| Protein: | hch-1 |
| Organism: | Caenorhabditis elegans |
| Length: | 605 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hch-1.
| Description | E-value | Query Range |
Subject Range |
|
|
347.0 | [0..17] | [585..56] |
|
Region A: Residues: [1-71] |
1 11 21 31 41 51
| | | | | |
1 MVSYWPVLIV LCLLPICHAK SYFADFVNGK GPFKQADALK FMDKMTILNK LQADILGIPQ 60
61 PDEFSALDFE D
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [72-263] |
1 11 21 31 41 51
| | | | | |
1 KIESKPDEIP YLFEGDMVLT DEQMDLIIKN VRDQYWARKS STNEFLYAIR GKRSMTSFLS 60
61 ERWSFPVPYY IDTSSGVNTN AVLAGVAKWE QETCARFTRL NSYSSSSRQN ALRFISGNGC 120
121 YSNIGKVSRF PQDVSIGWGC TSLGTVCHEI GHALGFYHEQ ARYDRDDYVS ILTQNIQDMY 180
181 LSQFTKQSAS SM
|
| Detection Method: | |
| Confidence: | 40.0 |
| Match: | 1astA |
| Description: | STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| peptidase activity | 4.1917763812737 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 3.85190688399485 | bayes_pls_golite062009 |
| metallopeptidase activity | 3.22757426039234 | bayes_pls_golite062009 |
| endopeptidase activity | 2.98133341931091 | bayes_pls_golite062009 |
| hydrolase activity | 2.78513171530601 | bayes_pls_golite062009 |
| metalloendopeptidase activity | 2.54952091441017 | bayes_pls_golite062009 |
| transporter activity | 1.28982382930122 | bayes_pls_golite062009 |
| binding | 1.19918194301835 | bayes_pls_golite062009 |
| integrin binding | 1.14306661858478 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.0688261398267 | bayes_pls_golite062009 |
| catalytic activity | 0.891187593353827 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.798767221679673 | bayes_pls_golite062009 |
| protein binding | 0.553658909577001 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.543737159152136 | bayes_pls_golite062009 |
| exopeptidase activity | 0.492456025063956 | bayes_pls_golite062009 |
| receptor activity | 0.332822250208465 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.241890854867053 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.136560284009247 | bayes_pls_golite062009 |
| aminopeptidase activity | 0.00533877867882504 | bayes_pls_golite062009 |
|
Region A: Residues: [264-605] |
1 11 21 31 41 51
| | | | | |
1 VDYGVGYDYG SVMHYDQAAF SSTGGNTIAT RDPNFQATIG QRVAPSFADV KRINFAYCNS 60
61 TCSNYLDCQN GGYINPNDCN NCKCPPGFGG QLCDVAGTNS NGCGAGDITA TSSIQTISAS 120
121 GALTCNYVIK APVGAKVYFQ MTAATFSRYS PCTTNYLEIN YGRDFSRVGA RFCASYPTIS 180
181 LSETNTLVVI YKGVNGARFS LNYRYDPVTF STSAPTTTST TTTTAPITVP TVSPTTTTTR 240
241 QTTTTARTST TTTTTQAPPT TTTSTSQCAS WSACSAQCGG CGTQSRRCGT YVETVYCNTN 300
301 PCTGGYCCRP FFYVTSFGTG YCRRPGADTP AAPQRYVEQR KG
|
| Detection Method: | |
| Confidence: | 5.69897 |
| Match: | 1n7dA |
| Description: | Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| ErbB-2 class receptor binding | 2.43291483229075 | bayes_pls_golite062009 |
| ErbB-3 class receptor binding | 2.40375706430672 | bayes_pls_golite062009 |
| receptor binding | 2.19335005546698 | bayes_pls_golite062009 |
| binding | 2.19152785302602 | bayes_pls_golite062009 |
| protein binding | 1.99839937208979 | bayes_pls_golite062009 |
| transcription factor binding | 0.89765738417424 | bayes_pls_golite062009 |
| epidermal growth factor receptor binding | 0.82506902766668 | bayes_pls_golite062009 |
| growth factor activity | 0.473340802107115 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.225989825753998 | bayes_pls_golite062009 |
| pattern binding | 0.0196006376432096 | bayes_pls_golite062009 |
