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View Structure Prediction Details

Protein: dpy-31
Organism: Caenorhabditis elegans
Length: 592 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dpy-31.

Description E-value Query
Range
Subject
Range
gi|7506745 - gi|7506745|pir||T16761 hypothetical protein R151.5 - Caenorhabditis elegans
375.0 [0..1] [592..1]

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Predicted Domain #1
Region A:
Residues: [1-87]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHKIFIIFGL LSLCAAHSLR DLSNKDEEDP PSSAPGVRKR RMMSEEDQKT VDYYMDKLNK  60
   61 LADEKHPEEI ERHKNPELVA WDRKRDS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [88-298]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VLNPEEQGKF FQGDIVLYPE QAKALYEQAL TEGKTRVKRK FIGSNLRRWD ASRPIIYAFD  60
   61 GSHTQREQRI IELALEHWHN ITCLNFQRND QANSGNRIVF TDVDGCASNV GRHPLGEEQL 120
  121 VSLAPECIRL GVIAHEVAHA LGFWHEQSRP DRDQYVTVRW ENIDKDSKGQ FLKEDPDDVD 180
  181 NAGVPYDYGS IMHYRSKAFS KFDDLYTIST Y

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.221849
Match: 1astA
Description: STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 4.1917763812737 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 3.85190688399485 bayes_pls_golite062009
metallopeptidase activity 3.22757426039234 bayes_pls_golite062009
endopeptidase activity 2.98133341931091 bayes_pls_golite062009
hydrolase activity 2.78513171530601 bayes_pls_golite062009
metalloendopeptidase activity 2.54952091441017 bayes_pls_golite062009
binding 0.910292205820092 bayes_pls_golite062009
catalytic activity 0.891187593353827 bayes_pls_golite062009
integrin binding 0.65764952681937 bayes_pls_golite062009
protein binding 0.553658909577001 bayes_pls_golite062009
exopeptidase activity 0.492456025063956 bayes_pls_golite062009
receptor activity 0.332822250208465 bayes_pls_golite062009
transmembrane receptor activity 0.136560284009247 bayes_pls_golite062009
aminopeptidase activity 0.00533877867882504 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [299-592]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTDYQKTIGQ RDQLSFNDIR LMNKIYCSAV CPSKLPCQRG GYTDPRRCDR CRCPDGFTGQ  60
   61 YCEQVMPGYG ATCGGKISLT RSTTRISSPG YPREFKEGQE CSWLLVAPPG HIVEFQFIGE 120
  121 FEMYCKIRHS LCMDYVEVRN STDFANTGMR YCCYGTPPTR IRSATTDMVV LFRSFYRGGK 180
  181 GFEARARAVP EAGNWNSWSP WTACSATCGA CGSRMRTRTC PPGNACSGEP VETQICNTQA 240
  241 CTGMCAQKRE EEGQCGGFLS LLRGVRCRQE KTVMAPCENA CCPGFTLQRG RCVR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.522879
Match: 1n7dA
Description: Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle