YRC Public Data Repository - Protein Structure Prediction

Protein:	rhp55
Organism:	Schizosaccharomyces pombe
Length:	350 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rhp55.

Description	E-value	Query Range	Subject Range
gi\|90309945, gi\|... - gi\|90408944\|ref\|ZP_01217078.1\| putative RecA protein [Psychromonas sp. CNPT3], gi\|90309945\|gb\|EAS380...	209.0	[0..4]	[260..26]
RECA_MANHA - Protein RecA OS=Mannheimia haemolytica GN=recA PE=3 SV=1 gi\|197748450, gi... - gi\|254362313\|ref\|ZP_04978425.1\| recombinase RecA [Mannheimia haemolytica PHL213], gi\|197748450\|ref\|Y...	205.0	[0..4]	[260..39]
RECA_PSYWF - Protein RecA OS=Psychrobacter sp. (strain PRwf-1) GN=recA PE=3 SV=1	205.0	[0..3]	[283..23]
gi\|9654971, gi\|1... - gi\|9654971\|gb\|AAF93711.1\| recA protein [Vibrio cholerae O1 biovar El Tor str. N16961], gi\|15640565\|r... gi\|11356058 - gi\|11356058\|pir\|\|E82310 recA protein VC0543 [imported] - Vibrio cholerae (strain N16961 serogroup O1...	205.0	[0..4]	[264..82]
gi\|71361898 - gi\|71361898\|gb\|AAZ30056.1\| recombinant protein A [Moraxella catarrhalis]	204.0	[0..3]	[296..23]
RECA_PSYCK - Protein RecA OS=Psychrobacter cryohalolentis (strain K5) GN=recA PE=3 SV=1	204.0	[0..3]	[292..23]
RECA_PSYA2 - Protein RecA OS=Psychrobacter arcticus (strain DSM 17307 / 273-4) GN=recA PE=3 SV=1	203.0	[0..3]	[292..23]
gi\|53729046 - gi\|53729046\|ref\|ZP_00134135.2\| COG0468: RecA/RadA recombinase [Actinobacillus pleuropneumoniae serov...	203.0	[0..4]	[260..41]
gi\|66270756 - gi\|66270756\|gb\|AAY43691.1\| RecA/GFP fusion protein [Cloning vector pSJS1472]	203.0	[0..4]	[264..26]
gi\|37680989, gi\|... - gi\|37680989\|ref\|NP_935598.1\| recombinase A [Vibrio vulnificus YJ016], gi\|37199739\|dbj\|BAC95569.1\| Re...	203.0	[0..4]	[264..44]

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Predicted Domain #1

Region A:
Residues: [1-258]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSSQHRLVT QPAIRAYEAF SAPGFGFNSK LLDDAFGGSG LKRGYISEVC GAPGMGKTSL  60
   61 ALQITANALL SGSRVIWVET CQPIPMERLR QLLDNHVPSS QDEEEKCDTD ELLNLLDVVY 120
  121 APNLVNILAF LRNFDQEKHL KEIGLLIIDN LSMPIQLAYP TSPEDYAYLR LRRNTSKKSS 180
  181 LSDSSQKENT LTLNKENEFS SKDDSNFAFH NSSTKTTINR RKKAIGTISS LLSKITSSCY 240
  241 VAIFVTTQMT SKVVSGIG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.39794
Match:	1n03A
Description:	RecA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.4974940028864	bayes_pls_golite062009
nucleoside-triphosphatase activity	2.16381244011837	bayes_pls_golite062009
pyrophosphatase activity	2.13284212711072	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	2.11265775498161	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	2.11046854230259	bayes_pls_golite062009
helicase activity	1.70242731830224	bayes_pls_golite062009
hydrolase activity	1.66122526893602	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	1.56989255954747	bayes_pls_golite062009
ATPase activity	1.53315090215319	bayes_pls_golite062009
structure-specific DNA binding	1.2539059700735	bayes_pls_golite062009
DNA-dependent ATPase activity	1.2155186842031	bayes_pls_golite062009
purine NTP-dependent helicase activity	1.19311444180077	bayes_pls_golite062009
ATP-dependent helicase activity	1.19311444180077	bayes_pls_golite062009
microtubule motor activity	1.170087579765	bayes_pls_golite062009
double-stranded DNA binding	1.117585097627	bayes_pls_golite062009
nucleic acid binding	1.08697924060619	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
DNA helicase activity	0.72881469450553	bayes_pls_golite062009
DNA binding	0.702147676354075	bayes_pls_golite062009
motor activity	0.677658554107	bayes_pls_golite062009
ATP-dependent DNA helicase activity	0.5886142102548	bayes_pls_golite062009
single-stranded DNA binding	0.568457189190858	bayes_pls_golite062009
protein binding	0.378225828131122	bayes_pls_golite062009
RNA helicase activity	0.34746349346164	bayes_pls_golite062009
mismatched DNA binding	0.31144582840038	bayes_pls_golite062009
ATP-dependent RNA helicase activity	0.30832907234141	bayes_pls_golite062009
RNA-dependent ATPase activity	0.29532978396745	bayes_pls_golite062009
transcription regulator activity	0.287777990975748	bayes_pls_golite062009
four-way junction helicase activity	0.26252931460003	bayes_pls_golite062009
exodeoxyribonuclease V activity	0.185603938981231	bayes_pls_golite062009
nucleotide binding	0.114848452385726	bayes_pls_golite062009
purine nucleotide binding	0.10713474095071	bayes_pls_golite062009
purine ribonucleotide binding	0.0916519414118148	bayes_pls_golite062009
ribonucleotide binding	0.0915913646217636	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [259-350]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKLIPLLSTN WLDNLSYRLI LYSRHSTEES KDGQSRPSHQ LLRYAFMAKQ PPAHSAESEL  60
   61 AFQLTSTGIQ DYQSIPTNSS QRRKRSILEC ES

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: