YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC343.15
Organism:	Schizosaccharomyces pombe
Length:	434 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC343.15.

Description	E-value	Query Range	Subject Range
gi\|30048434 - gi\|30048434\|gb\|AAH51040.1\| Trit1 protein [Mus musculus]	416.0	[0..4]	[419..20]
gi\|62898688 - gi\|62898688\|dbj\|BAD97198.1\| tRNA isopentenyltransferase 1 variant [Homo sapiens]	414.0	[0..4]	[419..24]
gi\|109477172, gi... - gi\|62649589\|ref\|XP_342906.2\| PREDICTED: similar to tRNA isopentenyltransferase 1 [Rattus norvegicus]...	413.0	[0..4]	[419..24]
gi\|114555763 - gi\|114555763\|ref\|XP_513347.2\| PREDICTED: tRNA isopentenyltransferase 1 isoform 4 [Pan troglodytes]	411.0	[0..4]	[419..24]
orf19.4801, orf1... - orf19.4801 CGDID:CAL0005287 Assembly 19, Contig19-10215 (184814, 186211) CDS, translated using codon... gi\|46445521, gi\|... - gi\|68465196\|ref\|XP_723297.1\| likely tRNA isopentenyltransferase [Candida albicans SC5314], gi\|684648...	410.0	[0..2]	[430..20]
gi\|109002473 - gi\|109002473\|ref\|XP_001113925.1\| PREDICTED: similar to tRNA isopentenyltransferase 1 isoform 3 [Maca... gi\|90076060 - gi\|90076060\|dbj\|BAE87710.1\| unnamed protein product [Macaca fascicularis]	409.0	[0..4]	[419..24]
gi\|151945358 - gi\|151945358\|gb\|EDN63601.1\| tRNA isopentenyltransferase [Saccharomyces cerevisiae YJM789] MOD5 - Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase, required for biosynthesis of the mod... MOD5_YEAST - tRNA dimethylallyltransferase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c...	405.0	[0..1]	[422..12]
gi\|73976757 - gi\|73976757\|ref\|XP_532548.2\| PREDICTED: similar to tRNA isopentenyltransferase 1 isoform 1 [Canis fa...	405.0	[0..4]	[419..24]

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Predicted Domain #1

Region A:
Residues: [1-324]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKPLCVVIG TTGAGKSDLA VQLAKRFGSQ VINADSMQIY RGFDTITNKI TVEEQENVHH  60
   61 RLMSFLNFDK EYSVPEFERD ASRVIDEIHS QGKIPIVVGG THYYLQSLLF EDTTLSAIDK 120
  121 LTNDSSPSKP PHPDSHILDD DPSAMLSYLK KIDPVMAEQW HPRDTRKIRR SLEIYFHTGR 180
  181 PPSEIYSEQK MKSSGSKLRY KSLIFWAFAD SLVLMPRLDK RVDKMLSHGL VDEIKSMKSL 240
  241 AESEKFSPDF TRGIWQCIGF KEFMPWFEAP SDIVFNDCLE RMKVSTRQYA KSQKKWIQSR 300
  301 FLPMCLAQQD LSPSSILFST TNTT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	110.0
Match:	2qgnA
Description:	No description for 2qgnA was found.

Predicted Domain #2

Region A:
Residues: [325-434]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLNNWEEQVE KACRVFQYFF YNGDAIAPSA DDQHAFEKAR DYLSIMNGRQ SQKKKFVCEE  60
   61 CLDKRGDPFT VIGEDAFNVH IKSRKHKTTV RRKKERAERQ IRLKNIGILK

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.9
Match:	1zr9A
Description:	Solution Structure of a Human C2H2-type Zinc Finger Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	3.37529385176635	bayes_pls_golite062009
DNA binding	3.3049326844117	bayes_pls_golite062009
nucleic acid binding	3.24981360535232	bayes_pls_golite062009
transcription factor activity	2.44389510173662	bayes_pls_golite062009
binding	2.40458515823407	bayes_pls_golite062009
RNA polymerase II transcription factor activity	1.57041104288348	bayes_pls_golite062009
transcription activator activity	1.20323819132961	bayes_pls_golite062009
protein binding	0.936302453256998	bayes_pls_golite062009
RNA binding	0.84315767580466	bayes_pls_golite062009
sequence-specific DNA binding	0.732558534458316	bayes_pls_golite062009
transcription repressor activity	0.686318575498149	bayes_pls_golite062009
chromatin binding	0.626365497850853	bayes_pls_golite062009
transcription factor binding	0.515821187939278	bayes_pls_golite062009
catalytic activity	0.263007611601737	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	0.200483461579207	bayes_pls_golite062009
transcription cofactor activity	0.113925660147477	bayes_pls_golite062009
structure-specific DNA binding	0.0855506955761403	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: