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View Structure Prediction Details

Protein: GLR28_ARATH
Organism: Arabidopsis thaliana
Length: 947 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLR28_ARATH.

Description E-value Query
Range
Subject
Range
gi|12964235 - gi|12964235|emb|CAC29254.1| ligand gated channel-like protein precursor [Arabidopsis thaliana]
630.0 [0..1] [947..1]

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Predicted Domain #1
Region A:
Residues: [1-525]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPKKNNNTF LSYFVCLFLL LEVGLGQNQI SEIKVGVVLD LNTTFSKICL TSINLALSDF  60
   61 YKDHPNYRTR LALHVRDSMK DTVQASAAAL DLIQNEQVSA IIGPIDSMQA KFMIKLANKT 120
  121 QVPTISFSAT SPLLTSIKSD YFVRGTIDDS YQVKAIAAIF ESFGWRSVVA IYVDNELGEG 180
  181 IMPYLFDALQ DVQVDRSVIP SEANDDQILK ELYKLMTRQT RVFVVHMASR LASRIFEKAT 240
  241 EIGMMEEGYV WLMTNGMTHM MRHIHHGRSL NTIDGVLGVR SHVPKSKGLE DFRLRWKRNF 300
  301 KKENPWLRDD LSIFGLWAYD STTALAMAVE KTNISSFPYN NASGSSNNMT DLGTLHVSRY 360
  361 GPSLLEALSE IRFNGLAGRF NLIDRQLESP KFEIINFVGN EERIVGFWTP SNGLVNVNSN 420
  421 KTTSFTGERF GPLIWPGKST IVPKGWEIPT NGKKIKVGVP VKKGFFNFVE VITDPITNIT 480
  481 TPKGYAIDIF EAALKKLPYS VIPQYYRFES PDDDYDDLVY KVDNG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.69897
Match: 2e4uA
Description: No description for 2e4uA was found.

Predicted Domain #2
Region A:
Residues: [526-604]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLDAVVGDVT ITAYRSLYAD FTLPYTESGV SMMVPVRDNE NKNTWVFLKP WGLDLWVTTA  60
   61 CFFVLIGFVV WLFEHRVNT

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.29
Match: 1yaeA
Description: Structure of the Kainate Receptor Subunit GluR6 Agonist Binding Domain Complexed with Domoic Acid
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [605-795]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DFRGPPHHQI GTSFWFSFST MVFAHREKVV SNLARFVVVV WCFVVLVLTQ SYTANLTSFL  60
   61 TVQRFQPAAI NVKDLIKNGD YVGYQHGAFV KDFLIKEGFN VSKLKPFGSS EECHALLSNG 120
  121 SISAAFDEVA YLRAILSQYC SKYAIVEPTF KTAGFGFAFP RNSPLTGDVS KAILNVTQGD 180
  181 EMQHIENKWF M

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.0
Match: 1gggA
Description: Glutamine-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
amine binding 4.11747486942823 bayes_pls_golite062009
transporter activity 3.92658561501282 bayes_pls_golite062009
transmembrane transporter activity 3.71430307970333 bayes_pls_golite062009
substrate-specific transporter activity 3.34421502810243 bayes_pls_golite062009
primary active transmembrane transporter activity 3.33883206510679 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 3.33572158012752 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 3.31947078781945 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 3.3164655425684 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 3.3159417475856 bayes_pls_golite062009
active transmembrane transporter activity 3.25041295044206 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.76254706952599 bayes_pls_golite062009
ATPase activity, coupled 2.65558937563899 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.36995601057551 bayes_pls_golite062009
ATPase activity 2.35388655037218 bayes_pls_golite062009
pyrophosphatase activity 2.29319753274625 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.27317031628667 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.27090852909065 bayes_pls_golite062009
peptide binding 2.13614935733644 bayes_pls_golite062009
binding 1.99193554770277 bayes_pls_golite062009
ion transmembrane transporter activity 1.84929214408108 bayes_pls_golite062009
receptor activity 1.74349172783363 bayes_pls_golite062009
molecular transducer activity 1.44487216360172 bayes_pls_golite062009
signal transducer activity 1.44487216360172 bayes_pls_golite062009
hydrolase activity 0.999095648881488 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions 0.88623763826001 bayes_pls_golite062009
transcription regulator activity 0.810341130332095 bayes_pls_golite062009
protein binding 0.782435650956845 bayes_pls_golite062009
anion transmembrane transporter activity 0.75669016367838 bayes_pls_golite062009
catalytic activity 0.674312982669564 bayes_pls_golite062009
metal ion transmembrane transporter activity 0.644907195402529 bayes_pls_golite062009
transcription factor activity 0.612192824804611 bayes_pls_golite062009
DNA binding 0.596947798194569 bayes_pls_golite062009
inorganic anion transmembrane transporter activity 0.555351218220589 bayes_pls_golite062009
amine transmembrane transporter activity 0.372828805396439 bayes_pls_golite062009
nucleic acid binding 0.367839087542125 bayes_pls_golite062009
cation transmembrane transporter activity 0.343508026849565 bayes_pls_golite062009
anion transmembrane-transporting ATPase activity 0.149393758153546 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [796-947]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQNDCPDPKT ALSSNRLSLR SFWGLFLIAG IASFLALLIF VFLFLYENRH TLCDDSEDSI  60
   61 WRKLTSLFRN FDEKDIKSHT FKSSAVHHVS SPMTQYIPSP STLQIAPRPH SPSQDRAFEL 120
  121 RRVSFTPNEE RLTTQTIHFE DEESDIECVV EQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle