YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC222.14c
Organism:	Schizosaccharomyces pombe
Length:	762 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC222.14c.

Description	E-value	Query Range	Subject Range
SEY1_EMENI - Protein sey1 OS=Emericella nidulans GN=sey1 PE=3 SV=1 SEY1_EMENI - Protein sey1 OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) GN=...	467.0	[0..2]	[743..12]
SEY1_USTMA - Protein SEY1 OS=Ustilago maydis GN=SEY1 PE=3 SV=1 gi\|49069478, gi\|... - gi\|71005788\|ref\|XP_757560.1\| hypothetical protein UM01413.1 [Ustilago maydis 521], ref\|XP_399028.1\| ...	466.0	[0..11]	[748..153]
SEY1_ASPTN - Protein sey1 OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) GN=sey1 PE=3 SV=1	462.0	[0..2]	[746..12]
gi\|42547583, gi\|... - gi\|46107900\|ref\|XP_381009.1\| hypothetical protein FG00833.1 [Gibberella zeae PH-1], gi\|42547583\|gb\|E...	460.0	[0..10]	[760..21]
gi\|169768782 - gi\|169768782\|ref\|XP_001818861.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83766719 - gi\|83766719\|dbj\|BAE56859.1\| unnamed protein product [Aspergillus oryzae]	460.0	[0..10]	[744..24]
SEY1_NEUCR - Protein sey1 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987... SEY1_NEUCR - Protein sey1 OS=Neurospora crassa GN=sey1 PE=3 SV=1	457.0	[0..10]	[758..27]
SEY1_ASPFC - Protein sey1 OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) GN=sey1 PE=3 SV=1 SEY1_ASPFU - Protein sey1 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) GN=sey... SEY1_ASPFU - Protein sey1 OS=Aspergillus fumigatus GN=sey1 PE=3 SV=1	456.0	[0..10]	[745..23]
SEY1_MAGGR - Protein SEY1 OS=Magnaporthe grisea GN=SEY1 PE=3 SV=1 SEY1_MAGO7 - Protein SEY1 OS=Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) GN=SEY1 PE=3 SV=1	447.0	[0..10]	[754..21]
gi\|169597649, gi... - gi\|169597649\|ref\|XP_001792248.1\| hypothetical protein SNOG_01612 [Phaeosphaeria nodorum SN15], gi\|11...	436.0	[0..1]	[757..34]
SEY1_COCIM - Protein SEY1 OS=Coccidioides immitis (strain RS) GN=SEY1 PE=3 SV=1 SEY1_COCIM - Protein SEY1 OS=Coccidioides immitis GN=SEY1 PE=3 SV=1	430.0	[0..10]	[730..22]

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Predicted Domain #1

Region A:
Residues: [1-529]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTASNRVST QIVDEHKQFN NELPKFMQSV GLLDAGFNYH VVAVLGSQST GKSTLLNNLF  60
   61 GTSFSVMDAS KRQQTTKGIW LSKANNSPIL VMDVEGTDGR ERGEDQDFER KSALFSISTS 120
  121 EVIIVNMWEN QVGLYQGSNM ALLKTVLEVN LQLFHNKKER CLLQFVIRDF LGNTSMENLA 180
  181 DTIMTDLNNI WASLSKPEGF ENSVINDFFD VGFTGLPHKI LCSDAFSEAV DSLRERFVDN 240
  241 NNSDYIFNVS YHKKIPADGF SLYTREIWDT IENNKDLDLP TQQQLLAQYR CDEIITEVME 300
  301 PFSTACTILQ KEFLPGNLCK DLPTKLLNMF ETVIEAYDRQ ASRYNVHIYQ KKKQELIASV 360
  361 DSHLYVFFQA QLNALHKELI KSFFDASNEF PSDTPFKESS SIKINELVNK MREEGESLSL 420
  421 PHVHWDVDPF ILKLSEELTQ NSETLCKEKL KEKLEELFTG FEFEVSEAVE VAFQKLSHNV 480
  481 WDTLLNEFLA AQNTTIEKIK NIVPFYVDID DTKTTEEYII NFKKNSWLF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	58.154902
Match:	1dg3A
Description:	Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain; Interferon-induced guanylate-binding protein 1 (GBP1), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	3.10463051760206	bayes_pls_golite062009
transmembrane transporter activity	2.95886887664984	bayes_pls_golite062009
nucleoside-triphosphatase activity	2.74389108884083	bayes_pls_golite062009
pyrophosphatase activity	2.67097555143215	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	2.65161658635465	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	2.64849912301318	bayes_pls_golite062009
active transmembrane transporter activity	2.50494515048649	bayes_pls_golite062009
primary active transmembrane transporter activity	2.39629638016861	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	2.39600931083427	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	2.36051733655256	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	2.35906629925754	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	2.35679406876731	bayes_pls_golite062009
ATPase activity	2.2625504298178	bayes_pls_golite062009
ATPase activity, coupled	2.24901251684901	bayes_pls_golite062009
binding	2.00548409930693	bayes_pls_golite062009
substrate-specific transporter activity	1.65609907941094	bayes_pls_golite062009
hydrolase activity	1.34710139310747	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.3182108176243	bayes_pls_golite062009
nucleic acid binding	1.24151268097078	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
purine nucleotide binding	0.929901285538132	bayes_pls_golite062009
nucleotide binding	0.922442819194247	bayes_pls_golite062009
purine ribonucleotide binding	0.920987930180051	bayes_pls_golite062009
ribonucleotide binding	0.920926158369519	bayes_pls_golite062009
DNA binding	0.829652732561224	bayes_pls_golite062009
GTPase activity	0.768815888267067	bayes_pls_golite062009
ion transmembrane transporter activity	0.704934361725919	bayes_pls_golite062009
transcription regulator activity	0.648798858522413	bayes_pls_golite062009
ATP binding	0.41092997612902	bayes_pls_golite062009
structural constituent of ribosome	0.396187998943318	bayes_pls_golite062009
drug transmembrane transporter activity	0.38711726712063	bayes_pls_golite062009
adenyl ribonucleotide binding	0.385813421701492	bayes_pls_golite062009
adenyl nucleotide binding	0.377870145186619	bayes_pls_golite062009
translation regulator activity	0.29096092258568	bayes_pls_golite062009
cation transmembrane transporter activity	0.282397764628576	bayes_pls_golite062009
translation factor activity, nucleic acid binding	0.274994961137851	bayes_pls_golite062009
protein binding	0.170837278876362	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [530-653]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FRKKIDSEMS EVLLQQRLRV YFEELFRYDS DGMPKLWKKS GTIDRDYRES LTKTLDLINV  60
   61 LASIKVSDGN YPDLNVDIKT LEPEYTSPAS FFTILNRRRV SDISVNFKRS ADLIFMDCKR 120
  121 SVIN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	15.39794
Match:	1i84S
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [654-762]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTTRIPPYFW VLLIVLGWNE FMAILRNPFV FMILMFGGTV VYGLYISGLI WPAKMVLERA  60
   61 TNNLVDLATD RFSNTYQEQV QQRAMQRTEK SGSPVASADD AEAEKTALS

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	0.954
Match:	2qksA
Description:	No description for 2qksA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: