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View Structure Prediction Details

Protein: CE08773
Organism: Caenorhabditis elegans
Length: 459 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE08773.

Description E-value Query
Range		 Subject
Range
gi|71062053, gi|... - gi|71082940|ref|YP_265659.1| dihydrolipoyl dehydrogenase [Candidatus Pelagibacter ubique HTCC1062], ...
 399.0 [0..1] [458..1]

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Predicted Domain #1
Region A:
Residues: [1-459] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGVKEFDYL VIGGGSGGIA SARRAREFGV SVGLIESGRL GGTCVNVGCV PKKVMYNCSL  60
   61 HAEFIRDHAD YGFDVTLNKF DWKVIKKSRD EYIKRLNGLY ESGLKGSSVE YIRGRATFAE 120
  121 DGTVEVNGAK YRGKNTLIAV GGKPTIPNIK GAEHGIDSDG FFDLEDLPSR TVVVGAGYIA 180
  181 VEIAGVLANL GSDTHLLIRY DKVLRTFDKM LSDELTADMD EETNPLHLHK NTQVTEVIKG 240
  241 DDGLLTIKTT TGVIEKVQTL IWAIGRDPLT KELNLERVGV KTDKSGHIIV DEYQNTSAPG 300
  301 ILSVGDDTGK FLLTPVAIAA GRRLSHRLFN GETDNKLTYE NIATVVFSHP LIGTVGLTEA 360
  361 EAVEKYGKDE VTLYKSRFNP MLFAVTKHKE KAAMKLVCVG KDEKVVGVHV FGVGSDEMLQ 420
  421 GFAVAVTMGA TKKQFDQTVA IHPTSAEELV TMRGGVKPE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 98.69897
Match: 1grtA
Description: HUMAN GLUTATHIONE REDUCTASE A34E/R37W MUTANT
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
pyruvate dehydrogenase activity 8.42473605174108 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor 8.07008457237017 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 7.86778387378753 bayes_pls_golite062009
dihydrolipoyl dehydrogenase activity 7.84550673347799 bayes_pls_golite062009
lipoamide binding 7.21320397413054 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor 6.68894387221662 bayes_pls_golite062009
pyruvate dehydrogenase (acetyl-transferring) activity 6.56425883527182 bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity 6.2758493127081 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 6.2758493127081 bayes_pls_golite062009
oxoglutarate dehydrogenase (succinyl-transferring) activity 5.32373368820399 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 4.48151296542899 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 4.19923051777224 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 4.05603184984386 bayes_pls_golite062009
antioxidant activity 3.99666840824738 bayes_pls_golite062009
oxidoreductase activity 3.78622758776028 bayes_pls_golite062009
NADH dehydrogenase activity 3.68406278988218 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 3.50748163367583 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 3.23754178295825 bayes_pls_golite062009
oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor 3.15456908604913 bayes_pls_golite062009
thioredoxin-disulfide reductase activity 3.04300775355641 bayes_pls_golite062009
glutathione binding 2.84679371365652 bayes_pls_golite062009
glutathione-disulfide reductase activity 2.72350669229836 bayes_pls_golite062009
oxidoreductase activity, oxidizing metal ions 2.49798084628282 bayes_pls_golite062009
tubulin binding 2.40546880499445 bayes_pls_golite062009
catalytic activity 2.35839632763616 bayes_pls_golite062009
microtubule binding 2.30064869971937 bayes_pls_golite062009
cytoskeletal protein binding 2.23446140524739 bayes_pls_golite062009
peptide disulfide oxidoreductase activity 2.13269617402519 bayes_pls_golite062009
glutathione disulfide oxidoreductase activity 2.13269617402519 bayes_pls_golite062009
disulfide oxidoreductase activity 1.87417564758524 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors 1.71836807554864 bayes_pls_golite062009
binding 1.50672625307126 bayes_pls_golite062009
oxygen-dependent protoporphyrinogen oxidase activity 1.42994468012845 bayes_pls_golite062009
protein binding 1.21627488765992 bayes_pls_golite062009
transporter activity 1.16027171869703 bayes_pls_golite062009
transmembrane transporter activity 1.04563737396213 bayes_pls_golite062009
substrate-specific transporter activity 0.992020263296138 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.886337714694097 bayes_pls_golite062009
ion transmembrane transporter activity 0.795364404071999 bayes_pls_golite062009
cation transmembrane transporter activity 0.718226588475577 bayes_pls_golite062009
NADPH-adrenodoxin reductase activity 0.684108511779641 bayes_pls_golite062009
transferase activity 0.649374189439191 bayes_pls_golite062009
electron carrier activity 0.511623955786613 bayes_pls_golite062009
succinate dehydrogenase activity 0.110826254138262 bayes_pls_golite062009
coenzyme binding 0.10945648874523 bayes_pls_golite062009
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