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Protein Overview: pqe-1

General Information:
Name(s) found: pqe-1 / CE30673 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00004095 locus:pqe-1 Putative RNA exonuclease pqe-1 status:Confirmed UniProt:Q10124 protein_id:CCD71613.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 558 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEALink to PubMed article]
    Biological Process: NONE FOUND
    Molecular Function: exonuclease activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKRPTSSAS VDSNDDGVHI PAKRMAHASS VPGPSRSKPP MIGAVKNRPN HTEMLDKRNK  60
   61 ESEEKRRKDR DELERLRNKK HTTEEEKIKM ARLQNALKVV GKAAGLKATV KKELTGSPAK 120
  121 KQKPAPAVPK ILDFSVGRTF TAIRQTAIKL VFDTFLERDS PNAAREAQEF ELSIAKQYTD 180
  181 GQKYRINIGH KVAALRKENT SGILEVNKNA VSHDKILAGG PKDNCTVARG RKTHVDHRQL 240
  241 SIEKLHPLLL QFKLTTSELE TNAYPMRRDG STKAVSIADT VYTQNKKMFL DDYDMSRNCS 300
  301 RCNKEFKLSP NGTMIRSTGI CRYHNRGVAI NGKRDTFRKR YSCCNEEFNV ALGCKFSDVH 360
  361 VTDQLFKKEL STFVSTPVPV PNDQRSTRVY ALDCEMVYTI AGPALARLTM VDMQRNRVLD 420
  421 VFVKPPTDVL DPNTEFSGLT MEQINSAPDT LKTCHQKLFK YVNADTILIG HSLESDLKAM 480
  481 RVVHKNVIDT AILFRSTRDT KVALKVLSAK LLHKNIQGDN EDAIGHDSME DALTCVDLIF 540
  541 YGLRNPESIA IREANTNC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..76] FFAS03 1.03 No description for 2grxC was found.
    2 View Details [77..348] FFAS03 0.96 RNA polymerase II-TFIIS complex
    3 View Details [349..558] PSI-BLAST 37.69897 No description for 2guiA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • nuclease activity
    		•  2.65398446409354 bayes_pls_golite062009
  • ribonuclease activity
    		•  2.17677493546761 bayes_pls_golite062009
  • endoribonuclease activity, producing 5'-phosphomonoesters
    		•  1.74431545836806 bayes_pls_golite062009
  • exoribonuclease activity
    		•  1.70600098208524 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  1.65911933935463 bayes_pls_golite062009
  • endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  1.59628511603826 bayes_pls_golite062009
  • hydrolase activity
    		•  1.52504970608306 bayes_pls_golite062009
  • exonuclease activity
    		•  1.4327316829508 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  1.42069917818896 bayes_pls_golite062009
  • catalytic activity
    		•  1.25233849524628 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  1.19753926150484 bayes_pls_golite062009
    		• 1.18236432793831 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.10433412699603 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.04079362397031 bayes_pls_golite062009
  • endonuclease activity
    		•  0.991569665925888 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  0.86862629020506 bayes_pls_golite062009
  • DNA binding
    		•  0.860359347662869 bayes_pls_golite062009
  • binding
    		•  0.762139256580538 bayes_pls_golite062009
  • RNA binding
    		•  0.750194803368593 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.389326716045122 bayes_pls_golite062009
  • transcription factor activity
    		•  0.332903382446869 bayes_pls_golite062009
  • ribonuclease H activity
    		•  0.244270343650265 bayes_pls_golite062009
  • endoribonuclease activity
    		•  0.016619833072142 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle