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View Structure Prediction Details

Protein: pqe-1
Organism: Caenorhabditis elegans
Length: 573 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pqe-1.

Description E-value Query
Range		 Subject
Range
pqe-1 - status:Confirmed UniProt:Q10124 protein_id:AAM45369.1
 377.0 [0..16] [573..1]

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Predicted Domain #1
Region A:
Residues: [1-88] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNVSSPSTQA SHFNQFQKRP TSSASVDSND DGVHIPAKRM AHASSVPGPS RSKPPMIGAV  60
   61 KNRPNHTEML DKRNKESEEK RRKDRDEL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.05
Match: 2grxC
Description: No description for 2grxC was found.

Predicted Domain #2
Region A:
Residues: [89-304] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ERLRNKKHTT EEEKIKMARL QNALKVVGKA AGLKATVKKE LTGSPAKKQK PAPAVPKILD  60
   61 FSVGRTFTAI RQTAIKLVFD TFLERDSPNA AREAQEFELS IAKQYTDGQK YRINIGHKVA 120
  121 ALRKENTSGI LEVNKNAVSH DKILAGGPKD NCTVARGRKT HVDHRQLSIE KLHPLLLQFK 180
  181 LTTSELETNA YPMRRDGSTK AVSIADTVYT QNKKMF

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.02
Match: 1pqvS
Description: RNA polymerase II-TFIIS complex
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [305-396] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDDYDMSRNC SRCNKEFKLS PNGTMIRSTG ICRYHNRGVA INGKRDTFRK RYSCCNEEFN  60
   61 VALGCKFSDV HVTDQLFKKE LSTFVSTPVP VP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.974
Match: 1zu1A
Description: Solution Structure of the N-terminal Zinc Fingers of the Xenopus laevis double stranded RNA binding protein ZFa
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.37529385176635 bayes_pls_golite062009
DNA binding 3.3049326844117 bayes_pls_golite062009
nucleic acid binding 3.24981360535232 bayes_pls_golite062009
transcription factor activity 2.44389510173662 bayes_pls_golite062009
binding 2.40458515823407 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.57041104288348 bayes_pls_golite062009
transcription activator activity 1.20323819132961 bayes_pls_golite062009
RNA binding 0.84315767580466 bayes_pls_golite062009
sequence-specific DNA binding 0.732558534458316 bayes_pls_golite062009
protein binding 0.721263040163177 bayes_pls_golite062009
transcription repressor activity 0.686318575498149 bayes_pls_golite062009
chromatin binding 0.626365497850853 bayes_pls_golite062009
transcription factor binding 0.515821187939278 bayes_pls_golite062009
catalytic activity 0.263007611601737 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.200483461579207 bayes_pls_golite062009
transcription cofactor activity 0.113925660147477 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [397-573] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDQRSTRVYA LDCEMVYTIA GPALARLTMV DMQRNRVLDV FVKPPTDVLD PNTEFSGLTM  60
   61 EQINSAPDTL KTCHQKLFKY VNADTILIGH SLESDLKAMR VVHKNVIDTA ILFRSTRDTK 120
  121 VALKVLSAKL LHKNIQGDNE DAIGHDSMED ALTCVDLIFY GLRNPESIAI REANTNC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.0
Match: 1wljA
Description: human ISG20
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nuclease activity 2.65398446409354 bayes_pls_golite062009
ribonuclease activity 2.17677493546761 bayes_pls_golite062009
endoribonuclease activity, producing 5'-phosphomonoesters 1.74431545836806 bayes_pls_golite062009
exoribonuclease activity 1.70600098208524 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 1.65911933935463 bayes_pls_golite062009
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1.59628511603826 bayes_pls_golite062009
hydrolase activity 1.52504970608306 bayes_pls_golite062009
exonuclease activity 1.4327316829508 bayes_pls_golite062009
3'-5'-exoribonuclease activity 1.42069917818896 bayes_pls_golite062009
catalytic activity 1.25233849524628 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.19753926150484 bayes_pls_golite062009
1.18236432793831 bayes_pls_golite062009
transcription regulator activity 1.10433412699603 bayes_pls_golite062009
nucleic acid binding 1.04079362397031 bayes_pls_golite062009
endonuclease activity 0.991569665925888 bayes_pls_golite062009
3'-5' exonuclease activity 0.86862629020506 bayes_pls_golite062009
DNA binding 0.860359347662869 bayes_pls_golite062009
binding 0.762139256580538 bayes_pls_golite062009
RNA binding 0.750194803368593 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.389326716045122 bayes_pls_golite062009
transcription factor activity 0.332903382446869 bayes_pls_golite062009
ribonuclease H activity 0.244270343650265 bayes_pls_golite062009
endoribonuclease activity 0.016619833072142 bayes_pls_golite062009
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