| Protein: | gi|24640536, gi|... |
| Organism: | Drosophila melanogaster |
| Length: | 1161 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24640536, gi|....
| Description | E-value | Query Range |
Subject Range |
|
|
694.0 | [0..1] | [1161..1] |
|
Region A: Residues: [1-409] |
1 11 21 31 41 51
| | | | | |
1 MPSQVSRGLD TTNMLPISEE QQLQQQQQQQ QLEQLHHPQI PEIPIPDLEQ VETQVGDGSL 60
61 WTALYDYDAQ GEDELTLRRG EIVVVLSTDS EVSGDVGWWT GKIGDKVGVF PKDFVTDEDP 120
121 LQLNVSSAIG DIQPHEIEYN ELDIKEVIGS GGFCKVHRGY YDGEEVAIKI AHQTGEDDMQ 180
181 RMRDNVLQEA KLFWALKHEN IAALRGVCLN TKLCLVMEYA RGGSLNRILA GKIPPDVLVN 240
241 WAIQIARGMN YLHNEAPMSI IHRDLKSSNV LIYEAIEGNH LQQKTLKITD FGLAREMYNT 300
301 QRMSAAGTYA WMPPEVISVS TYSKFSDVWS YGVLLWELIT GETPYKGFDP LSVAYGVAVN 360
361 TLTLPIPKTC PETWGALMKS CWQTDPHKRP GFKEILKQLE SIACSKFTL
|
| Detection Method: |  |
| Confidence: | 92.39794 |
| Match: | 2ptkA |
| Description: | CHICKEN SRC TYROSINE KINASE |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein kinase activity | 5.63683237027974 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 5.24105099841813 | bayes_pls_golite062009 |
| kinase activity | 5.02394449930162 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.38615595541751 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.33927583810751 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 3.41480681854114 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 3.40140621607334 | bayes_pls_golite062009 |
| transferase activity | 3.26787750561728 | bayes_pls_golite062009 |
| epidermal growth factor receptor binding | 2.9751846707539 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.59526003830791 | bayes_pls_golite062009 |
| signal transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| molecular transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| receptor activity | 2.39311927684508 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| binding | 2.10874590528357 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| molecular adaptor activity | 1.81145713371725 | bayes_pls_golite062009 |
| non-membrane spanning protein tyrosine kinase activity | 1.66669268613198 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| vinculin binding | 1.63216315345235 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| SH3/SH2 adaptor activity | 1.59474164216385 | bayes_pls_golite062009 |
| growth factor binding | 1.53863828216563 | bayes_pls_golite062009 |
| kinase binding | 1.26086833316556 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 1.25285260301349 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 1.10045286406485 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 1.10045286406485 | bayes_pls_golite062009 |
| protein kinase binding | 1.06030596516506 | bayes_pls_golite062009 |
| protein binding, bridging | 0.777367738889091 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 0.75189004129952 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 0.74324450025139 | bayes_pls_golite062009 |
| transporter activity | 0.710766490066447 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.60324822483033 | bayes_pls_golite062009 |
| activin binding | 0.510364757301021 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.385603245903806 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.371991354471077 | bayes_pls_golite062009 |
| magnesium ion binding | 0.310771535422373 | bayes_pls_golite062009 |
| enzyme binding | 0.268058321307564 | bayes_pls_golite062009 |
| protein complex binding | 0.239339759110451 | bayes_pls_golite062009 |
| insulin receptor activity | 0.188254408239569 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.152203945257581 | bayes_pls_golite062009 |
| MAP kinase activity | 0.0675236791909441 | bayes_pls_golite062009 |
| sevenless binding | 0.0591955406382375 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type I | 0.0506751594607393 | bayes_pls_golite062009 |
| JUN kinase kinase kinase kinase activity | 0.0393215018817107 | bayes_pls_golite062009 |
|
Region A: Residues: [410-553] |
1 11 21 31 41 51
| | | | | |
1 TPQESFHYMQ ECWRKEIAGV LHDLREKEKE LRNKEEQLLR VQNEQREKAN LLKIREQNLR 60
61 ERERVLIERE LVMLQPVPSK RKHKKGKKNK PLQISLPTGF RHTITAVRDK AEQPGSPSFS 120
121 GLRIVALTDG HKGKTWGPST MHQR
|
| Detection Method: | |
| Confidence: | 48.0 |
| Match: | 1koaA |
| Description: | TWITCHIN KINASE FRAGMENT (C.ELEGANS), AUTOREGULATED PROTEIN KINASE AND IMMUNOGLOBULIN DOMAINS |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [554-614] |
1 11 21 31 41 51
| | | | | |
1 ERSLLPSQLS GGQPEWPAQT STHSSFSKSA PNLDKKQQQQ NQQQVASLTP PPGLGILGGS 60
61 G
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [615-734] |
1 11 21 31 41 51
| | | | | |
1 GAGGTPATPL LYPGIPIILT RPNNNNIGNC KAITTTITTT TTTTTNNNNN NNNSISANNN 60
61 NQLNNISTIN SNNNNNQTNL TSQPNTIIVL QNGRNNSNSS TTSQSPAKIY HRARSQEYGL 120
121
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [735-896] |
1 11 21 31 41 51
| | | | | |
1 DHPLAYQPPP LYLVTDDSSE TDTVASPTGC FHFLKSGNSS AASGAVHLHR FGGSLGNSPA 60
61 VGRKKHSLDS SSHHPPANGS NSFALPNQLT LPSEDNNTYD HAFYRDVIKK MSMASSERVN 120
121 SKSSGDLTMY NSSTPLTARD CDDAEEAFEG GRFQRNFSGS QF
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [897-1082] |
1 11 21 31 41 51
| | | | | |
1 PRHCFFTRQE EEGEAEDEDA VAAEVDTADA DADDECQVPA SQMRQNSTTS RKSSVTFQSV 60
61 SFEEPDFVAT PRTTARSDLY TSSASISFAT YRSASPSLSS SSTTASASPS IASTEAVNGY 120
121 HMQENSILNT RRMQDVQPHP DVIKLRAQEQ RQQTKNQKKQ RPKHITKSKS VEAPVEGQHH 180
181 EHDDHN
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1083-1161] |
1 11 21 31 41 51
| | | | | |
1 DPQHQHHSAG SSKIRALFNL FTRSRKKYSK LAEHNMVGGP EFCAIDPYQT DLAMGGSSRS 60
61 LKRKGKKPQT QSCEQLERC
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
