YRC Public Data Repository - Protein Structure Prediction

Protein:	ceg1
Organism:	Schizosaccharomyces pombe
Length:	402 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ceg1.

Description	E-value	Query Range	Subject Range
gi\|49108440, gi\|... - gi\|67900972\|ref\|XP_680742.1\| hypothetical protein AN7473.2 [Aspergillus nidulans FGSC A4], ref\|XP_41...	282.0	[0..15]	[392..409]
gi\|157817358, gi... - gi\|157817358\|ref\|NP_001101393.1\| RNA guanylyltransferase and 5'-phosphatase [Rattus norvegicus], gi\|...	275.0	[0..8]	[394..233]
MCE1_MOUSE - mRNA-capping enzyme OS=Mus musculus GN=Rngtt PE=1 SV=1	275.0	[0..8]	[394..233]
gi\|83767047 - gi\|83767047\|dbj\|BAE57187.1\| unnamed protein product [Aspergillus oryzae] gi\|169769438 - gi\|169769438\|ref\|XP_001819189.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|220692425, gi... - gi\|238501908\|ref\|XP_002382188.1\| mRNA capping enzyme alpha subunit, putative [Aspergillus flavus NRR...	268.0	[0..8]	[390..5]
gi\|46125147, gi\|... - gi\|46125147\|ref\|XP_387127.1\| hypothetical protein FG06951.1 [Gibberella zeae PH-1], gi\|42554155\|gb\|E...	268.0	[0..1]	[373..1]
gi\|114608530 - gi\|114608530\|ref\|XP_518633.2\| PREDICTED: RNA guanylyltransferase and 5'-phosphatase [Pan troglodytes...	266.0	[0..8]	[387..324]
gi\|73973895 - gi\|73973895\|ref\|XP_539035.2\| PREDICTED: similar to mRNA capping enzyme (HCE) (HCAP1) [Canis familiar...	266.0	[0..8]	[387..343]
gi\|86438394, gi\|... - gi\|86438394\|gb\|AAI12846.1\| RNA guanylyltransferase and 5'-phosphatase [Bos taurus], gi\|114052524\|ref...	266.0	[0..8]	[394..233]
gi\|18042848 - gi\|18042848\|gb\|AAH19954.1\| RNA guanylyltransferase and 5'-phosphatase [Homo sapiens]	265.0	[0..8]	[387..233]

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Predicted Domain #1

Region A:
Residues: [1-402]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPSEKDIEE VSVPGVLAPR DDVRVLKTRI AKLLGTSPDT FPGSQPVSFS KKHLQALKEK  60
   61 NYFVCEKSDG IRCLLYMTEH PRYENRPSVY LFDRKMNFYH VEKIFYPVEN DKSGKKYHVD 120
  121 TLLDGELVLD IYPGGKKQLR YLVFDCLACD GIVYMSRLLD KRLGIFAKSI QKPLDEYTKT 180
  181 HMRETAIFPF LTSLKKMELG HGILKLFNEV IPRLRHGNDG LIFTCTETPY VSGTDQSLLK 240
  241 WKPKEMNTID FMLKLEFAQP EEGDIDYSAM PEFQLGVWEG RNMYSFFAFM YVDEKEWEKL 300
  301 KSFNVPLSER IVECYLDDEN RWRFLRFRDD KRDANHISTV KSVLQSIEDG VSKEDLLKEM 360
  361 PIIREAYYNR KKPSVTKRKL DETSNDDAPA IKKVAKESEK EI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	65.0
Match:	1p16A
Description:	mRNA capping enzyme alpha subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
mRNA guanylyltransferase activity	8.90512192081791	bayes_pls_golite062009
RNA guanylyltransferase activity	8.46124967325993	bayes_pls_golite062009
ligase activity, forming phosphoric ester bonds	2.90848936326491	bayes_pls_golite062009
DNA ligase activity	2.88630907730339	bayes_pls_golite062009
nucleic acid binding	2.49304224824605	bayes_pls_golite062009
ligase activity	2.44151794329612	bayes_pls_golite062009
RNA binding	2.41160981373213	bayes_pls_golite062009
DNA binding	2.3408239279957	bayes_pls_golite062009
catalytic activity	2.15370807854636	bayes_pls_golite062009
transcription regulator activity	2.10110937001387	bayes_pls_golite062009
sequence-specific DNA binding	1.9581702424972	bayes_pls_golite062009
binding	1.82998145778732	bayes_pls_golite062009
structure-specific DNA binding	1.81524862921454	bayes_pls_golite062009
guanylyltransferase activity	1.64088197294498	bayes_pls_golite062009
single-stranded DNA binding	1.62996999055328	bayes_pls_golite062009
	1.5765009871268	bayes_pls_golite062009
structural constituent of ribosome	1.51215866188241	bayes_pls_golite062009
protein binding	1.38006517521813	bayes_pls_golite062009
transcription activator activity	1.24141936405635	bayes_pls_golite062009
ribonuclease activity	1.19236946227657	bayes_pls_golite062009
structural molecule activity	1.16496993393687	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	1.15212468568198	bayes_pls_golite062009
transcription factor activity	1.14242112812892	bayes_pls_golite062009
exoribonuclease activity	1.10445667068538	bayes_pls_golite062009
DNA ligase (ATP) activity	1.02324195596817	bayes_pls_golite062009
3'-5'-exoribonuclease activity	0.83268201349295	bayes_pls_golite062009
DNA ligase (NAD+) activity	0.802565778478831	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.583085644017496	bayes_pls_golite062009
nuclease activity	0.57381531077345	bayes_pls_golite062009
translation regulator activity	0.515576958825022	bayes_pls_golite062009
RNA polymerase activity	0.510809870824979	bayes_pls_golite062009
DNA-directed RNA polymerase activity	0.510809870824979	bayes_pls_golite062009
translation factor activity, nucleic acid binding	0.468402630523277	bayes_pls_golite062009
mRNA binding	0.4162128308402	bayes_pls_golite062009
translation initiation factor activity	0.2080607201312	bayes_pls_golite062009
chromatin binding	0.19409870825073	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: