| Protein: | nhr-115 |
| Organism: | Caenorhabditis elegans |
| Length: | 391 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-115.
| Description | E-value | Query Range |
Subject Range |
|
|
278.0 | [0..4] | [387..108] |
|
Region A: Residues: [1-86] |
1 11 21 31 41 51
| | | | | |
1 MKKVLFPCQI CGQNSHGTHF GIVSCRACAA FFRRSVNSKW ARKGCLTNFK DKGSCFCKPC 60
61 RLRKCVEIGM DASKFQYDRD AISAIK
|
| Detection Method: |  |
| Confidence: | 16.69897 |
| Match: | 2hanB |
| Description: | No description for 2hanB was found. |
| Term | Confidence | Notes |
| transcription regulator activity | 4.00967542385368 | bayes_pls_golite062009 |
| DNA binding | 3.60745514727532 | bayes_pls_golite062009 |
| nucleic acid binding | 3.47256374293954 | bayes_pls_golite062009 |
| receptor activity | 3.23961300660788 | bayes_pls_golite062009 |
| binding | 2.96409924710655 | bayes_pls_golite062009 |
| transcription activator activity | 2.9532663930699 | bayes_pls_golite062009 |
| transcription factor activity | 2.90769972671972 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.72967350701574 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 2.55186574506963 | bayes_pls_golite062009 |
| protein binding | 2.44501340584871 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.40923942043513 | bayes_pls_golite062009 |
| molecular transducer activity | 2.3211572231948 | bayes_pls_golite062009 |
| signal transducer activity | 2.3211572231948 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 1.91348392022358 | bayes_pls_golite062009 |
| transcription repressor activity | 1.88834375049208 | bayes_pls_golite062009 |
| hormone receptor binding | 1.8288193687002 | bayes_pls_golite062009 |
| steroid hormone receptor binding | 1.72196998170947 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 1.49515149729803 | bayes_pls_golite062009 |
| androgen receptor binding | 1.48596869620742 | bayes_pls_golite062009 |
| transcription factor binding | 1.38523780690867 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 1.28090460550476 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.26452462867497 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.61572149323953 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.58115018700114 | bayes_pls_golite062009 |
| structural constituent of ribosome | 0.525229083081488 | bayes_pls_golite062009 |
| structural molecule activity | 0.281585397269403 | bayes_pls_golite062009 |
| catalytic activity | 0.101795606736461 | bayes_pls_golite062009 |
|
Region A: Residues: [87-391] |
1 11 21 31 41 51
| | | | | |
1 HPKIFPSVSY YVGRPEFLMF SDSNVTSQKT FIDVQNLVFE VSRYLDHGCE TPIYAENQLK 60
61 KLTLGFKLMQ FDYQNVKFFD KIGKAEFIDI IEYYFLTVAK WIAHFDEFRK LDQSLQIKLL 120
121 QAIWHVWSKI HKCASTAFYR KSNPNAKPTQ KILRNVCMDR MHVHKLDTSW MSDYPTEHVT 180
181 RFMLTHHVYD FKIVESLLKL DPTDVELTFM FAQLCFEYAG KRFQGEILKI TDHFQQVLSN 240
241 DLHHYYITDQ RRERYFQRLT DLMKVNNLIQ RSIWETRPHR ELGRVFEISK LEFSHPEMFD 300
301 DSGFC
|
| Detection Method: | |
| Confidence: | 34.0 |
| Match: | 1xdkB |
| Description: | Crystal Structure of the RARbeta/RXRalpha Ligand Binding Domain Heterodimer in Complex with 9-cis Retinoic Acid and a Fragment of the TRAP220 Coactivator |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| receptor activity | 5.63850766931612 | bayes_pls_golite062009 |
| transcription regulator activity | 5.53061626347066 | bayes_pls_golite062009 |
| DNA binding | 4.92165988569962 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 4.81441024181511 | bayes_pls_golite062009 |
| nucleic acid binding | 4.78024150262074 | bayes_pls_golite062009 |
| molecular transducer activity | 4.63434910389609 | bayes_pls_golite062009 |
| signal transducer activity | 4.63434910389609 | bayes_pls_golite062009 |
| transcription activator activity | 4.53302455129434 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 4.11614358606713 | bayes_pls_golite062009 |
| transcription factor activity | 4.0914094580319 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 3.91470119037087 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 3.89763470197726 | bayes_pls_golite062009 |
| binding | 3.85318710398432 | bayes_pls_golite062009 |
| transcription repressor activity | 3.83878598697109 | bayes_pls_golite062009 |
| hormone receptor binding | 3.79647267365529 | bayes_pls_golite062009 |
| protein binding | 3.21524787168952 | bayes_pls_golite062009 |
| transcription activator binding | 2.98235973123409 | bayes_pls_golite062009 |
| transcription factor binding | 2.68044489404568 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.38308182853979 | bayes_pls_golite062009 |
| transcription coactivator activity | 2.27959329058894 | bayes_pls_golite062009 |
| transmembrane receptor activity | 1.79803787243894 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.73827483890179 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 1.59968001933699 | bayes_pls_golite062009 |
| estrogen response element binding | 1.56094639526803 | bayes_pls_golite062009 |
| estrogen receptor activity | 1.47290778095383 | bayes_pls_golite062009 |
| retinoid X receptor binding | 1.45560845709347 | bayes_pls_golite062009 |
| ecdysteroid hormone receptor activity | 1.35110271601538 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.34794228300778 | bayes_pls_golite062009 |
| promoter binding | 1.28787959668198 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 1.06874057850256 | bayes_pls_golite062009 |
| receptor binding | 1.04943671621651 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.995333369475571 | bayes_pls_golite062009 |
| retinoic acid receptor activity | 0.853869057774515 | bayes_pls_golite062009 |
| protein dimerization activity | 0.797229273848179 | bayes_pls_golite062009 |
| steroid hormone receptor binding | 0.754240851368212 | bayes_pls_golite062009 |
| lipid binding | 0.74826259948949 | bayes_pls_golite062009 |
| hormone binding | 0.70374209842132 | bayes_pls_golite062009 |
| retinoic acid binding | 0.676688935879073 | bayes_pls_golite062009 |
| protein N-terminus binding | 0.57701453824007 | bayes_pls_golite062009 |
| thyroid hormone receptor activity | 0.49784404390361 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.47826452126899 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.45265806678057 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.42652610679613 | bayes_pls_golite062009 |
| ligand-regulated transcription factor activity | 0.202197503742221 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.15737167800277 | bayes_pls_golite062009 |
| catalytic activity | 0.106902059021677 | bayes_pls_golite062009 |
