YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: dkf-1
Organism: Caenorhabditis elegans
Length: 722 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dkf-1.

Description E-value Query
Range
Subject
Range
gi|54303904 - gi|54303904|gb|AAV33302.1| aging-associated gene 6 protein [Homo sapiens]
486.0 [0..63] [720..1]

Back

Predicted Domain #1
Region A:
Residues: [1-80]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDGSQGSTDY GDHVVLRYGG TREMVPLIRH EQMLDMLMER ARQIVQGFGN LDTRNMYLFR  60
   61 HEYNSPTLLY PITSASQITS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.522879
Match: 1rrbA
Description: THE RAS-BINDING DOMAIN OF RAF-1 FROM RAT, NMR, 1 STRUCTURE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.35732272412639 bayes_pls_golite062009
tubulin binding 2.17448062213288 bayes_pls_golite062009
cytoskeletal protein binding 2.10724980780815 bayes_pls_golite062009
microtubule binding 1.93078273560396 bayes_pls_golite062009
protein binding 1.86841453215444 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.63853240069891 bayes_pls_golite062009
kinase activity 1.62384132584197 bayes_pls_golite062009
protein kinase activity 1.5956463895254 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.51475136357956 bayes_pls_golite062009
molecular transducer activity 1.50825759862682 bayes_pls_golite062009
signal transducer activity 1.50825759862682 bayes_pls_golite062009
transferase activity 1.25776281736571 bayes_pls_golite062009
protein serine/threonine kinase activity 0.673589832597734 bayes_pls_golite062009
structural constituent of ribosome 0.599634454232833 bayes_pls_golite062009
structural molecule activity 0.576819726104993 bayes_pls_golite062009
structure-specific DNA binding 0.562594294957137 bayes_pls_golite062009
transcription regulator activity 0.546422207034767 bayes_pls_golite062009
nucleic acid binding 0.525788464472489 bayes_pls_golite062009
DNA binding 0.422142077605877 bayes_pls_golite062009
GTPase regulator activity 0.334601927012824 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 0.315664702789604 bayes_pls_golite062009
receptor binding 0.298046142314417 bayes_pls_golite062009
enzyme binding 0.240262781026149 bayes_pls_golite062009
enzyme regulator activity 0.162163146322721 bayes_pls_golite062009
protein tag 0.00311613478935058 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [81-241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSILEIILVD RTEAAVIPHV VEPESYMRPT FCDFCGEMLT GLMRQGVKCK NCNGNFHKRC  60
   61 SNAARNNCGA PGAPGAQPSR PPILPPIPTT PTGFPVAALS TPTGLPHTLI EHSYRQFTVC 120
  121 KVCDHLLVGL VKQGLKCRDC GVNVHRKCAM ELASNCVLSE N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.522879
Match: 1xa6A
Description: Crystal Structure of the Human Beta2-Chimaerin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
diacylglycerol kinase activity 2.62274004397594 bayes_pls_golite062009
binding 2.36195429973813 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 2.12546774457691 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 2.10625597744594 bayes_pls_golite062009
kinase activity 2.03632850156074 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.8531437045627 bayes_pls_golite062009
protein kinase activity 1.80739081420522 bayes_pls_golite062009
molecular transducer activity 1.70650638346167 bayes_pls_golite062009
signal transducer activity 1.70650638346167 bayes_pls_golite062009
transferase activity 1.4550521488922 bayes_pls_golite062009
GTPase regulator activity 1.39167263636091 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 1.37139209958305 bayes_pls_golite062009
protein binding 1.29100556128076 bayes_pls_golite062009
transcription regulator activity 1.19392095748004 bayes_pls_golite062009
protein serine/threonine kinase activity 0.956859696337723 bayes_pls_golite062009
enzyme regulator activity 0.911061212692491 bayes_pls_golite062009
guanyl-nucleotide exchange factor activity 0.907368864863833 bayes_pls_golite062009
nucleic acid binding 0.746688776397071 bayes_pls_golite062009
small GTPase regulator activity 0.661240850692236 bayes_pls_golite062009
DNA binding 0.618071969351071 bayes_pls_golite062009
kinase binding 0.494958567742569 bayes_pls_golite062009
catalytic activity 0.194464246602439 bayes_pls_golite062009
transcription factor activity 0.0701429188109299 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [242-411]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AISRVNFTDP EGPGSSSSDN IPLFRLPGQV GTRATEKKKL EGWMMHFILS DPERRLKHYW  60
   61 MMQSNAIHLY NEYSEGIGVN PNRVYRIIPL AEITSVVQNN GKSVLAKHPP HCFEIRTTTN 120
  121 TVFCVGEDYH AFSGGPPKKI PRSMSVRPSS NTTMWFQFIK ESLQPPSRNE 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.04
Match: 2coaA
Description: Solution structure of the PH domain of protein kinase C, D2 type from human
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.73312450062269 bayes_pls_golite062009
cytoskeletal protein binding 2.35640415776708 bayes_pls_golite062009
actin binding 2.15139219039706 bayes_pls_golite062009
signal transducer activity 1.97025592796299 bayes_pls_golite062009
molecular transducer activity 1.97025592796299 bayes_pls_golite062009
protein binding 1.95763087285706 bayes_pls_golite062009
receptor activity 1.7532159500599 bayes_pls_golite062009
transmembrane receptor activity 1.72393003840462 bayes_pls_golite062009
phosphoinositide 3-kinase binding 1.71957805451003 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.55414958698765 bayes_pls_golite062009
protein kinase activity 1.53914015577029 bayes_pls_golite062009
kinase activity 1.52393509273639 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.39413069155432 bayes_pls_golite062009
transporter activity 1.29925758003665 bayes_pls_golite062009
insulin receptor binding 1.24159469960645 bayes_pls_golite062009
receptor binding 1.17585427851367 bayes_pls_golite062009
transferase activity 1.09391396934652 bayes_pls_golite062009
enzyme binding 0.986198119454688 bayes_pls_golite062009
insulin-like growth factor receptor binding 0.902696448574164 bayes_pls_golite062009
receptor signaling protein activity 0.830314446783898 bayes_pls_golite062009
kinase binding 0.829679711601002 bayes_pls_golite062009
substrate-specific transporter activity 0.807688160227952 bayes_pls_golite062009
SH2 domain binding 0.77769334991472 bayes_pls_golite062009
protein domain specific binding 0.650240628628722 bayes_pls_golite062009
protein serine/threonine kinase activity 0.62326150960884 bayes_pls_golite062009
protein kinase binding 0.557283580441975 bayes_pls_golite062009
actin filament binding 0.516969879010319 bayes_pls_golite062009
transcription regulator activity 0.462744818503729 bayes_pls_golite062009
protein complex binding 0.424439033593144 bayes_pls_golite062009
nucleic acid binding 0.42289557002454 bayes_pls_golite062009
DNA binding 0.362931880290478 bayes_pls_golite062009
structure-specific DNA binding 0.358136502761366 bayes_pls_golite062009
structural molecule activity 0.332112521019418 bayes_pls_golite062009
GTPase regulator activity 0.191468082618045 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.183587483764957 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 0.174772802535455 bayes_pls_golite062009
enzyme regulator activity 0.0687306550834211 bayes_pls_golite062009
pyrophosphatase activity 0.0123738509852108 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0042696817373139 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.00109440156897189 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [412-722]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DNAEQALEFA NLYQVLSDKT LGSGQFGTVY SAIQRHSGKE VAVKVISKER FSKKGSGAES  60
   61 MRAEVAILQQ TCHPGIVCLE FMCETKDKIF VVMEKMNGDM LEMILSQELG RLNSRATKFL 120
  121 LVQILCALKY LHDQGIAHCD LKPENVLLSD MGSNFPQTKI CDFGYARFIP ESQFRKTVVG 180
  181 TPAYLPPEVL QRKGYNKSLD MWSVGVIIYV TLSGTFPFNE GEEISEQIQN ASFMFPTEPW 240
  241 SEVEPLAVDL IQKLLKVEIE ARMSIEQCLD HGWLKGEQLY RDLRDLEVRL NTPRYLTSPQ 300
  301 DDILYGTLVN P

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 64.30103
Match: 2cn5A
Description: No description for 2cn5A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle