| Protein: | cng-1 |
| Organism: | Caenorhabditis elegans |
| Length: | 695 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cng-1.
| Description | E-value | Query Range |
Subject Range |
|
|
377.0 | [0..3] | [679..370] |
|
Region A: Residues: [1-103] |
1 11 21 31 41 51
| | | | | |
1 MLKGMLDTVK LRIFLFLTSF ELLETGSTFL TQQWRNCDQN LFNEYLKTYK NGGYSQFEAL 60
61 RGWMQRAQKR LHLFRKNDVD IETNFREALR EEQEDDEKSS GFM
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [104-394] |
1 11 21 31 41 51
| | | | | |
1 SFTVDEHSNT FYLWTGLVSL VALHPLVFTA LSVFQDVHPF LRNTGPLNLL LDLVNILDLI 60
61 AHTRIEYVEN GVAVKNLSKL MHHRLKSTFF ILDVIAVVPA ESLHIFGDSF FWSRINRLTK 120
121 CYRLFDFSTQ TDTRTTSPHA FGLFKLIFIC VVIFHWNGCL YFYISKVYNY TTARLEHWIF 180
181 SYDKIINPIL ATCVTDIPNH RDFCDTDDLL ITHLPENEVQ FTVTDYMTTW ENKTTTIKFA 240
241 NFFRQYALSF YWSALTLVTL GEQPSPCTTF QNAFEIGDTL LGLVIFAVIV G
|
| Detection Method: | |
| Confidence: | 4.96 |
| Match: | 2a0lA |
| Description: | Crystal structure of KvAP-33H1 Fv complex |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| cation channel activity | 8.8271544979352 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 8.821528894161 | bayes_pls_golite062009 |
| voltage-gated cation channel activity | 8.74133052120115 | bayes_pls_golite062009 |
| ion channel activity | 8.5319589047463 | bayes_pls_golite062009 |
| gated channel activity | 8.44554798975713 | bayes_pls_golite062009 |
| voltage-gated ion channel activity | 8.43463411234305 | bayes_pls_golite062009 |
| voltage-gated channel activity | 8.4117395754193 | bayes_pls_golite062009 |
| voltage-gated potassium channel activity | 8.36000486601638 | bayes_pls_golite062009 |
| channel activity | 8.32023913192244 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 8.32023913192244 | bayes_pls_golite062009 |
| substrate-specific channel activity | 8.30986502722514 | bayes_pls_golite062009 |
| potassium channel activity | 8.23401095904851 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 5.43467612453479 | bayes_pls_golite062009 |
| ligand-gated channel activity | 5.43467612453479 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 4.88789838906314 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 4.80939024913503 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 4.43208330555032 | bayes_pls_golite062009 |
| transporter activity | 2.77619896060397 | bayes_pls_golite062009 |
| inward rectifier potassium channel activity | 2.77094691956851 | bayes_pls_golite062009 |
| transmembrane transporter activity | 2.65613366364107 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 2.60593795082679 | bayes_pls_golite062009 |
|
Region A: Residues: [395-616] |
1 11 21 31 41 51
| | | | | |
1 DVGNMVVAIN LRKSEFENVL DGCKRFMVYR KVPNLLRKKA VEYFAYVWAH GGAQVDEEEI 60
61 AEFLPPRLFG EIAVEIHMDT LKKVKLFESC DPRLLYELIL KLQLRVYSPM DYICKKGDVG 120
121 TEMYIVKEGF VEVVSEDGQT IFVTLPAGFV FGELSILNIP GNKNKNLRTA SVRSKGYSDL 180
181 YVLDKEDLWE ALHEYPQAKD SLIQKGIQIL EKDKMIDPNM VD
|
| Detection Method: | |
| Confidence: | 29.30103 |
| Match: | 1q3eA |
| Description: | HCN2J 443-645 in the presence of cGMP |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| cyclic nucleotide-gated ion channel activity | 10.1422916734545 | bayes_pls_golite062009 |
| intracellular cyclic nucleotide activated cation channel activity | 10.1422916734545 | bayes_pls_golite062009 |
| intracellular ligand-gated ion channel activity | 9.72053268940283 | bayes_pls_golite062009 |
| cation channel activity | 9.48749374439976 | bayes_pls_golite062009 |
| ion channel activity | 9.4846197809463 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 9.3929063879608 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 9.25176207085973 | bayes_pls_golite062009 |
| channel activity | 9.25176207085973 | bayes_pls_golite062009 |
| substrate-specific channel activity | 9.2472549851376 | bayes_pls_golite062009 |
| intracellular cGMP activated cation channel activity | 9.19973076787954 | bayes_pls_golite062009 |
| gated channel activity | 9.19042473454294 | bayes_pls_golite062009 |
| cGMP binding | 7.7575871125398 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 7.41584542512987 | bayes_pls_golite062009 |
| ligand-gated channel activity | 7.41584542512987 | bayes_pls_golite062009 |
| cyclic nucleotide binding | 7.37322432929433 | bayes_pls_golite062009 |
| voltage-gated ion channel activity | 6.57272328088253 | bayes_pls_golite062009 |
| voltage-gated channel activity | 6.54930851487319 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 5.54400173845933 | bayes_pls_golite062009 |
| GMP binding | 5.49455172024846 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 5.34760703274696 | bayes_pls_golite062009 |
| potassium channel activity | 5.29889968906368 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 5.1138025954757 | bayes_pls_golite062009 |
| voltage-gated cation channel activity | 4.96516802098805 | bayes_pls_golite062009 |
| voltage-gated potassium channel activity | 4.52895684111035 | bayes_pls_golite062009 |
| intracellular cAMP activated cation channel activity | 3.95109938608832 | bayes_pls_golite062009 |
| transporter activity | 3.30740141256752 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 3.24402760485462 | bayes_pls_golite062009 |
| transmembrane transporter activity | 3.22443361822344 | bayes_pls_golite062009 |
| molecular transducer activity | 1.7487659479534 | bayes_pls_golite062009 |
| signal transducer activity | 1.7487659479534 | bayes_pls_golite062009 |
| binding | 1.59096092728475 | bayes_pls_golite062009 |
| enzyme regulator activity | 1.40720858109605 | bayes_pls_golite062009 |
| GTPase regulator activity | 0.930640481652164 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 0.910527807644534 | bayes_pls_golite062009 |
| guanyl-nucleotide exchange factor activity | 0.848189810874263 | bayes_pls_golite062009 |
| protein binding | 0.81302068072988 | bayes_pls_golite062009 |
|
Region A: Residues: [617-695] |
1 11 21 31 41 51
| | | | | |
1 DEDESFNGPI EDYMEHLEHE ILKITKMIDQ AEDKIHKSNQ KMKTRLFGME MDLVHEIKEL 60
61 LKENSWKRIA RFADGVTVL
|
| Detection Method: | |
| Confidence: | 13.522879 |
| Match: | 2gauA |
| Description: | No description for 2gauA was found. |
| Term | Confidence | Notes |
| binding | 2.88885372623841 | bayes_pls_golite062009 |
| transcription regulator activity | 2.7317847461735 | bayes_pls_golite062009 |
| DNA binding | 2.48559849769138 | bayes_pls_golite062009 |
| nucleic acid binding | 2.38705965090247 | bayes_pls_golite062009 |
| transcription factor activity | 1.86553483886232 | bayes_pls_golite062009 |
| signal transducer activity | 1.42015496657117 | bayes_pls_golite062009 |
| molecular transducer activity | 1.42015496657117 | bayes_pls_golite062009 |
| protein binding | 0.753698599635855 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.57001406505152 | bayes_pls_golite062009 |
| transcription activator activity | 0.376344018138683 | bayes_pls_golite062009 |
| transcription repressor activity | 0.296777088118869 | bayes_pls_golite062009 |
