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View Structure Prediction Details

Protein: SPAP8A3.05
Organism: Schizosaccharomyces pombe
Length: 695 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAP8A3.05.

Description E-value Query
Range
Subject
Range
EF1A_CHICK - Elongation factor 1-alpha 1 OS=Gallus gallus GN=EEF1A PE=2 SV=1
484.0 [0..274] [693..1]
EF11_MOUSE - (P10126) Elongation factor 1-alpha 1 (EF-1-alpha-1) (Elongation factor 1 A-1) (eEF1A-1) (Elongation ...
483.0 [0..274] [693..1]
gi|15805031, gi|... - gi|15805031|ref|NP_284925.1| eukaryotic translation elongation factor 1 alpha 2 [Rattus norvegicus],...
483.0 [0..274] [693..1]
gi|62896661 - gi|62896661|dbj|BAD96271.1| eukaryotic translation elongation factor 1 alpha 1 variant [Homo sapiens...
483.0 [0..274] [693..1]
gi|60830534 - gi|60830534|gb|AAX36933.1| eukaryotic translation elongation factor 1 alpha 1 [synthetic construct]
483.0 [0..274] [693..1]
gi|163915877, gi... - gi|62859813|ref|NP_001016692.1| eukaryotic translation elongation factor 1 alpha 1 [Xenopus (Siluran...
482.0 [0..274] [693..1]

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Predicted Domain #1
Region A:
Residues: [1-267]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRLSQLLNS KKAKQKPPSE HPIGLSSILK QDSSSSSDSP NFFPSSSTND HQERDTINDT  60
   61 NFVVPEKQKT SKLALLAAER KKLHSSFPST QQQPPKTEKE KEKEPIQAKH KKNVENDFLL 120
  121 QRFRKVRIAE KKDSEQPSSH EIHLTDDDDK TTLQKQMVES DQLKKNPQEV KLAPPSSFAK 180
  181 CLTGAKKRVF EDQIEIHLSK SSLLGFNAPS PDDIVLMAQS KSKSFQKHKR LDEQLLNSVK 240
  241 SMKKVSQQLK PQKNTNDSNN DHTLLSQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.0
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [268-695]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DQLIELSKLV KPRTKLLLLG PPKSGKKTLL SRLFFQIGSF DPKTMQKCTV LNAKKESLSS  60
   61 VLKSTKTKWY DFETFSNSYS STIIDFPLGI FTTNASSRDN FLKHSSLFQV MNTAIFTIDC 120
  121 LNPLEGLDGI SSILQLMNGL SISSYMFAIT KMDEIEWDEN KFINLVNSIQ SFLKESCGII 180
  181 EKSKFIPISG LKGTNLTSIS QEKLSQWYKS DTLLGKIDKE ADTNHGTWNF LLNLPLSLTI 240
  241 SHITPLPENQ SHIYCSIHSG MLQDSQKLYV GTGRLETQIT GLSSDENPKG FNVAGDMIQA 300
  301 KIPTLPNLCP GILIADSIDA FTSSKTAYVN ATWFHGSLEK GKSMHVIALF GCHAVLTKLY 360
  361 CFTDSQEKAP NAIGNDLERN RTSLVKIELE NAFPLVKESY INTLSRVLFV SEKWNSLIAF 420
  421 GTVLSLHD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 133.0
Match: 1f60A
Description: Elongation factor eEF-1alpha, domain 2; Elongation factor eEF-1alpha, C-terminal domain; Elongation factor eEF-1alpha, N-terminal (G) domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ribonuclease activity 4.3040603813219 bayes_pls_golite062009
hydrolase activity 2.55157966585974 bayes_pls_golite062009
binding 2.05253348982328 bayes_pls_golite062009
nucleic acid binding 1.60768715809391 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1.44266227866728 bayes_pls_golite062009
exonuclease activity 1.15670533472751 bayes_pls_golite062009
DNA binding 1.11699929651302 bayes_pls_golite062009
nuclease activity 1.06224744208356 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
transcription regulator activity 0.989226939888218 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.759324158861044 bayes_pls_golite062009
RNA binding 0.715902454627085 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.546796591575762 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.543610140926125 bayes_pls_golite062009
pyrophosphatase activity 0.540750418412449 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.517457589081898 bayes_pls_golite062009
0.3172470686972 bayes_pls_golite062009
nucleotide binding 0.114848452385726 bayes_pls_golite062009
purine nucleotide binding 0.10713474095071 bayes_pls_golite062009
purine ribonucleotide binding 0.0916519414118148 bayes_pls_golite062009
ribonucleotide binding 0.0915913646217636 bayes_pls_golite062009
helicase activity 0.0775311459068899 bayes_pls_golite062009
transcription factor activity 0.0434163635422169 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle