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View Structure Prediction Details

Protein: FBpp0303995, dm-PA
Organism: Drosophila melanogaster
Length: 717 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0303995, dm-PA.

Description E-value Query
Range
Subject
Range
gi|4098987 - gi|4098987|gb|AAD00517.1| dMyc1 [Drosophila melanogaster]
570.0 [0..1] [717..1]

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Predicted Domain #1
Region A:
Residues: [1-191]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALYRSDPYS IMDDQLFSNI SIFDMDNDLY DMDKLLSSST IQSDLEKIED MESVFQDYDL  60
   61 EEDMKPEIRN IDCMWPAMSS CLTSGNGNGI ESGNSAASSY SETGAVSLAM VSGSTNLYSA 120
  121 YQRSQTTDNT QSNQQHVVNS AENMPVIIKK ELADLDYTVC QKRLRLSGGD KKSQIQDEVH 180
  181 LIPPGGSLLR K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [192-324]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNNQDIIRKS GELSGSDSIK YQRPDTPHSL TDEVAASEFR HNVDLRACVM GSNNISLTGN  60
   61 DSDVNYIKQI SRELQNTGKD PLPVRYIPPI NDVLDVLNQH SNSTGGQQQL NQQQLDEQQQ 120
  121 AIDIATGRNT VDS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.522879
Match: 2ii0A
Description: No description for 2ii0A was found.

Predicted Domain #3
Region A:
Residues: [325-508]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPTTGSDSDS DDGEPLNFDL RHHRTSKSGS NASITTNNNN SNNKNNKLKN NSNGMLHMMH  60
   61 ITDHSYTRCN DMVDDGPNLE TPSDSDEEID VVSYTDKKLP TNPSCHLMGA LQFQMAHKIS 120
  121 IDHMKQKPRY NNFNLPYTPA SSSPVKSVAN SRYPSPSSTP YQNCSSASPS YSPLSVDSSN 180
  181 VSSS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [509-587]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSSSSSQSSF TTSSSNKGRK RSSLKDPGLL ISSSSVYLPG VNNKVTHSSM MSKKSRGKKV  60
   61 VGTSSGNTSP ISSGQDVDA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [588-717]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDRNWQRRSG GIATSTSSNS SVHRKDFVLG FDEADTIEKR NQHNDMERQR RIGLKNLFEA  60
   61 LKKQIPTIRD KERAPKVNIL REAAKLCIQL TQEEKELSMQ RQLLSLQLKQ RQDTLASYQM 120
  121 ELNESRSVSG 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.154902
Match: 1nkpA
Description: Myc prot-oncogene protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.38658950816179 bayes_pls_golite062009
DNA binding 5.18654839258297 bayes_pls_golite062009
nucleic acid binding 5.05768805749761 bayes_pls_golite062009
transcription factor activity 4.78039531631248 bayes_pls_golite062009
transcription activator activity 3.87875547821718 bayes_pls_golite062009
binding 3.81829206350975 bayes_pls_golite062009
sequence-specific DNA binding 3.42035985454056 bayes_pls_golite062009
protein binding 2.64975291677725 bayes_pls_golite062009
transcription factor binding 2.61163564741984 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.48787404513864 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 2.44519817693888 bayes_pls_golite062009
transcription cofactor activity 1.52770895937238 bayes_pls_golite062009
structure-specific DNA binding 1.07771706364343 bayes_pls_golite062009
transcription repressor activity 0.955588849035129 bayes_pls_golite062009
promoter binding 0.94414084000081 bayes_pls_golite062009
double-stranded DNA binding 0.93846047598021 bayes_pls_golite062009
transcription corepressor activity 0.801830750183111 bayes_pls_golite062009
protein heterodimerization activity 0.53175615551166 bayes_pls_golite062009
transcription coactivator activity 0.3513586903977 bayes_pls_golite062009
protein dimerization activity 0.20674648626116 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle