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View Structure Prediction Details

Protein: PHOR_BACSU
Organism: Bacillus subtilis
Length: 579 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PHOR_BACSU.

Description E-value Query
Range
Subject
Range
gi|51974390, gi|... - gi|52140921|ref|YP_085908.1| phosphate regulon sensor protein [Bacillus cereus E33L], gi|51974390|gb...
363.0 [0..1] [577..1]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKYRVRLFS VFVVCMILVF CVLGLFLQQL FETSDQRKAE EHIEKEAKYL ASLLDAGNLN  60
   61 NQANEKIIKD AGGALDVSAS VIDTDGKVLY GSNGRS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [97-240]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADSQKVQALV SGHEGILSTT DNKLYYGLSL RSEGEKTGYV LLSASEKSDG LKGELWGMLT  60
   61 ASLCTAFIVI VYFYSSMTSR YKRSIESATN VATELSKGNY DARTYGGYIR RSDKLGHAMN 120
  121 SLAIDLMEMT RTQEMQRDRL LTVI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.48
Match: 2f95B
Description: M intermediate structure of sensory rhodopsin II/transducer complex in combination with the ground state structure
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [241-339]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENIGSGLIMI DGRGFINLVN RSYAKQFHIN PNHMLRRLYH DAFEHEEVIQ LVEDIFMTET  60
   61 KKCKLLRLPI KIERRYFEVD GVPIMGPDDE WKGIVLVFH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.09691
Match: 1y28A
Description: Crystal structure of the R220A metBJFIXL HEME domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ion transmembrane transporter activity 1.94020112661684 bayes_pls_golite062009
transcription regulator activity 1.88422125389203 bayes_pls_golite062009
binding 1.79230776794479 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.70629448457771 bayes_pls_golite062009
cation transmembrane transporter activity 1.55042643398568 bayes_pls_golite062009
DNA binding 1.54206275665781 bayes_pls_golite062009
two-component response regulator activity 1.45691562840107 bayes_pls_golite062009
nucleic acid binding 1.41817054839611 bayes_pls_golite062009
metal ion transmembrane transporter activity 1.31850321187865 bayes_pls_golite062009
transcription factor activity 1.12946889905444 bayes_pls_golite062009
protein binding 1.0133195984081 bayes_pls_golite062009
potassium channel activity 0.93265112299626 bayes_pls_golite062009
voltage-gated ion channel activity 0.92661046549451 bayes_pls_golite062009
voltage-gated cation channel activity 0.926512767264521 bayes_pls_golite062009
voltage-gated potassium channel activity 0.92204538811959 bayes_pls_golite062009
voltage-gated channel activity 0.91469735366704 bayes_pls_golite062009
ion channel activity 0.75430461252947 bayes_pls_golite062009
cation channel activity 0.73262554730695 bayes_pls_golite062009
gated channel activity 0.67217953143815 bayes_pls_golite062009
substrate-specific channel activity 0.650205954115699 bayes_pls_golite062009
passive transmembrane transporter activity 0.64202076714636 bayes_pls_golite062009
channel activity 0.64202076714636 bayes_pls_golite062009
two-component sensor activity 0.58151911764083 bayes_pls_golite062009
protein histidine kinase activity 0.56538125817883 bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor 0.518111391350209 bayes_pls_golite062009
signal transducer activity 0.441034662376355 bayes_pls_golite062009
molecular transducer activity 0.441034662376355 bayes_pls_golite062009
transporter activity 0.360938622392148 bayes_pls_golite062009
catalytic activity 0.285447488878019 bayes_pls_golite062009
transcription factor binding 0.24293756478811 bayes_pls_golite062009
transmembrane transporter activity 0.217804199010847 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [340-579]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DMTETKKLEQ MRKDFVANVS HELKTPITSI KGFTETLLDG AMEDKEALSE FLSIILKESE  60
   61 RLQSLVQDLL DLSKIEQQNF TLSIETFEPA KMLGEIETLL KHKADEKGIS LHLNVPKDPQ 120
  121 YVSGDPYRLK QVFLNLVNNA LTYTPEGGSV AINVKPREKD IQIEVADSGI GIQKEEIPRI 180
  181 FERFYRVDKD RSRNSGGTGL GLAIVKHLIE AHEGKIDVTS ELGRGTVFTV TLKRAAEKSA 240
  241 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.522879
Match: 2c2aA
Description: Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle