YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC4G9.15
Organism:	Schizosaccharomyces pombe
Length:	341 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC4G9.15.

Description	E-value	Query Range	Subject Range
gi\|146296617, gi... - gi\|82501013\|ref\|ZP_00886394.1\| 3-oxoacyl-(acyl-carrier-protein) reductase [Caldicellulosiruptor sacc...	266.0	[0..52]	[314..1]
gi\|18310052, gi\|... - gi\|18310052\|ref\|NP_561986.1\| 3-ketoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens st...	264.0	[0..55]	[314..2]
gi\|168210762, gi... - gi\|170711222\|gb\|EDT23404.1\| 3-oxoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens B st... gi\|110675446, gi... - gi\|110800799\|ref\|YP_695772.1\| 3-ketoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens A... gi\|170660709, gi... - gi\|170660709\|gb\|EDT13392.1\| 3-oxoacyl- reductase [Clostridium perfringens E str. JGS1987], gi\|168207...	260.0	[0..55]	[314..2]
gi\|255313843 - gi\|255313843\|ref\|ZP_05355426.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255516524 - gi\|255516524\|ref\|ZP_05384200.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255649624 - gi\|255649624\|ref\|ZP_05396526.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|254974717 - gi\|254974717\|ref\|ZP_05271189.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255092105 - gi\|255092105\|ref\|ZP_05321583.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile CI... gi\|90575404, gi\|... - gi\|90575404\|ref\|ZP_01231888.1\| hypothetical protein CdifQ_02001165 [Clostridium difficile QCD-32g58]...	259.0	[0..52]	[314..1]
gi\|115250215, gi... - gi\|126698778\|ref\|YP_001087675.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile 6... gi\|255306086 - gi\|255306086\|ref\|ZP_05350258.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile AT... gi\|255100197 - gi\|255100197\|ref\|ZP_05329174.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC...	259.0	[0..52]	[314..1]
FABG_THEMA - 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Thermotoga maritima GN=fabG PE=3 SV=1 FABG_THEMA - 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / D...	258.0	[0..54]	[314..2]
gi\|110803752, gi... - gi\|110803752\|ref\|YP_698460.1\| 3-ketoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens S...	257.0	[0..55]	[314..2]
gi\|91184216, gi\|... - gi\|91217712\|ref\|ZP_01254669.1\| putative 3-oxoacyl-[acyl-carrier protein] reductase [Psychroflexus to...	252.0	[0..48]	[312..4]
gi\|158320488, gi... - gi\|158320488\|ref\|YP_001512995.1\| 3-oxoacyl-(acyl-carrier-protein) reductase [Alkaliphilus oremlandii...	251.0	[0..54]	[314..2]
gi\|20807919 - gi\|20807919\|ref\|NP_623090.1\| Dehydrogenase with different specificities (related to short-chain alco... gi\|20807919, gi\|... - gi\|20807919\|ref\|NP_623090.1\| dehydrogenase [Thermoanaerobacter tengcongensis MB4], gi\|20516487\|gb\|AA...	251.0	[0..58]	[314..6]

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Predicted Domain #1

Region A:
Residues: [1-341]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDGEVLANKS CCGAVVTAFS VIGIVFTILK FTSFASFVYK TFFAKGVKLS VYGAKKGYWA  60
   61 VVTGATDGIG KEYATQLAMS GFNVVLISRT QEKLDALAKE LETVAKVKTR TIAIDYTKTT 120
  121 AETFEKLHQD LVGTPITVLI NNVGQSHYMP TSFAETTVKE MDDIMHINCF GTLHTTKAVL 180
  181 SIMLRERQKN EKGPRCLILT MGSFAGLLPS PYLSTYAGSK AFLSNWSASL GEEVKKQGID 240
  241 VWCFNSYLVV SAMSKVRRPT LTIPTPKKFV RAALSSIGLQ RGGTNPYISQ PYPSHAVMSW 300
  301 SLEQLLGSAK GFVVSQVAAM HLSIRKRALR KEARLQAQNQ A

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	52.522879
Match:	1yxmA
Description:	Crystal structure of peroxisomal trans 2-enoyl CoA reductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity	3.09625241707629	bayes_pls_golite062009
catalytic activity	1.79741889688267	bayes_pls_golite062009
steroid dehydrogenase activity	1.75109362865449	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.65338499044318	bayes_pls_golite062009
retinol dehydrogenase activity	1.62479182657896	bayes_pls_golite062009
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.55012034958204	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.47309297191111	bayes_pls_golite062009
fatty acid synthase activity	1.23679054027553	bayes_pls_golite062009
receptor binding	0.709252240951165	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	0.62461633437589	bayes_pls_golite062009
3-oxoacyl-[acyl-carrier-protein] reductase activity	0.604742541607263	bayes_pls_golite062009
DNA binding	0.601481537720345	bayes_pls_golite062009
binding	0.553666136934364	bayes_pls_golite062009
protein binding	0.507836099271263	bayes_pls_golite062009
nucleic acid binding	0.496304085386733	bayes_pls_golite062009
molecular transducer activity	0.435382281024944	bayes_pls_golite062009
signal transducer activity	0.435382281024944	bayes_pls_golite062009
transcription regulator activity	0.424440926701713	bayes_pls_golite062009
collagen binding	0.33413715668588	bayes_pls_golite062009
3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity	0.300486904096971	bayes_pls_golite062009
retinoid binding	0.29354863903527	bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity	0.233238483713519	bayes_pls_golite062009
receptor activity	0.219998435023684	bayes_pls_golite062009
isoprenoid binding	0.1787079123552	bayes_pls_golite062009
transmembrane receptor activity	0.0180992866169776	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: