YRC Public Data Repository - Protein Structure Prediction

Protein:	SPCC965.06
Organism:	Schizosaccharomyces pombe
Length:	344 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPCC965.06.

Description	E-value	Query Range	Subject Range
gi\|56420510, gi\|... - gi\|56420510\|ref\|YP_147828.1\| K+ channel beta subunit [Geobacillus kaustophilus HTA426], gi\|56380352\|...	321.0	[0..13]	[334..1]
gi\|53765455, gi\|... - gi\|75906333\|ref\|YP_320629.1\| aldo/keto reductase [Anabaena variabilis ATCC 29413], gi\|75700058\|gb\|AB...	318.0	[0..13]	[338..2]
gi\|159893771, gi... - gi\|159900732\|ref\|YP_001546979.1\| aldo/keto reductase [Herpetosiphon aurantiacus ATCC 23779], gi\|1598...	315.0	[0..13]	[334..1]
gi\|33596263 - gi\|33596263\|ref\|NP_883906.1\| putative oxidoreductase [Bordetella parapertussis 12822] gi\|33573266 - gi\|33573266\|emb\|CAE36928.1\| putative oxidoreductase [Bordetella parapertussis]	314.0	[0..13]	[338..1]
gi\|33602077, gi\|... - gi\|33602077\|ref\|NP_889637.1\| putative oxidoreductase [Bordetella bronchiseptica RB50], gi\|33576515\|e...	314.0	[0..13]	[338..1]
gi\|76166661, gi\|... - gi\|76258577\|ref\|ZP_00766232.1\| Aldo/keto reductase [Chloroflexus aurantiacus J-10-fl], gi\|76166661\|g... gi\|222524644, gi... - gi\|222524644\|ref\|YP_002569115.1\| aldo/keto reductase [Chloroflexus sp. Y-400-fl], gi\|222448523\|gb\|AC...	313.0	[0..13]	[338..1]
gi\|51892845, gi\|... - gi\|51892845\|ref\|YP_075536.1\| oxidoreductase [Symbiobacterium thermophilum IAM 14863], gi\|51856534\|db...	313.0	[0..13]	[336..1]
gi\|33592063, gi\|... - gi\|33592063\|ref\|NP_879707.1\| putative oxidoreductase [Bordetella pertussis Tohama I], gi\|33571707\|em...	312.0	[0..13]	[338..1]
gi\|46399818, gi\|... - gi\|46446177\|ref\|YP_007542.1\| MocA family oxidoreductase [Candidatus Protochlamydia amoebophila UWE25...	311.0	[0..13]	[344..1]
gi\|50119681, gi\|... - gi\|50119681\|ref\|YP_048848.1\| putative aldo/keto reductase [Pectobacterium atrosepticum SCRI1043], gi...	311.0	[0..13]	[344..1]

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Predicted Domain #1

Region A:
Residues: [1-344]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASATTHFQP KNVPFRFLGR SGLKVSAFSL GGWLTYGNEG YDVEHTKNCL KQAWDLGINT  60
   61 FDTAEIYSNG NSETVMGKAI KELGWDRSEY VITTKVFFGA GTKLPNTTGL SRKHIIEGLN 120
  121 ASLKRLGLPY VDVIMAHRPD PSVPMEEVVR AFTQLIQDGK AFYWGTSEWS AFEIEHAHHI 180
  181 ATKYNLIAPV ADQPQYNYLT RDHFEKDLLP LQQIYGYGAT VWSPLKSGIL TGKYNDGIPE 240
  241 GSRLSTTFTS LAGQLQTPEG KTQLDQVRQI SKIAEQIGAT PSQLALAWTL KNPYVSTTIL 300
  301 GASKPEQIVE NVKAVEFIDK LTPEILKKID EILNFTPLEI QYRR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	78.69897
Match:	1exbA
Description:	Voltage-dependent K+ channel beta subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
potassium channel activity	7.51963276589303	bayes_pls_golite062009
voltage-gated potassium channel activity	7.40239094355354	bayes_pls_golite062009
voltage-gated cation channel activity	6.67507110634301	bayes_pls_golite062009
metal ion transmembrane transporter activity	6.588881463055	bayes_pls_golite062009
voltage-gated ion channel activity	6.52286930358188	bayes_pls_golite062009
voltage-gated channel activity	6.50716590143831	bayes_pls_golite062009
cation channel activity	5.72172645555113	bayes_pls_golite062009
ion channel activity	5.15119282480682	bayes_pls_golite062009
channel activity	5.07214658557001	bayes_pls_golite062009
passive transmembrane transporter activity	5.07214658557001	bayes_pls_golite062009
aldehyde reductase activity	5.07106269693426	bayes_pls_golite062009
substrate-specific channel activity	5.02503292701043	bayes_pls_golite062009
gated channel activity	4.92848832197692	bayes_pls_golite062009
arabinose reductase activity	3.28910924444005	bayes_pls_golite062009
xylose reductase activity	3.28910924444005	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	2.72342789448248	bayes_pls_golite062009
glucose 1-dehydrogenase (NADP+) activity	2.68048267823456	bayes_pls_golite062009
ion transmembrane transporter activity	2.63772951680109	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2.62743427046359	bayes_pls_golite062009
cation transmembrane transporter activity	2.58068601897668	bayes_pls_golite062009
aldo-keto reductase activity	2.57303336304449	bayes_pls_golite062009
aryl-alcohol dehydrogenase activity	2.5168190536972	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.46488926936937	bayes_pls_golite062009
catalytic activity	1.68179794468736	bayes_pls_golite062009
glucose 1-dehydrogenase activity	1.55697325009049	bayes_pls_golite062009
transporter activity	1.24767072239634	bayes_pls_golite062009
binding	1.15657176144267	bayes_pls_golite062009
transmembrane transporter activity	1.03420335553507	bayes_pls_golite062009
potassium channel regulator activity	1.03017249802223	bayes_pls_golite062009
oxidoreductase activity	0.91523123890256	bayes_pls_golite062009
substrate-specific transporter activity	0.783004917746429	bayes_pls_golite062009
protein binding	0.220529867719707	bayes_pls_golite062009
3-alpha-hydroxysteroid dehydrogenase (B-specific) activity	0.207008954325429	bayes_pls_golite062009
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity	0.207008954325429	bayes_pls_golite062009
	0.139676323362391	bayes_pls_golite062009
channel regulator activity	0.12154513851913	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: