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View Structure Prediction Details

Protein: seh1
Organism: Schizosaccharomyces pombe
Length: 339 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for seh1.

Description E-value Query
Range
Subject
Range
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
290.0 [0..1] [338..1145]
gi|186464325, gi... - gi|23128981|ref|ZP_00110817.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668187...
287.0 [0..1] [337..1243]
gi|75701503, gi|... - gi|75907778|ref|YP_322074.1| ribosome assembly protein 4 (RSA4) [Anabaena variabilis ATCC 29413], gi...
284.0 [0..1] [338..1199]
gi|37523925, gi|... - gi|37523925|ref|NP_927302.1| WD repeat-containing protein [Gloeobacter violaceus PCC 7421], gi|35214...
283.0 [0..3] [337..810]
HETE1_PODAS - Vegetative incompatibility protein HET-E-1 OS=Podospora anserina GN=HET-E1 PE=3 SV=1
270.0 [0..3] [338..914]

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Predicted Domain #1
Region A:
Residues: [1-339]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDISATTIQ TNHQDLVNDV TYDFYGRRMV SCSADQRVKV YDFNDDTETW AITSEWRAGD  60
   61 ASLMRVAWAH PSFGQVLAVC SLDRGVRIYE EQKKNFESKT WVEVAKLMDA RSAVLDISFC 120
  121 PFQHGCKLAA VSADATLRIY EAMEPGNLTY WTLMNEIALM PSPPSRNEQP AFCVNWCPSR 180
  181 WREQYIAVGC MNDAYIYKQN SHGKWKKVAE LPGHTDLIRD ICWAPSMGSS YYLIATACKD 240
  241 GNVRIFKVET LCEEVFQEEE DAGNSMTEDS NFNLNSLKVE LIGEYDNHKC QVWRCRFNVT 300
  301 GTILSSSGDD GCVRLWKASY ANLFKCISVV SLEKKPEKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.0
Match: 1vyhC
Description: PAF-AH Holoenzyme: Lis1/Alfa2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.42570478946173 bayes_pls_golite062009
transcription regulator activity 2.3610959773142 bayes_pls_golite062009
nucleic acid binding 2.30918780727915 bayes_pls_golite062009
protein binding 2.26925404328312 bayes_pls_golite062009
DNA binding 1.71685536470455 bayes_pls_golite062009
GTPase activity 1.66665311782591 bayes_pls_golite062009
snoRNA binding 1.61553185503007 bayes_pls_golite062009
ubiquitin-protein ligase activity 1.59258100795958 bayes_pls_golite062009
transporter activity 1.21549336905926 bayes_pls_golite062009
transcription factor activity 1.08768505897883 bayes_pls_golite062009
protein transporter activity 0.964340340346761 bayes_pls_golite062009
0.88172763425403 bayes_pls_golite062009
substrate-specific transporter activity 0.734793983890004 bayes_pls_golite062009
structural molecule activity 0.721739615005709 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.676924760416604 bayes_pls_golite062009
transcription repressor activity 0.658573452658359 bayes_pls_golite062009
molecular transducer activity 0.577438981735303 bayes_pls_golite062009
signal transducer activity 0.577438981735303 bayes_pls_golite062009
acid-amino acid ligase activity 0.535041400676017 bayes_pls_golite062009
transcription factor binding 0.489473003915035 bayes_pls_golite062009
cytoskeletal protein binding 0.359536347486199 bayes_pls_golite062009
receptor activity 0.322599767074871 bayes_pls_golite062009
transcription cofactor activity 0.30761651528651 bayes_pls_golite062009
transcription corepressor activity 0.182612389752591 bayes_pls_golite062009
hydrolase activity 0.181211933860468 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.168317261786777 bayes_pls_golite062009
chromatin binding 0.151977098745772 bayes_pls_golite062009
kinase activity 0.127621956173205 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.121872424136545 bayes_pls_golite062009
receptor binding 0.0390635451962911 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00585398682921312 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle