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Protein Overview: pqe-1

General Information:
Name(s) found: pqe-1 / CE30674 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00004095 locus:pqe-1 Putative RNA exonuclease pqe-1 status:Confirmed UniProt:Q10124 protein_id:CCD71614.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 573 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEALink to PubMed article]
    Biological Process: NONE FOUND
    Molecular Function: exonuclease activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNVSSPSTQA SHFNQFQKRP TSSASVDSND DGVHIPAKRM AHASSVPGPS RSKPPMIGAV  60
   61 KNRPNHTEML DKRNKESEEK RRKDRDELER LRNKKHTTEE EKIKMARLQN ALKVVGKAAG 120
  121 LKATVKKELT GSPAKKQKPA PAVPKILDFS VGRTFTAIRQ TAIKLVFDTF LERDSPNAAR 180
  181 EAQEFELSIA KQYTDGQKYR INIGHKVAAL RKENTSGILE VNKNAVSHDK ILAGGPKDNC 240
  241 TVARGRKTHV DHRQLSIEKL HPLLLQFKLT TSELETNAYP MRRDGSTKAV SIADTVYTQN 300
  301 KKMFLDDYDM SRNCSRCNKE FKLSPNGTMI RSTGICRYHN RGVAINGKRD TFRKRYSCCN 360
  361 EEFNVALGCK FSDVHVTDQL FKKELSTFVS TPVPVPNDQR STRVYALDCE MVYTIAGPAL 420
  421 ARLTMVDMQR NRVLDVFVKP PTDVLDPNTE FSGLTMEQIN SAPDTLKTCH QKLFKYVNAD 480
  481 TILIGHSLES DLKAMRVVHK NVIDTAILFR STRDTKVALK VLSAKLLHKN IQGDNEDAIG 540
  541 HDSMEDALTC VDLIFYGLRN PESIAIREAN TNC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..88] FFAS03 1.05 No description for 2grxC was found.
    2 View Details [89..304] FFAS03 1.02 RNA polymerase II-TFIIS complex
    3 View Details [305..396] FFAS03 0.974 Solution Structure of the N-terminal Zinc Fingers of the Xenopus laevis double stranded RNA binding protein ZFa
    4 View Details [397..573] PSI-BLAST 38.0 human ISG20

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • transcription regulator activity
    		•  3.37529385176635 bayes_pls_golite062009
  • DNA binding
    		•  3.3049326844117 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.24981360535232 bayes_pls_golite062009
  • transcription factor activity
    		•  2.44389510173662 bayes_pls_golite062009
  • binding
    		•  2.40458515823407 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.57041104288348 bayes_pls_golite062009
  • transcription activator activity
    		•  1.20323819132961 bayes_pls_golite062009
  • RNA binding
    		•  0.84315767580466 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.732558534458316 bayes_pls_golite062009
  • protein binding
    		•  0.721263040163177 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.686318575498149 bayes_pls_golite062009
  • chromatin binding
    		•  0.626365497850853 bayes_pls_golite062009
  • transcription factor binding
    		•  0.515821187939278 bayes_pls_golite062009
  • catalytic activity
    		•  0.263007611601737 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.200483461579207 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.113925660147477 bayes_pls_golite062009
    4
    Term Confidence Notes
  • nuclease activity
    		•  2.65398446409354 bayes_pls_golite062009
  • ribonuclease activity
    		•  2.17677493546761 bayes_pls_golite062009
  • endoribonuclease activity, producing 5'-phosphomonoesters
    		•  1.74431545836806 bayes_pls_golite062009
  • exoribonuclease activity
    		•  1.70600098208524 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  1.65911933935463 bayes_pls_golite062009
  • endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  1.59628511603826 bayes_pls_golite062009
  • hydrolase activity
    		•  1.52504970608306 bayes_pls_golite062009
  • exonuclease activity
    		•  1.4327316829508 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  1.42069917818896 bayes_pls_golite062009
  • catalytic activity
    		•  1.25233849524628 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  1.19753926150484 bayes_pls_golite062009
    		• 1.18236432793831 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.10433412699603 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.04079362397031 bayes_pls_golite062009
  • endonuclease activity
    		•  0.991569665925888 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  0.86862629020506 bayes_pls_golite062009
  • DNA binding
    		•  0.860359347662869 bayes_pls_golite062009
  • binding
    		•  0.762139256580538 bayes_pls_golite062009
  • RNA binding
    		•  0.750194803368593 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.389326716045122 bayes_pls_golite062009
  • transcription factor activity
    		•  0.332903382446869 bayes_pls_golite062009
  • ribonuclease H activity
    		•  0.244270343650265 bayes_pls_golite062009
  • endoribonuclease activity
    		•  0.016619833072142 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle