| Protein: | Fur1-PA |
| Organism: | Drosophila melanogaster |
| Length: | 1101 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
|
Region A: Residues: [1-169] |
1 11 21 31 41 51
| | | | | |
1 MKNDVVRWSR QPTSNTTNSS SSSRSDSNST HKHRSKSNKL NARQLGSNAA RSCQQRSSVA 60
61 TTLEDEQQTI IECDIGNFNF DCNLFKTSFL TQHKQKRSGK SSSKSKSNRS RPLAKTKAVF 120
121 LLALQFSAVV FLCNINVGFV AGSVATAASS AGGSSPAAPS SAPSSPPTV
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [170-332] |
1 11 21 31 41 51
| | | | | |
1 AVPPPPPPSS ALKVDPNGQS PVLPPYVLDY ETGGKAKLTP NNGKFGQSGS SGSNNNHIVG 60
61 HYTHTWAVHI PNGDNGMADA VAKDHGFVNL GKIFDDHYHF AHHKVSKRSL SPATHHQTRL 120
121 DDDDRVHWAK QQRAKSRSKR DFIRMRPSRT SSRAMSMVDA MSF
|
| Detection Method: | |
| Confidence: | 13.522879 |
| Match: | 1t1eA |
| Description: | High Resolution Crystal Structure of the Intact Pro-Kumamolisin, a Sedolisin Type Proteinase (previously called Kumamolysin or KSCP) |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [333-787] |
1 11 21 31 41 51
| | | | | |
1 NDSKWPQMWY LNRGGGLDMN VIPAWKMGIT GKGVVVTILD DGLESDHPDI QDNYDPKASY 60
61 DVNSHDDDPM PHYDMTDSNR HGTRCAGEVA ATANNSFCAV GIAYGASVGG VRMLDGDVTD 120
121 AVEARSLSLN PQHIDIYSAS WGPDDDGKTV DGPGELASRA FIEGTTKGRG GKGSIFIWAS 180
181 GNGGREQDNC NCDGYTNSIW TLSISSATEE GHVPWYSEKC SSTLATTYSS GGQGEKQVVT 240
241 TDLHHSCTVS HTGTSASAPL AAGIAALVLQ SNQNLTWRDL QHIVVRTAKP ANLKDPSWSR 300
301 NGVGRRVSHS FGYGLMDAAE MVRVARNWKA VPEQQRCEIN APHVDKVIPP RTHITLQLTV 360
361 NHCRSVNYLE HVQAKITLTS QRRGDIQLFL RSPANTSVTL LTPRIHDNSR SGFNQWPFMS 420
421 VHTWGESPQG NWQLEIHNEG RYMAQITQWD MIFYG
|
| Detection Method: | |
| Confidence: | 93.69897 |
| Match: | 1p8jA |
| Description: | Furin, C-terminal domain; Furin, N-terminal domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| nerve growth factor binding | 5.17216805931457 | bayes_pls_golite062009 |
| peptidase activity | 4.77677490610016 | bayes_pls_golite062009 |
| neurotrophin binding | 4.47215080222714 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 4.40501322467328 | bayes_pls_golite062009 |
| serine hydrolase activity | 4.30899317351154 | bayes_pls_golite062009 |
| serine-type peptidase activity | 4.29545891350519 | bayes_pls_golite062009 |
| endopeptidase activity | 3.83336601331518 | bayes_pls_golite062009 |
| serine-type endopeptidase activity | 3.71508033196614 | bayes_pls_golite062009 |
| hydrolase activity | 2.1123944590511 | bayes_pls_golite062009 |
| eukaryotic cell surface binding | 1.50287724152407 | bayes_pls_golite062009 |
| binding | 1.08901362883653 | bayes_pls_golite062009 |
| catalytic activity | 0.597535457699629 | bayes_pls_golite062009 |
| exopeptidase activity | 0.42083764849682 | bayes_pls_golite062009 |
| protein binding | 0.380935140681308 | bayes_pls_golite062009 |
| receptor binding | 0.222369968782666 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 0.22219445619715 | bayes_pls_golite062009 |
|
Region A: Residues: [788-1101] |
1 11 21 31 41 51
| | | | | |
1 TETPAQPDDV ANPSQSNQFN LYGNDMAHND VEYDSTGQWR NMQQVGEVGM TRDHSNTAAC 60
61 LKWSDRKCLE CNDSAYMFED QCYDVCPVHT YPLDKFQAEE DEQDDEVTRG PVNPYSSSPM 120
121 DHSLLMSNSL DDKQDPLQAE DRRRRSSLTQ LVEVPSRVCA ACDRSCLECY GALASQCSTC 180
181 SPGSQLRKIL NETFCYAYVV RSTGMASVVD ISKMDDRDTQ QYMTGTTVLL LVSVIFTLMG 240
241 VAVAGGIVYH RRAMARSNEL YSRVSLVPGD ESDSDEDELF TAHFPARKSG VNIYRDEAPS 300
301 EKIFEEDEIS HLVP
|
| Detection Method: | |
| Confidence: | 11.30103 |
| Match: | 1n7dA |
| Description: | Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| receptor binding | 3.29563208013266 | bayes_pls_golite062009 |
| growth factor activity | 2.98754787930869 | bayes_pls_golite062009 |
| ErbB-2 class receptor binding | 2.47588813698806 | bayes_pls_golite062009 |
| binding | 2.35148208532935 | bayes_pls_golite062009 |
| ErbB-3 class receptor binding | 1.91029895687059 | bayes_pls_golite062009 |
| protein binding | 1.87564165872234 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 1.69932456942774 | bayes_pls_golite062009 |
| heparin binding | 1.31822233987881 | bayes_pls_golite062009 |
| transcription regulator activity | 1.02533871020185 | bayes_pls_golite062009 |
| pattern binding | 0.889457267222739 | bayes_pls_golite062009 |
| extracellular matrix structural constituent | 0.87690248187077 | bayes_pls_golite062009 |
| transcription factor binding | 0.84948501276694 | bayes_pls_golite062009 |
| polysaccharide binding | 0.815272766842889 | bayes_pls_golite062009 |
| epidermal growth factor receptor binding | 0.78842039074146 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.77044611170692 | bayes_pls_golite062009 |
| signal transducer activity | 0.600269003770368 | bayes_pls_golite062009 |
| molecular transducer activity | 0.600269003770368 | bayes_pls_golite062009 |
| carbohydrate binding | 0.0269430386148981 | bayes_pls_golite062009 |
