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View Structure Prediction Details

Protein: pfs2
Organism: Schizosaccharomyces pombe
Length: 509 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pfs2.

Description E-value Query
Range
Subject
Range
gi|186464325, gi... - gi|23128981|ref|ZP_00110817.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668187...
536.0 [0..1] [508..1178]
gi|75701503, gi|... - gi|75907778|ref|YP_322074.1| ribosome assembly protein 4 (RSA4) [Anabaena variabilis ATCC 29413], gi...
518.0 [0..1] [508..1092]
gi|35214926, gi|... - gi|37523920|ref|NP_927297.1| WD repeat-containing protein [Gloeobacter violaceus PCC 7421], gi|35214...
509.0 [0..1] [509..571]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
502.0 [0..1] [508..870]
gi|115443476, gi... - gi|115443476|ref|XP_001218545.1| hypothetical protein ATEG_09923 [Aspergillus terreus NIH2624], gi|1...
498.0 [0..1] [508..654]

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Predicted Domain #1
Region A:
Residues: [1-81]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERAENARII QKPMTRRTVD YGSGLSKYIV NRHLRSNRYH IHVPRPNPNQ IINLYPPYEY  60
   61 KYNNTSSLCT KYIHTSANKA R

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 69.39794
Match: 2gnqA
Description: No description for 2gnqA was found.

Predicted Domain #2
Region A:
Residues: [82-143]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HVINVVRWTP DGRRLLTGSS TGEFTLWNGL TFNFELINQS HDYAVRCAEW STDGRWLISG  60
   61 DG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.39794
Match: 1k8kC
Description: Arp2/3 complex 41 kDa subunit ARPC1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [144-509]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGMVKYFEPN LNNVKIVQAH EMEVRDVAFS PNDSKFVTAS DDGSLKVWNF HMSTEELKLT  60
   61 GHGWDVKTVD WHPSKGLLAS GSKDNLVKFW DPRTGTCIAT LHGHKNTIMQ ASFQKNFGSN 120
  121 YLATVSRDST CRVFDLRAMK DVRVLRGHEK DVNCVTWHPL YPNLLTTGGS DGSVNHYSLD 180
  181 EPPLLSQQKY HEKHPNVTLS ASSYLLYPTA EIPFAHDLGI WSMQYHPLGH LLCTGSNDKT 240
  241 TRFWSRSRPD DKESTMDRHH LGEEQSEAML SQRKAAIEED DNYEPDENPL TETLANAHNP 300
  301 QFSGVLNLPG LGTMPSFPSP YQHGQPQIPG MLHASLSNSY AEPSTQNSFI PGLTSKSQDG 360
  361 YPQNYR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.39794
Match: 1gg2B
Description: beta1-subunit of the signal-transducing G protein heterotrimer
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
6.67009948605948 bayes_pls_golite062009
RNA binding 3.77273677738815 bayes_pls_golite062009
actin binding 3.31804728298431 bayes_pls_golite062009
snoRNA binding 3.28507672512266 bayes_pls_golite062009
GTPase activity 3.23750443966606 bayes_pls_golite062009
cytoskeletal protein binding 3.1056443224755 bayes_pls_golite062009
tubulin binding 2.76945430061825 bayes_pls_golite062009
microtubule binding 2.72684103222924 bayes_pls_golite062009
dynein binding 2.54821997913979 bayes_pls_golite062009
binding 2.42570478946173 bayes_pls_golite062009
transcription regulator activity 2.3610959773142 bayes_pls_golite062009
nucleic acid binding 2.30918780727915 bayes_pls_golite062009
transcription repressor activity 2.29049708962212 bayes_pls_golite062009
protein binding 2.26925404328312 bayes_pls_golite062009
dynactin binding 1.85146647785657 bayes_pls_golite062009
DNA binding 1.71685536470455 bayes_pls_golite062009
actin filament binding 1.5197243426595 bayes_pls_golite062009
structural molecule activity 1.47097979074281 bayes_pls_golite062009
transcription corepressor activity 1.41752877005447 bayes_pls_golite062009
transporter activity 1.21549336905926 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.21305848427711 bayes_pls_golite062009
receptor activity 1.12819778129653 bayes_pls_golite062009
G-protein-coupled receptor binding 1.11754260203517 bayes_pls_golite062009
transcription factor activity 1.08768505897883 bayes_pls_golite062009
mRNA binding 1.05053985350578 bayes_pls_golite062009
microtubule plus-end binding 1.01166033978052 bayes_pls_golite062009
molecular transducer activity 0.974380908248463 bayes_pls_golite062009
signal transducer activity 0.974380908248463 bayes_pls_golite062009
ligase activity 0.93058496790047 bayes_pls_golite062009
substrate-specific transporter activity 0.734793983890004 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.676924760416604 bayes_pls_golite062009
transcription factor binding 0.489473003915035 bayes_pls_golite062009
dynein intermediate chain binding 0.443846546939402 bayes_pls_golite062009
transcription cofactor activity 0.30761651528651 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.168317261786777 bayes_pls_golite062009
histone binding 0.166694897714113 bayes_pls_golite062009
chromatin binding 0.151977098745772 bayes_pls_golite062009
kinase activity 0.127621956173205 bayes_pls_golite062009
structural constituent of cytoskeleton 0.118975415284669 bayes_pls_golite062009
receptor binding 0.0390635451962911 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00585398682921312 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle