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Catalysis of an oxidation-reduction (redox) reaction that interconverts reduced sulfide groups and oxidized disulfide bonds in a substrate. Catalysis of the reaction: a peptide with reduced sulfide groups = a peptide with oxidized disulfide bonds. Catalysis of the reaction: 2 glutathione + electron acceptor = glutathione disulfide + electron donor. Catalysis of the reaction: 2 glutathione + dehydroascorbate = glutathione disulfide + ascorbate. Catalysis of the reaction: 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: glutathione disulfide oxidoreductase activity
Acc: GO:0015038
Aspect: Molecular Function
Desc: Catalysis of the reaction: 2 glutathione + electron acceptor = glutathione disulfide + electron donor.
Synonyms:
  • glutathione disulphide oxidoreductase activity
  • glutaredoxin
Proteins in PDR annotated with:
   This term: 4 [Search]
   Term or descendants: 37 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0015038 - glutathione disulfide oxidoreductase activity (interactive image map)
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