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View Structure Prediction Details

Protein: prp11
Organism: Schizosaccharomyces pombe
Length: 1014 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for prp11.

Description E-value Query
Range		 Subject
Range
PRP5_GIBZE - Pre-mRNA-processing ATP-dependent RNA helicase PRP5 OS=Gibberella zeae GN=PRP5 PE=3 SV=1
PRP5_GIBZE - Pre-mRNA-processing ATP-dependent RNA helicase PRP5 OS=Gibberella zeae (strain PH-1 / ATCC MYA-4620 ...
 462.0 [0..5] [1013..165]
PRP5_EMENI - Pre-mRNA-processing ATP-dependent RNA helicase prp5 OS=Emericella nidulans GN=prp5 PE=3 SV=1
PRP5_EMENI - Pre-mRNA-processing ATP-dependent RNA helicase prp5 OS=Emericella nidulans (strain FGSC A4 / ATCC 38...
 435.0 [0..68] [1014..169]
PRP5_NEUCR - Pre-mRNA-processing ATP-dependent RNA helicase prp-5 OS=Neurospora crassa GN=prp-5 PE=3 SV=1
PRP5_NEUCR - Pre-mRNA-processing ATP-dependent RNA helicase prp-5 OS=Neurospora crassa (strain ATCC 24698 / 74-OR...
 425.0 [0..188] [1013..332]
PRP5_COCIM - Pre-mRNA-processing ATP-dependent RNA helicase PRP5 OS=Coccidioides immitis (strain RS) GN=PRP5 PE=3...
PRP5_COCIM - Pre-mRNA-processing ATP-dependent RNA helicase PRP5 OS=Coccidioides immitis GN=PRP5 PE=3 SV=1
 422.0 [0..12] [1014..151]
PRP5_ASPOR - Pre-mRNA-processing ATP-dependent RNA helicase prp5 OS=Aspergillus oryzae (strain ATCC 42149 / RIB 4...
PRP5_ASPOR - Pre-mRNA-processing ATP-dependent RNA helicase prp5 OS=Aspergillus oryzae GN=prp5 PE=3 SV=1
 422.0 [0..6] [1014..132]
PRP5_ASPTN - Pre-mRNA-processing ATP-dependent RNA helicase prp5 OS=Aspergillus terreus (strain NIH 2624 / FGSC A...
 419.0 [0..21] [1014..132]
PRP5_ASPFU - Pre-mRNA-processing ATP-dependent RNA helicase prp5 OS=Neosartorya fumigata (strain ATCC MYA-4609 / ...
PRP5_ASPFU - Pre-mRNA-processing ATP-dependent RNA helicase prp5 OS=Aspergillus fumigatus GN=prp5 PE=3 SV=1
 419.0 [0..275] [1014..426]
gi|218200507 - gi|218200507|gb|EEC82934.1| hypothetical protein OsI_27901 [Oryza sativa Indica Group]
RH42_ORYSJ - DEAD-box ATP-dependent RNA helicase 42 OS=Oryza sativa subsp. japonica GN=Os08g0159900 PE=2 SV=1
 411.0 [0..178] [1014..170]
PRP5_CHAGB - Pre-mRNA-processing ATP-dependent RNA helicase PRP5 OS=Chaetomium globosum GN=PRP5 PE=3 SV=1
PRP5_CHAGB - Pre-mRNA-processing ATP-dependent RNA helicase PRP5 OS=Chaetomium globosum (strain ATCC 6205 / CBS 1...
 404.0 [0..245] [1013..252]
gi|39944782, gi|... - gi|39944782|ref|XP_361928.1| hypothetical protein MG04373.4 [Magnaporthe grisea 70-15], gb|EAA50614....
 400.0 [0..330] [1013..508]

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Predicted Domain #1
Region A:
Residues: [1-238] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRRTRSRSP PRRSYNRERR DYRKYDDSED QKGARYNRYV DDVSSRRDRH DSFRSHESNK  60
   61 IRRDNSWKHD KYSYEKRYQE RDREYARSKN IPDQYIGRSP RPTSHRHAEE KEVDNKTKSD 120
  121 ETNPVLQGSA TEIKPQPRRS RFDRTERVGA SLSVSEIQSE NPRVDVIPKD KAVENNHQRN 180
  181 AEKPVASDKI TDAKLLARLE RVRAWKESKA KQEASKKEEH KLNTKPQVTA KDQNAMPS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [239-359] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGISGFEINR QKDTSDMKRN NRVHMDDEDG PRRMNLEDYQ ELWDQEDRGM LGNEQAASME  60
   61 EDEVDPLDAY MASLVGTTDT IRPGLLNTEV IDPNANDDER MVISETLEEE ENLLALAAKR 120
  121 S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [360-437] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKKDVITVDH SKINYEDFKK DFYVEPEELK NLSPAEVDEL RASLDGIKIR GIDCPKPVTS  60
   61 WSQCGLSAQT ISVINSLG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.05
Match: 2db3A
Description: No description for 2db3A was found.

Predicted Domain #4
Region A:
Residues: [438-897] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YEKPTSIQAQ AIPAITSGRD VIGVAKTGSG KTIAFLLPMF RHIKDQRPLK TGEGPIAIIM  60
   61 TPTRELAVQI FRECKPFLKL LNIRACCAYG GAPIKDQIAD LKRGAEIVVC TPGRMIDVLS 120
  121 ANAGRVTNLH RCTYLVLDEA DRMFDLGFEP QVMRIINNIR PDRQTVLFSA TFPRAMEALA 180
  181 RKVLKKPVEI TVGGRSVVAS EVEQIVEVRP EESKFSRLLE LLGELYNNQL DVRTLVFVDR 240
  241 QESADALLSD LMKRGYTSNS IHGGKDQHDR DSTISDYKAG VFDVLIATSV VARGLDVKSL 300
  301 QLVVNYDCPN HMEDYVHRVG RTGRAGHTGV AVTFITPEQE KYAVDIAKAL KMSKQPVPKE 360
  361 LQTLASQFLE KVKAGKEKAA GGGFGGKGLS RLDETRNAER KMQRKAYGED EEDVETEAEA 420
  421 KSPLEKITPE KSTGDPTLDR VRAAVGGIAA RAFANQTAQS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.69897
Match: 2v8oA
Description: No description for 2v8oA was found.

Predicted Domain #5
Region A:
Residues: [898-1014] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKLTQPISII KTDGDEYKAK MEINDYPQQA RWAVTNNTNI VHVTELTGTS ITTKGNFYLP  60
   61 GKNPEPGEEK LYLWIEGPSE LVVNRAITEL RRLLLEGINH SLEGGNKPSA SGRYTVV

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.89
Match: 1k1gA
Description: RNA splicing factor 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.35205331138538 bayes_pls_golite062009
4.77327442333813 bayes_pls_golite062009
mRNA binding 4.67566555881601 bayes_pls_golite062009
nucleic acid binding 4.53130750638836 bayes_pls_golite062009
translation factor activity, nucleic acid binding 3.73042056823822 bayes_pls_golite062009
translation regulator activity 3.73023228922019 bayes_pls_golite062009
binding 3.31439627344982 bayes_pls_golite062009
transcription regulator activity 2.52775059206789 bayes_pls_golite062009
DNA binding 2.19723508219193 bayes_pls_golite062009
protein binding 2.14744035029318 bayes_pls_golite062009
transcription repressor activity 1.98431295251845 bayes_pls_golite062009
structure-specific DNA binding 1.87570901607985 bayes_pls_golite062009
single-stranded DNA binding 1.84702374199408 bayes_pls_golite062009
hydrolase activity 1.79430008755254 bayes_pls_golite062009
poly-pyrimidine tract binding 1.75736205236351 bayes_pls_golite062009
transcription activator activity 1.69164969753194 bayes_pls_golite062009
transcription factor activity 1.23593912870728 bayes_pls_golite062009
sequence-specific DNA binding 1.11206973049533 bayes_pls_golite062009
ribonuclease activity 0.925909354724523 bayes_pls_golite062009
signal transducer activity 0.820828954646689 bayes_pls_golite062009
molecular transducer activity 0.820828954646689 bayes_pls_golite062009
single-stranded RNA binding 0.795008427109843 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.684269812564476 bayes_pls_golite062009
mRNA 3'-UTR binding 0.370287528838428 bayes_pls_golite062009
transcription factor binding 0.227610374185311 bayes_pls_golite062009
exoribonuclease activity 0.150228013820667 bayes_pls_golite062009
catalytic activity 0.1435046019283 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 0.110425673333101 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle