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View Structure Prediction Details

Protein: CG5715-PA
Organism: Drosophila melanogaster
Length: 295 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG5715-PA.

Description E-value Query
Range
Subject
Range
gi|108383506 - gi|108383506|gb|ABF85735.1| IP10045p [Drosophila melanogaster]
306.0 [0..1] [295..17]
gi|125776031, gi... - gi|54638886|gb|EAL28288.1| GA19079-PA [Drosophila pseudoobscura], gi|125776031|ref|XP_001359144.1| G...
302.0 [0..4] [295..778]
gi|91084579 - gi|91084579|ref|XP_973910.1| PREDICTED: similar to metalloproteinase, putative [Tribolium castaneum]
279.0 [0..12] [294..4]
gi|149016849, gi... - gi|157823867|ref|NP_001099551.1| tolloid-like 1 [Rattus norvegicus], gi|149016849|gb|EDL75988.1| rCG...
277.0 [0..5] [294..4]
TLL1_MOUSE - Tolloid-like protein 1 OS=Mus musculus GN=Tll1 PE=1 SV=1
276.0 [0..5] [294..4]
TLL1_CHICK - Tolloid-like protein 1 OS=Gallus gallus GN=TLL1 PE=2 SV=1
274.0 [0..14] [294..22]
TLL1 - tolloid-like 1
272.0 [0..13] [294..25]

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Predicted Domain #1
Region A:
Residues: [1-232]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKSQNNTGS LLLLIILGIS LGDSMPLEDM DSQEMIDLTD LGDTLFGNPD VETTGALVEA  60
   61 LGVESPLNPE ELGTYHEGDI LIPLSYRDAR FNGTRNGILA LSSRWPGGVV PYEIKGPFTS 120
  121 QELGNINHAF KEYHTKTCVR FKPRTTEKDY ISIGSGKSGC WSSIGRLGGR QEVNLQSPNC 180
  181 LRTYGTPIHE LMHALGFFHE QNRHERDSYV RVMKDNIKPE MMVNFEKSSS RT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.39794
Match: 1slmA
Description: CRYSTAL STRUCTURE OF FIBROBLAST STROMELYSIN-1: THE C-TRUNCATED HUMAN PROENZYME
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 4.1917763812737 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 3.85190688399485 bayes_pls_golite062009
metallopeptidase activity 3.22757426039234 bayes_pls_golite062009
endopeptidase activity 2.98133341931091 bayes_pls_golite062009
hydrolase activity 2.78513171530601 bayes_pls_golite062009
metalloendopeptidase activity 2.54952091441017 bayes_pls_golite062009
transporter activity 1.28982382930122 bayes_pls_golite062009
binding 1.19918194301835 bayes_pls_golite062009
transmembrane transporter activity 1.0688261398267 bayes_pls_golite062009
catalytic activity 0.891187593353827 bayes_pls_golite062009
substrate-specific transporter activity 0.798767221679673 bayes_pls_golite062009
protein binding 0.553658909577001 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.543737159152136 bayes_pls_golite062009
exopeptidase activity 0.492456025063956 bayes_pls_golite062009
receptor activity 0.332822250208465 bayes_pls_golite062009
ion transmembrane transporter activity 0.241890854867053 bayes_pls_golite062009
transmembrane receptor activity 0.136560284009247 bayes_pls_golite062009
integrin binding 0.0945964646680701 bayes_pls_golite062009
aminopeptidase activity 0.00533877867882504 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [233-295]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QYGFGVEYDY GSVMHYSPTS FTRNGQPTLK ALRATSDASQ MGQRKGFSAG DVRKINAMYK  60
   61 CKV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.39794
Match: 1astA
Description: STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle