQHMQ 60
61 VLKPFPARDR DLCRFHADDY VSFLRSITPE TQQDQIRQLK RFNVGEDCPV FDGLYSFCQT 120
121 YAGGSVGGSV KLNHGLCDIA INWAGGLHHA KKCEASGFCY VNDIVLAILE LLKQHERVLY 180
181 VDIDIHHGDG VEEAFYATDR VMTVSFHKFG DYFPGTGHIQ DIGYGSGKYY SLNVPLDDGI 240
241 DDESYHLLFK PIMGKVMEIF RPGAVVLQCG ADSLSGDRLG CFNLSIKGHA ECVKFMRSFN 300
301 VPLLLLGGGG YTIRNVARCW CYETGVALGV EVEDKMPEHE YYEYFGPDYT LHVAPSNMEN 360
361 KNSRQMLEEI RNDLLHNLSK L
|
| Detection Method: |  |
| Confidence: | 97.69897 |
| Match: | 1t64A |
| Description: | Crystal Structure of human HDAC8 complexed with Trichostatin A |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein deacetylase activity | 12.8220438463909 | bayes_pls_golite062009 |
| histone deacetylase activity | 12.6231784270509 | bayes_pls_golite062009 |
| deacetylase activity | 11.5037545953213 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | 9.39837596691907 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | 9.35288901670927 | bayes_pls_golite062009 |
| histone deacetylase activity (H3-K16 specific) | 6.99181745976945 | bayes_pls_golite062009 |
| histone deacetylase activity (H3-K9 specific) | 3.65015413158247 | bayes_pls_golite062009 |
| transcription repressor activity | 3.49362347258099 | bayes_pls_golite062009 |
| NAD-dependent protein deacetylase activity | 3.35999169984456 | bayes_pls_golite062009 |
| NAD-dependent histone deacetylase activity | 3.35999169984456 | bayes_pls_golite062009 |
| histone deacetylase activity (H3-K14 specific) | 3.25708078682827 | bayes_pls_golite062009 |
| transcription regulator activity | 3.05701986980927 | bayes_pls_golite062009 |
| histone methyltransferase activity (H3-K27 specific) | 2.60243126690148 | bayes_pls_golite062009 |
| hydrolase activity | 2.48411098726406 | bayes_pls_golite062009 |
| transcription factor binding | 2.19991964087943 | bayes_pls_golite062009 |
| NAD-independent histone deacetylase activity | 2.1026758793482 | bayes_pls_golite062009 |
| nucleic acid binding | 2.09632179671955 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.98907367314887 | bayes_pls_golite062009 |
| DNA binding | 1.982290944939 | bayes_pls_golite062009 |
| binding | 1.948738669065 | bayes_pls_golite062009 |
| protein binding | 1.77599011146146 | bayes_pls_golite062009 |
| catalytic activity | 1.68836803454021 | bayes_pls_golite062009 |
| histone methyltransferase activity (H3-K9 specific) | 1.48241147541212 | bayes_pls_golite062009 |
| specific transcriptional repressor activity | 1.37118634909958 | bayes_pls_golite062009 |
| transcription activator activity | 1.31578100431097 | bayes_pls_golite062009 |
| transcription factor activity | 1.24596588472933 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.84972377395539 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines | 0.436815987851993 | bayes_pls_golite062009 |
| histone methyltransferase activity | 0.396822865624511 | bayes_pls_golite062009 |
| transferase activity | 0.323230424038105 | bayes_pls_golite062009 |
| chromatin binding | 0.104097933861351 | bayes_pls_golite062009 |
|
Region A: Residues: [382-501] |
1 11 21 31 41 51
| | | | | |
1 QHAPSVPFQE RPPDTETPEV DEDQEDGDKR WDPDSDMDVD DDRKPIPSRV KREAVEPDTK 60
61 DKDGLKGIME RGKGCEVEVD ESGSTKVTGV NPVGVEEASV KMEEEGTNKG GAEQAFPPKT 120
121
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
