| Protein: | FBpp0309145, Smox-PA |
| Organism: | Drosophila melanogaster |
| Length: | 486 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0309145, Smox-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
558.0 | [0..1] | [486..1] |
|
Region A: Residues: [1-120] |
1 11 21 31 41 51
| | | | | |
1 MLPFTPQVVK RLLALKKGNE DNSVEGKWSE KAVKNLVKKI KKNSQLEELE RAISTQNCQT 60
61 RCVTVPRSKP APAGEHLRKG LPHVIYCRLW RWPDLQSQNE LKPLDHCEYA FHLRKEEICI 120
121
|
| Detection Method: |  |
| Confidence: | 54.30103 |
| Match: | 1mhdA |
| Description: | SMAD MH1 domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [121-240] |
1 11 21 31 41 51
| | | | | |
1 NPYHYKKIEL SILVPKSLPT PPDSIVDYPL DNHTHQIPNN TDYNAAIIRS ASLSPPQYME 60
61 LGGAGPVSVS SSASSTPATA AGGGGGPSSS SSSSSSAASA YQQQQQQLSF GQNMDSQSSV 120
121
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [241-486] |
1 11 21 31 41 51
| | | | | |
1 LSVGSSIPNT GTPPPGYMSE DGDPIDPNDN MNMSRLTPPA DAAPVMYHEP AFWCSISYYE 60
61 LNTRVGETFH ASQPSITVDG FTDPSNSERF CLGLLSNVNR NEVVEQTRRH IGKGVRLYYI 120
121 GGEVFAECLS DSSIFVQSPN CNQRYGWHPA TVCKIPPGCN LKIFNNQEFA ALLSQSVSQG 180
181 FEAVYQLTRM CTIRMSFVKG WGAEYRRQTV TSTPCWIELH LNGPLQWLDR VLTQMGSPRL 240
241 PCSSMS
|
| Detection Method: | |
| Confidence: | 94.39794 |
| Match: | 1khxA |
| Description: | Smad2 MH2 domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| R-SMAD binding | 5.38307893104629 | bayes_pls_golite062009 |
| transforming growth factor beta receptor, cytoplasmic mediator activity | 5.17758651944685 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase signaling protein activity | 4.95270065635384 | bayes_pls_golite062009 |
| co-SMAD binding | 4.57538059815089 | bayes_pls_golite062009 |
| transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity | 4.49077041445033 | bayes_pls_golite062009 |
| SMAD binding | 4.23556933524744 | bayes_pls_golite062009 |
| binding | 3.6561903894619 | bayes_pls_golite062009 |
| transcription regulator activity | 3.49687772656017 | bayes_pls_golite062009 |
| protein binding | 3.44553762357492 | bayes_pls_golite062009 |
| DNA binding | 3.30334070294767 | bayes_pls_golite062009 |
| type I transforming growth factor beta receptor binding | 3.25693690222359 | bayes_pls_golite062009 |
| nucleic acid binding | 3.21526555447097 | bayes_pls_golite062009 |
| transcription activator activity | 2.94935902482394 | bayes_pls_golite062009 |
| receptor serine/threonine kinase binding | 2.94401714632865 | bayes_pls_golite062009 |
| signal transducer activity | 2.90288654612667 | bayes_pls_golite062009 |
| molecular transducer activity | 2.90288654612667 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.88406197124131 | bayes_pls_golite062009 |
| activin binding | 2.85561990563659 | bayes_pls_golite062009 |
| transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity | 2.75979335370845 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.63051531362977 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.61166537801555 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase binding | 2.57320437127906 | bayes_pls_golite062009 |
| transforming growth factor beta receptor binding | 2.57320437127906 | bayes_pls_golite062009 |
| phosphatase activity | 2.46582579847871 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 2.41505949322677 | bayes_pls_golite062009 |
| promoter binding | 2.30493918456602 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 2.1294440466744 | bayes_pls_golite062009 |
| transcription factor activity | 2.08449567315174 | bayes_pls_golite062009 |
| collagen binding | 1.9825610927799 | bayes_pls_golite062009 |
| transcription repressor activity | 1.74929788315626 | bayes_pls_golite062009 |
| chromatin binding | 1.44267609273288 | bayes_pls_golite062009 |
| receptor binding | 1.1261895404991 | bayes_pls_golite062009 |
| transforming growth factor beta receptor, common-partner cytoplasmic mediator activity | 1.02877533969699 | bayes_pls_golite062009 |
| histone binding | 1.01074250987871 | bayes_pls_golite062009 |
| transcription factor binding | 0.95553719139833 | bayes_pls_golite062009 |
| ubiquitin protein ligase binding | 0.85140744915405 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.849282290562727 | bayes_pls_golite062009 |
| kinase activity | 0.818037815854114 | bayes_pls_golite062009 |
| protein kinase activity | 0.658065106914619 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.657115605255247 | bayes_pls_golite062009 |
| I-SMAD binding | 0.605133087848961 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.408522209269307 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 0.372418193032456 | bayes_pls_golite062009 |
| enzyme binding | 0.34998623523914 | bayes_pls_golite062009 |
| protein dimerization activity | 0.33340925100096 | bayes_pls_golite062009 |
| transferase activity | 0.294538857017548 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.242323296067 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.163947452198109 | bayes_pls_golite062009 |
| specific transcriptional repressor activity | 0.15013949452504 | bayes_pls_golite062009 |
| identical protein binding | 0.0513801649373811 | bayes_pls_golite062009 |
| protein homodimerization activity | 0.0339057097360133 | bayes_pls_golite062009 |
