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View Structure Prediction Details

Protein: FBpp0303995, dm-PA
Organism: Drosophila melanogaster
Length: 717 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0303995, dm-PA.

Description E-value Query
Range
Subject
Range
gi|4098987 - gi|4098987|gb|AAD00517.1| dMyc1 [Drosophila melanogaster]
570.0 [0..1] [717..1]

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Predicted Domain #1
Region A:
Residues: [1-191]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALYRSDPYS IMDDQLFSNI SIFDMDNDLY DMDKLLSSST IQSDLEKIED MESVFQDYDL  60
   61 EEDMKPEIRN IDCMWPAMSS CLTSGNGNGI ESGNSAASSY SETGAVSLAM VSGSTNLYSA 120
  121 YQRSQTTDNT QSNQQHVVNS AENMPVIIKK ELADLDYTVC QKRLRLSGGD KKSQIQDEVH 180
  181 LIPPGGSLLR K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [192-324]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNNQDIIRKS GELSGSDSIK YQRPDTPHSL TDEVAASEFR HNVDLRACVM GSNNISLTGN  60
   61 DSDVNYIKQI SRELQNTGKD PLPVRYIPPI NDVLDVLNQH SNSTGGQQQL NQQQLDEQQQ 120
  121 AIDIATGRNT VDS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.522879
Match: 2ii0A
Description: No description for 2ii0A was found.

Predicted Domain #3
Region A:
Residues: [325-508]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPTTGSDSDS DDGEPLNFDL RHHRTSKSGS NASITTNNNN SNNKNNKLKN NSNGMLHMMH  60
   61 ITDHSYTRCN DMVDDGPNLE TPSDSDEEID VVSYTDKKLP TNPSCHLMGA LQFQMAHKIS 120
  121 IDHMKQKPRY NNFNLPYTPA SSSPVKSVAN SRYPSPSSTP YQNCSSASPS YSPLSVDSSN 180
  181 VSSS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [509-587]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSSSSSQSSF TTSSSNKGRK RSSLKDPGLL ISSSSVYLPG VNNKVTHSSM MSKKSRGKKV  60
   61 VGTSSGNTSP ISSGQDVDA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [588-717]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDRNWQRRSG GIATSTSSNS SVHRKDFVLG FDEADTIEKR NQHNDMERQR RIGLKNLFEA  60
   61 LKKQIPTIRD KERAPKVNIL REAAKLCIQL TQEEKELSMQ RQLLSLQLKQ RQDTLASYQM 120
  121 ELNESRSVSG 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.154902
Match: 1nkpA
Description: Myc prot-oncogene protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.38658950816179 bayes_pls_golite062009
DNA binding 5.18654839258297 bayes_pls_golite062009
nucleic acid binding 5.05768805749761 bayes_pls_golite062009
transcription factor activity 4.78039531631248 bayes_pls_golite062009
transcription activator activity 3.87875547821718 bayes_pls_golite062009
binding 3.81829206350975 bayes_pls_golite062009
sequence-specific DNA binding 3.42035985454056 bayes_pls_golite062009
protein binding 2.64975291677725 bayes_pls_golite062009
transcription factor binding 2.61163564741984 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.48787404513864 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 2.44519817693888 bayes_pls_golite062009
transcription cofactor activity 1.52770895937238 bayes_pls_golite062009
structure-specific DNA binding 1.07771706364343 bayes_pls_golite062009
transcription repressor activity 0.955588849035129 bayes_pls_golite062009
promoter binding 0.94414084000081 bayes_pls_golite062009
double-stranded DNA binding 0.93846047598021 bayes_pls_golite062009
transcription corepressor activity 0.801830750183111 bayes_pls_golite062009
protein heterodimerization activity 0.53175615551166 bayes_pls_golite062009
transcription coactivator activity 0.3513586903977 bayes_pls_golite062009
protein dimerization activity 0.20674648626116 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle