YRC Public Data Repository - Protein Structure Prediction

Protein:	CE03132
Organism:	Caenorhabditis elegans
Length:	278 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE03132.

Description	E-value	Query Range	Subject Range
FABG_THEMA - 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Thermotoga maritima GN=fabG PE=3 SV=1 FABG_THEMA - 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / D...	277.0	[0..4]	[266..2]
gi\|146296617, gi... - gi\|82501013\|ref\|ZP_00886394.1\| 3-oxoacyl-(acyl-carrier-protein) reductase [Caldicellulosiruptor sacc...	274.0	[0..5]	[266..4]
gi\|18310052, gi\|... - gi\|18310052\|ref\|NP_561986.1\| 3-ketoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens st...	273.0	[0..5]	[266..2]
gi\|53688164 - gi\|53688164\|ref\|ZP_00110036.2\| COG1028: Dehydrogenases with different specificities (related to shor...	270.0	[0..2]	[266..106]
gi\|168210762, gi... - gi\|170711222\|gb\|EDT23404.1\| 3-oxoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens B st... gi\|110675446, gi... - gi\|110800799\|ref\|YP_695772.1\| 3-ketoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens A... gi\|170660709, gi... - gi\|170660709\|gb\|EDT13392.1\| 3-oxoacyl- reductase [Clostridium perfringens E str. JGS1987], gi\|168207...	270.0	[0..5]	[266..2]
gi\|115250215, gi... - gi\|126698778\|ref\|YP_001087675.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile 6... gi\|255306086 - gi\|255306086\|ref\|ZP_05350258.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile AT... gi\|255100197 - gi\|255100197\|ref\|ZP_05329174.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC...	268.0	[0..4]	[266..3]
gi\|255313843 - gi\|255313843\|ref\|ZP_05355426.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255516524 - gi\|255516524\|ref\|ZP_05384200.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255649624 - gi\|255649624\|ref\|ZP_05396526.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|254974717 - gi\|254974717\|ref\|ZP_05271189.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255092105 - gi\|255092105\|ref\|ZP_05321583.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile CI... gi\|90575404, gi\|... - gi\|90575404\|ref\|ZP_01231888.1\| hypothetical protein CdifQ_02001165 [Clostridium difficile QCD-32g58]...	268.0	[0..4]	[266..3]
gi\|89098688, gi\|... - gi\|89098688\|ref\|ZP_01171570.1\| beta-ketoacyl-acyl carrier protein reductase [Bacillus sp. NRRL B-149...	268.0	[0..4]	[266..2]
gi\|110803752, gi... - gi\|110803752\|ref\|YP_698460.1\| 3-ketoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens S...	268.0	[0..5]	[266..2]
gi\|172056254, gi... - gi\|68056277\|ref\|ZP_00540404.1\| Short-chain dehydrogenase/reductase SDR [Exiguobacterium sibiricum 25...	264.0	[0..1]	[275..1]

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Predicted Domain #1

Region A:
Residues: [1-278]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKRFSKKVA IITGSSSGIG RETALLFAKE GAKVTVTGRS EEKLEETKKA LLDAGIKESN  60
   61 FLIVPADITF STGQDELISQ TLKKFGRINI LVNNAGASIP DAKKRTGIDQ GIETYEQVMK 120
  121 LNVQSVIEMT QKVRPHLAKS RGEIVNVSSV VALKAGWTRT PYYPLAKAAL DQYTRSAAIA 180
  181 LISEGIRVNT VNPGIVQTGF QANASGSSSD DAQKFYDDMG SNTTAIPCGF AGRPEHIAKA 240
  241 IAFLADRNSS EYIVGQNIIA DGGTSLVLGI HGPAGGKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	65.69897
Match:	1spxA
Description:	Crystal Structure of Glucose Dehydrogenase of Caenorhabditis Elegans in the Apo-Form
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
retinol dehydrogenase activity	4.1750549780559	bayes_pls_golite062009
oxidoreductase activity	3.09625241707629	bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity	3.06391460989761	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	3.02758902218302	bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity	2.94416173750168	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	2.344389379767	bayes_pls_golite062009
ethanol binding	2.01597876952325	bayes_pls_golite062009
retinol binding	1.92497267707609	bayes_pls_golite062009
catalytic activity	1.79741889688267	bayes_pls_golite062009
steroid dehydrogenase activity	1.75109362865449	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.65338499044318	bayes_pls_golite062009
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.55012034958204	bayes_pls_golite062009
alcohol binding	1.51091775360793	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.47309297191111	bayes_pls_golite062009
fatty acid synthase activity	1.23679054027553	bayes_pls_golite062009
sorbose reductase activity	1.06293597394863	bayes_pls_golite062009
benzaldehyde dehydrogenase activity	1.05577641583555	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	1.01627645289834	bayes_pls_golite062009
binding	0.982999356179965	bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent	0.839863523675468	bayes_pls_golite062009
retinal dehydrogenase activity	0.69372321031969	bayes_pls_golite062009
3-oxoacyl-[acyl-carrier-protein] reductase activity	0.604742541607263	bayes_pls_golite062009
3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity	0.583772223704381	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	0.576163737662951	bayes_pls_golite062009
testosterone 17-beta-dehydrogenase activity	0.532187027260366	bayes_pls_golite062009
DNA binding	0.525227236870065	bayes_pls_golite062009
all-trans retinal binding	0.522435200991921	bayes_pls_golite062009
nucleic acid binding	0.459537641913493	bayes_pls_golite062009
enoyl-CoA hydratase activity	0.439912268968251	bayes_pls_golite062009
NADPH:quinone reductase activity	0.417492617930618	bayes_pls_golite062009
transcription regulator activity	0.177044638410302	bayes_pls_golite062009
methylenetetrahydrofolate dehydrogenase activity	0.124826575912808	bayes_pls_golite062009
methenyltetrahydrofolate cyclohydrolase activity	0.118312276550651	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.0913823272876781	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: