| Protein: | Sbf-PB |
| Organism: | Drosophila melanogaster |
| Length: | 1973 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Sbf-PB.
| Description | E-value | Query Range |
Subject Range |
|
|
1875.0 | [0..1] | [1973..1] |
|
Region A: Residues: [1-96] |
1 11 21 31 41 51
| | | | | |
1 MSRLADYFVI VGYDSDKEKT ASNVGGQPTC GKIVQRFPEK DWPDTPFIEG IEWFCQPLGW 60
61 SLSYEKQEPK FFVSVLTDID ANKHYCACLS FHETVA
|
| Detection Method: |  |
| Confidence: | 26.619789 |
| Match: | PF03456.9 |
| Description: | No description for PF03456.9 was found. |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [97-371] |
1 11 21 31 41 51
| | | | | |
1 ITQTRSVDDE DETIGSSRLL GATPSSMDGI TTTSTPASIT HHSVMYAPKC LVLISRLDCA 60
61 ETFKNCLGTI YTVYIENLAY GLETLIGNIL GCIQVPPAGG PQVRFSIGAG DKQSLQPPQS 120
121 SSLPTTGSGV HFLFKQLGIK NVLILLCSVM TENKILFLSK CYWHLTDSCR ALVALMYPFR 180
181 YTHVYIPILP APLTEVLSTP TPFIMGIHSS LQTEITDLLD VIVVDLDGGL VTIPESLTPP 240
241 VPILPSPLWE QTQDLLSMIL FPNLAQADLA FPTLE
|
| Detection Method: | |
| Confidence: | 62.136677 |
| Match: | PF02141.12 |
| Description: | No description for PF02141.12 was found. |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [372-458] |
1 11 21 31 41 51
| | | | | |
1 RPSAIAKTDA QIDKELRAIF MRLFAQLLQG YRSCLTIIRI HPKPVITFHK AGFLGARDLI 60
61 ESEFLFRVLD SMFFTTFVNE RGPPWRS
|
| Detection Method: | |
| Confidence: | 28.920819 |
| Match: | PF03455.10 |
| Description: | No description for PF03455.10 was found. |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [459-577] |
1 11 21 31 41 51
| | | | | |
1 SDAWDELYSS MNELLKSEAQ NRNLILTHIQ ELGRVLYENE GTLAHISYAQ KVLRPPEGAF 60
61 QRIHQPAFPR ISSEKVELII QEGIRKNGVP QRFHVTRNQH RIIPMGPRLP EALDVRPNV
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [578-672] |
1 11 21 31 41 51
| | | | | |
1 QNSARRLEVL RICVSYIFEN RITDARKLLP AVMRTLMHRD ARLILCREFF GYVHGNKAVL 60
61 DHQQFELVVR FMNKALQKSS GIDEYTVAAA LLPMS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [673-806] |
1 11 21 31 41 51
| | | | | |
1 TIFCRKLSTG VVQFAYTEIQ DHAIWKNLQF WESTFFQDVQ GQIKALYLLH RRQNEHQKEA 60
61 NCVLDEVPLE EPTALEITAE QLRKSPNIEE EKKAELAKSE ESTLYSQAIH FANRMVSLLI 120
121 PLDVNVDAAS KPKP
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [807-905] |
1 11 21 31 41 51
| | | | | |
1 AFRLEENQSV SNSIMGSHSL SEHSDEGFEE NNALEIGVTV GKTISRFIDC VCTEGGVTSE 60
61 HIRNLHDMVP GVVHMHIESL EPVYLEAKRH PHVQKPKIQ
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [906-1002] |
1 11 21 31 41 51
| | | | | |
1 TPCLLPGEDL VTDHLRCFLM PDGREDETQC LIPAEGALFL TNYRVIFKGS PCDPLFCEQV 60
61 IVRTFPIASL LKEKKISVLY LAHLDQTLTE GLQLRSS
|
| Detection Method: | |
| Confidence: | 19.086186 |
| Match: | PF02893.11 |
| Description: | No description for PF02893.11 was found. |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1003-1650] |
1 11 21 31 41 51
| | | | | |
1 SFQLIKVAFD PEVTPEQIES FRKILSKARH PFDEFEYFAF QSYGTMLQGV APLKTKEKYS 60
61 TLKGFAKKTL LRGAKKAGFK QKQQTKRKLV SDYDYGSADA QETQSIDDEL EDGDEFETQN 120
121 NAMPRLLTTK DVERMRERSY VQDWKRLGFD AESQRGFRIS NANTSYATCR SYPAIIVAPV 180
181 QCSDAAIMHL GRCFKGQRIP LPTWRHANGA LLIRGGQPNS KSVIGMLKNT TGSTTNAHHD 240
241 VTHYPEQDKY FLALINTMPK LTPLALNQYS GMNLSMSSLM GHSSSDDRQP LTPELSRKHK 300
301 NNLDISDGNK SSQGGKGGTM KGNPKNSLAH PFRKMRLYAL GEKSQAKSNM NVDFCADFIP 360
361 VDYPDIRQSR PAFKKLIRAC MPSHNTNEAD GQSFAKMVEQ SDWLQQISSL MQLSGAVVDL 420
421 IDLQESSVML SLEDGSDVTA QLSSIAQLCL DPYYRSLDGF RVLVEKEWLA FGHRFAHRSN 480
481 LKPSHANTNI AFAPTFLQFL DVVHQLQRQF PMAFEFNDFY LRFLAYHSVS CRFRTFLFDC 540
541 ELERSDSGIA AMEDKRGSLN AKHMFGAGGM ATNGSDDECS VYPLDIRSQR APAPLNRIGH 600
601 SIFDYIERQH NKTPIFYNFL YSGDKSVTLR PQNNVAALDL WCYYTNEE
|
| Detection Method: | |
| Confidence: | 142.0 |
| Match: | 1lw3A |
| Description: | Crystal Structure of Myotubularin-related protein 2 complexed with phosphate |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphoprotein phosphatase activity | 7.30669036331612 | bayes_pls_golite062009 |
| phosphatase activity | 6.53298300144214 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 6.34103372884365 | bayes_pls_golite062009 |
| protein tyrosine phosphatase activity | 5.71552511193227 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 5.10169989192986 | bayes_pls_golite062009 |
| hydrolase activity | 4.27459885320933 | bayes_pls_golite062009 |
| transmembrane receptor protein phosphatase activity | 4.08406741536367 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine phosphatase activity | 4.08406741536367 | bayes_pls_golite062009 |
| protein tyrosine/serine/threonine phosphatase activity | 2.7244435750389 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.46145625794727 | bayes_pls_golite062009 |
| receptor activity | 2.27569467096563 | bayes_pls_golite062009 |
| molecular transducer activity | 2.09373043968997 | bayes_pls_golite062009 |
| signal transducer activity | 2.09373043968997 | bayes_pls_golite062009 |
| protein serine/threonine phosphatase activity | 1.8743338569912 | bayes_pls_golite062009 |
| binding | 1.42026750513729 | bayes_pls_golite062009 |
| protein binding | 1.07441758584517 | bayes_pls_golite062009 |
| catalytic activity | 1.06283028154109 | bayes_pls_golite062009 |
| inositol or phosphatidylinositol phosphatase activity | 0.797185121839876 | bayes_pls_golite062009 |
| lipid phosphatase activity | 0.734449638967758 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 0.60269333716049 | bayes_pls_golite062009 |
| non-membrane spanning protein tyrosine phosphatase activity | 0.594382447716896 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.440408293428823 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 0.368252171155074 | bayes_pls_golite062009 |
| potassium channel activity | 0.33927808168843 | bayes_pls_golite062009 |
| channel activity | 0.29024318255551 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 0.29024318255551 | bayes_pls_golite062009 |
| substrate-specific channel activity | 0.274625894373147 | bayes_pls_golite062009 |
| gated channel activity | 0.217548650508289 | bayes_pls_golite062009 |
| ion channel activity | 0.207688369683596 | bayes_pls_golite062009 |
| cation channel activity | 0.125967756551725 | bayes_pls_golite062009 |
|
Region A: Residues: [1651-1852] |
1 11 21 31 41 51
| | | | | |
1 LAQGAPYDLE VTTVDDEIDL SETKGKRMVI TAGYDNMEKC NPSAYVCLLS EVKQAETERG 60
61 HLPQKWLQVW NSLEVPQLEP VARNTSLGNI FVQTHQHKRS TLEIIMKGRL AGYQDKYFHP 120
121 HRFEKHPYTT PTNCNHCTKL LWGPVGYRCM DCGNSYHEKC TEHSMKNCTK YKAIDGAVGP 180
181 PNVNMSQGDT ASIASSAATT AR
|
| Detection Method: | |
| Confidence: | 13.221849 |
| Match: | 1xa6A |
| Description: | Crystal Structure of the Human Beta2-Chimaerin |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphoprotein phosphatase activity | 2.32814368667748 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 2.27891521507605 | bayes_pls_golite062009 |
| binding | 2.15139804299723 | bayes_pls_golite062009 |
| hydrolase activity | 1.91104671558756 | bayes_pls_golite062009 |
| phosphatase activity | 1.89157568938258 | bayes_pls_golite062009 |
| molecular adaptor activity | 1.69539294439803 | bayes_pls_golite062009 |
| signal transducer activity | 1.5242100351394 | bayes_pls_golite062009 |
| molecular transducer activity | 1.5242100351394 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 1.49104777828784 | bayes_pls_golite062009 |
| SH3/SH2 adaptor activity | 1.48471514043683 | bayes_pls_golite062009 |
| protein binding | 1.29100556128076 | bayes_pls_golite062009 |
| protein binding, bridging | 0.702565329205701 | bayes_pls_golite062009 |
| protein tyrosine phosphatase activity | 0.657349872289543 | bayes_pls_golite062009 |
| receptor binding | 0.58367088800456 | bayes_pls_golite062009 |
| GTPase regulator activity | 0.507221182248837 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 0.482573970055889 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.473228380405599 | bayes_pls_golite062009 |
| kinase activity | 0.401449013594256 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.27531119327217 | bayes_pls_golite062009 |
| protein kinase activity | 0.266851843850147 | bayes_pls_golite062009 |
| catalytic activity | 0.194464246602439 | bayes_pls_golite062009 |
| lipid binding | 0.12073899779791 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.0539426578243308 | bayes_pls_golite062009 |
|
Region A: Residues: [1853-1973] |
1 11 21 31 41 51
| | | | | |
1 TSSHHFYNQF SSNVAENRTH EGHLYKRGAL LKGWKQRWFV LDSIKHQLRY YDTSEDTAPK 60
61 GIIELAEVQS VTAAQPAQIG AKGVDEKGFF DLKTSKRIYN FYAINANLAQ EWIEKLQACL 120
121 Q
|
| Detection Method: | |
| Confidence: | 20.0 |
| Match: | 1v5uA |
| Description: | Solution Structure of the C-terminal Pleckstrin Homology Domain of Sbf1 from Mouse |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.65091781683225 | bayes_pls_golite062009 |
| phosphoprotein phosphatase activity | 2.51186557035049 | bayes_pls_golite062009 |
| protein binding | 2.12168271674167 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 1.9018280968413 | bayes_pls_golite062009 |
| phosphatase activity | 1.90034030060323 | bayes_pls_golite062009 |
| molecular transducer activity | 1.82233415659529 | bayes_pls_golite062009 |
| signal transducer activity | 1.82233415659529 | bayes_pls_golite062009 |
| hydrolase activity | 1.72604953071036 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 1.23074471235333 | bayes_pls_golite062009 |
| receptor activity | 0.819319903902943 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.696394500650961 | bayes_pls_golite062009 |
| protein domain specific binding | 0.51731521446502 | bayes_pls_golite062009 |
| protein tyrosine phosphatase activity | 0.47102669930753 | bayes_pls_golite062009 |
| lipid binding | 0.12933186945671 | bayes_pls_golite062009 |
| receptor signaling protein activity | 0.0787973205518102 | bayes_pls_golite062009 |
| receptor binding | 0.0638301437766597 | bayes_pls_golite062009 |
| phospholipid binding | 0.0143594745448499 | bayes_pls_golite062009 |
