| Protein: | gi|74868822, gi|... |
| Organism: | Drosophila melanogaster |
| Length: | 1131 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|74868822, gi|....
| Description | E-value | Query Range |
Subject Range |
|
|
839.0 | [0..133] | [1131..20] |
|
Region A: Residues: [1-152] |
1 11 21 31 41 51
| | | | | |
1 MHGPVSRSSS SSNMTDVSSP AGGAASPVEM STTSSSSAAT TSASSSKPLT NGANKTAIST 60
61 AAGGVTPGAV PGPGSGAIPA SSSSGNQVKL EHHHRQSNNN RPAVTNRSSE TKLMTPTGSS 120
121 SSPSQSPSQT QASIQTQTSQ QDRLAKASTT AS
|
| Detection Method: |  |
| Confidence: | 3.221849 |
| Match: | 1y0fA |
| Description: | No description for 1y0fA was found. |
|
Region A: Residues: [153-233] |
1 11 21 31 41 51
| | | | | |
1 QQDVDEVARL FEEKPEAFEK WLTERAPPEA LSRLQEFIEN RKPHKRPSVT SDLFQQWMAA 60
61 SPTVQQKSPR SLSNSSASSL P
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [234-652] |
1 11 21 31 41 51
| | | | | |
1 ECRRHLMDLD EGELFMELIR DVANELDIDV LCHKILVNVG LLTHADRGSL FLAKGTPTNK 60
61 YLVAKLFDVT QKTALKDAVT RASAEEIIIP FGIGIAGMVA QTKQMINIKE AYKDARFNCE 120
121 IDLKTGYKTN AILCMPICNY EGDIIGVAQI INKTNGCMEF DEHDVEIFRR YLTFCGIGIQ 180
181 NAQLFEMSVQ EYRRNQILLN LARSIFEEQN NLECLVTKIM TEARELLKCE RCSVFLVDLD 240
241 CCEASHLEKI IEKPNQPATR AIKSADSFEE KKMRNRFTVL FELGGEYQAA NVSRPSVSEL 300
301 SSSTLAQIAQ FVATTGQTVN ICDVIEWVRD HNQIRAEDEI DSTQAILCMP IMNAQKKVIG 360
361 VAQLINKANG VPFTDSDASI FEAFAIFCGL GIHNTQMYEN ACKLMAKQKV ALECLSYHA
|
| Detection Method: | |
| Confidence: | 51.221849 |
| Match: | 1mc0A |
| Description: | 3',5'-cyclic nucleotide phosphodiesterase 2A, GAF A and GAF B domains |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| photoreceptor activity | 3.2629375889808 | bayes_pls_golite062009 |
| binding | 2.02315964268807 | bayes_pls_golite062009 |
| 3',5'-cyclic-GMP phosphodiesterase activity | 1.71909707595169 | bayes_pls_golite062009 |
| signal transducer activity | 1.62289915305968 | bayes_pls_golite062009 |
| molecular transducer activity | 1.62289915305968 | bayes_pls_golite062009 |
| 3',5'-cyclic-nucleotide phosphodiesterase activity | 1.56682870530548 | bayes_pls_golite062009 |
| transcription regulator activity | 1.54732950287569 | bayes_pls_golite062009 |
| DNA binding | 1.4095382462656 | bayes_pls_golite062009 |
| nucleic acid binding | 1.38037327227791 | bayes_pls_golite062009 |
| transcription factor activity | 1.10354038063371 | bayes_pls_golite062009 |
| phosphoric diester hydrolase activity | 0.974415378465889 | bayes_pls_golite062009 |
| cyclic-nucleotide phosphodiesterase activity | 0.954654206961074 | bayes_pls_golite062009 |
| receptor activity | 0.875023508303061 | bayes_pls_golite062009 |
| protein binding | 0.321233885659081 | bayes_pls_golite062009 |
|
Region A: Residues: [653-997] |
1 11 21 31 41 51
| | | | | |
1 TASQDQTEKL TQDVIAEAES YNLYSFTFTD FELVDDDTCR AVLRMFMQCN LVSQFQIPYD 60
61 VLCRWVLSVR KNYRPVKYHN WRHALNVAQT MFAMLKTGKM ERFMTDLEIL GLLVACLCHD 120
121 LDHRGTNNAF QTKTESPLAI LYTTSTMEHH HFDQCVMILN SEGNNIFQAL SPEDYRSVMK 180
181 TVESAILSTD LAMYFKKRNA FLELVENGEF DWQGEEKKDL LCGMMMTACD VSAIAKPWEV 240
241 QHKVAKLVAD EFFDQGDLEK LQLNTQPVAM MDRERKDELP KMQVGFIDVI CLPLYRVLCD 300
301 TFPWITPLYE GTLENRRNWQ DLAEKVEMGL TWIDHDTIDK PVEEF
|
| Detection Method: | |
| Confidence: | 102.0 |
| Match: | 1xozA |
| Description: | Catalytic Domain Of Human Phosphodiesterase 5A In Complex With Tadalafil |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| 3',5'-cyclic-GMP phosphodiesterase activity | 4.32481199053516 | bayes_pls_golite062009 |
| 3',5'-cyclic-nucleotide phosphodiesterase activity | 4.15125151181381 | bayes_pls_golite062009 |
| cyclic-nucleotide phosphodiesterase activity | 3.66153187976312 | bayes_pls_golite062009 |
| phosphoric diester hydrolase activity | 3.65984874547256 | bayes_pls_golite062009 |
| 3',5'-cyclic-AMP phosphodiesterase activity | 2.18711955312275 | bayes_pls_golite062009 |
| hydrolase activity | 1.36457789411074 | bayes_pls_golite062009 |
| catalytic activity | 1.07048165010262 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 0.98531713516841 | bayes_pls_golite062009 |
| binding | 0.783822826539632 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 0.511207383357891 | bayes_pls_golite062009 |
| protein binding | 0.162314119157812 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.0142153207240233 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.00598267731749835 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.00281137231762851 | bayes_pls_golite062009 |
|
Region A: Residues: [998-1131] |
1 11 21 31 41 51
| | | | | |
1 AACADEEIKD IEFTVTTLNC NQQSQHGSED SHTPEHQRSG SRLSMKKTGA LGKAVRSKLS 60
61 KTLYNSMDGS KPKTSLKLLE SHVSEDMDDK SPTSPSQPQA SGSMGRMSAS SSTSSAGGQM 120
121 VDKSKKRSKL CALL
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
