| Protein: | Sbf-PA |
| Organism: | Drosophila melanogaster |
| Length: | 1993 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Sbf-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
1908.0 | [0..1] | [1993..1] |
|
Region A: Residues: [1-96] |
1 11 21 31 41 51
| | | | | |
1 MSRLADYFVI VGYDSDKEKT ASNVGGQPTC GKIVQRFPEK DWPDTPFIEG IEWFCQPLGW 60
61 SLSYEKQEPK FFVSVLTDID ANKHYCACLS FHETVA
|
| Detection Method: |  |
| Confidence: | 26.619789 |
| Match: | PF03456.9 |
| Description: | No description for PF03456.9 was found. |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [97-332] |
1 11 21 31 41 51
| | | | | |
1 ITQTRSVDDE DETIGSSRLL GATPSSMDGI TTTSTPASIT HHSVMYAPKC LVLISRLDCA 60
61 ETFKNCLGTI YTVYIENLAY GLETLIGNIL GCIQVPPAGG PQVRFSIGAG DKQSLQPPQS 120
121 SSLPTTGSGV HFLFKQLGIK NVLILLCSVM TENKILFLSK CYWHLTDSCR ALVALMYPFR 180
181 YTHVYIPILP APLTEVLSTP TPFIMGIHSS LQTEITDLLD VIVVDLDGGL VTIPES
|
| Detection Method: | |
| Confidence: | 62.136677 |
| Match: | PF02141.12 |
| Description: | No description for PF02141.12 was found. |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [333-458] |
1 11 21 31 41 51
| | | | | |
1 LTPPVPILPS PLWEQTQDLL SMILFPNLAQ ADLAFPTLER PSAIAKTDAQ IDKELRAIFM 60
61 RLFAQLLQGY RSCLTIIRIH PKPVITFHKA GFLGARDLIE SEFLFRVLDS MFFTTFVNER 120
121 GPPWRS
|
| Detection Method: | |
| Confidence: | 28.920819 |
| Match: | PF03455.10 |
| Description: | No description for PF03455.10 was found. |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [459-656] |
1 11 21 31 41 51
| | | | | |
1 SDAWDELYSS MNELLKSEAQ NRNLVGRTQR FKGYFNFTFP SYFQILTHIQ ELGRVLYENE 60
61 GTLAHISYAQ KVLRPPEGAF QRIHQPAFPR ISSEKVELII QEGIRKNGVP QRFHVTRNQH 120
121 RIIPMGPRLP EALDVRPNVQ NSARRLEVLR ICVSYIFENR ITDARKLLPA VMRTLMHRDA 180
181 RLILCREFFG YVHGNKAV
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [657-840] |
1 11 21 31 41 51
| | | | | |
1 LDHQQFELVV RFMNKALQKS SGIDEYTVAA ALLPMSTIFC RKLSTGVVQF AYTEIQDHAI 60
61 WKNLQFWEST FFQDVQGQIK ALYLLHRRQN EHQKEANCVL DEVPLEEPTA LEITAEQLRK 120
121 SPNIEEEKKA ELAKSEESTL YSQAIHFANR MVSLLIPLDV NVDAASKPKP AFRLEENQSV 180
181 SNSI
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [841-925] |
1 11 21 31 41 51
| | | | | |
1 MGSHSLSEHS DEGFEENNAL EIGVTVGKTI SRFIDCVCTE GGVTSEHIRN LHDMVPGVVH 60
61 MHIESLEPVY LEAKRHPHVQ KPKIQ
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [926-1022] |
1 11 21 31 41 51
| | | | | |
1 TPCLLPGEDL VTDHLRCFLM PDGREDETQC LIPAEGALFL TNYRVIFKGS PCDPLFCEQV 60
61 IVRTFPIASL LKEKKISVLY LAHLDQTLTE GLQLRSS
|
| Detection Method: | |
| Confidence: | 19.086186 |
| Match: | PF02893.11 |
| Description: | No description for PF02893.11 was found. |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1023-1660] |
1 11 21 31 41 51
| | | | | |
1 SFQLIKVAFD PEVTPEQIES FRKILSKARH PFDEFEYFAF QSYGTMLQGV APLKTKEKYS 60
61 TLKGFAKKTL LRGAKKAGFK QKQQTKRKLV SDYDYGSADA QETQSIDDEL EDGDEFETQN 120
121 NAMPRLLTTK DVERMRERSY VQDWKRLGFD AESQRGFRIS NANTSYATCR SYPAIIVAPV 180
181 QCSDAAIMHL GRCFKGQRIP LPTWRHANGA LLIRGGQPNS KSVIGMLKNT TGSTTNAHHD 240
241 VTHYPEQDKY FLALINTMPK LTPLALNQYS GMNLSMSSLM GHSSSDDRQP LTPELSRKHK 300
301 NNLDISDGNK SSQGGKGGTM KGNPKNSLAH PFRKMRLYAL GEKSQAKSNM NVDFCADFIP 360
361 VDYPDIRQSR PAFKKLIRAC MPSHNTNEAD GQSFAKMVEQ SDWLQQISSL MQLSGAVVDL 420
421 IDLQESSVML SLEDGSDVTA QLSSIAQLCL DPYYRSLDGF RVLVEKEWLA FGHRFAHRSN 480
481 LKPSHANTNI AFAPTFLQFL DVVHQLQRQF PMAFEFNDFY LRFLAYHSVS CRFRTFLFDC 540
541 ELERSDSGIA AMEDKRGSLN AKHMFGAGGM ATNGSDDECS VYPLDIRSQR APAPLNRIGH 600
601 SIFDYIERQH NKTPIFYNFL YSGDKSVTLR PQNNVAAL
|
| Detection Method: | |
| Confidence: | 144.0 |
| Match: | 1lw3A |
| Description: | Crystal Structure of Myotubularin-related protein 2 complexed with phosphate |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphoprotein phosphatase activity | 7.30669036331612 | bayes_pls_golite062009 |
| phosphatase activity | 6.53298300144214 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 6.34103372884365 | bayes_pls_golite062009 |
| protein tyrosine phosphatase activity | 5.71552511193227 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 5.10169989192986 | bayes_pls_golite062009 |
| hydrolase activity | 4.27459885320933 | bayes_pls_golite062009 |
| transmembrane receptor protein phosphatase activity | 4.08406741536367 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine phosphatase activity | 4.08406741536367 | bayes_pls_golite062009 |
| protein tyrosine/serine/threonine phosphatase activity | 2.7244435750389 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.46145625794727 | bayes_pls_golite062009 |
| receptor activity | 2.27569467096563 | bayes_pls_golite062009 |
| molecular transducer activity | 2.09373043968997 | bayes_pls_golite062009 |
| signal transducer activity | 2.09373043968997 | bayes_pls_golite062009 |
| protein serine/threonine phosphatase activity | 1.8743338569912 | bayes_pls_golite062009 |
| binding | 1.42026750513729 | bayes_pls_golite062009 |
| protein binding | 1.07441758584517 | bayes_pls_golite062009 |
| catalytic activity | 1.06283028154109 | bayes_pls_golite062009 |
| inositol or phosphatidylinositol phosphatase activity | 0.797185121839876 | bayes_pls_golite062009 |
| lipid phosphatase activity | 0.734449638967758 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 0.60269333716049 | bayes_pls_golite062009 |
| non-membrane spanning protein tyrosine phosphatase activity | 0.594382447716896 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.440408293428823 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 0.368252171155074 | bayes_pls_golite062009 |
| potassium channel activity | 0.33927808168843 | bayes_pls_golite062009 |
| channel activity | 0.29024318255551 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 0.29024318255551 | bayes_pls_golite062009 |
| substrate-specific channel activity | 0.274625894373147 | bayes_pls_golite062009 |
| gated channel activity | 0.217548650508289 | bayes_pls_golite062009 |
| ion channel activity | 0.207688369683596 | bayes_pls_golite062009 |
| cation channel activity | 0.125967756551725 | bayes_pls_golite062009 |
|
Region A: Residues: [1661-1868] |
1 11 21 31 41 51
| | | | | |
1 DLWCYYTNEE LAQGAPYDLE VTTVDDEIDL SETKGKRMVI TAGYDNMEKC NPSAYVCLLS 60
61 EVKQAETERG HLPQKWLQVW NSLEVPQLEP VARNTSLGNI FVQTHQHKRS TLEIIMKGRL 120
121 AGYQDKYFHP HRFEKHPYTT PTNCNHCTKL LWGPVGYRCM DCGNSYHEKC TEHSMKNCTK 180
181 YKAIDGAVGP PNVNMSQGDT ASIASSAA
|
| Detection Method: | |
| Confidence: | 15.221849 |
| Match: | 1xa6A |
| Description: | Crystal Structure of the Human Beta2-Chimaerin |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.15139804299723 | bayes_pls_golite062009 |
| signal transducer activity | 1.5242100351394 | bayes_pls_golite062009 |
| molecular transducer activity | 1.5242100351394 | bayes_pls_golite062009 |
| protein binding | 1.29100556128076 | bayes_pls_golite062009 |
| GTPase regulator activity | 0.507221182248837 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 0.482573970055889 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.473228380405599 | bayes_pls_golite062009 |
| kinase activity | 0.401449013594256 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.27531119327217 | bayes_pls_golite062009 |
| protein kinase activity | 0.266851843850147 | bayes_pls_golite062009 |
| catalytic activity | 0.194464246602439 | bayes_pls_golite062009 |
| lipid binding | 0.12073899779791 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.0539426578243308 | bayes_pls_golite062009 |
|
Region A: Residues: [1869-1993] |
1 11 21 31 41 51
| | | | | |
1 TTARTSSHHF YNQFSSNVAE NRTHEGHLYK RGALLKGWKQ RWFVLDSIKH QLRYYDTSED 60
61 TAPKGIIELA EVQSVTAAQP AQIGAKGVDE KGFFDLKTSK RIYNFYAINA NLAQEWIEKL 120
121 QACLQ
|
| Detection Method: | |
| Confidence: | 20.522879 |
| Match: | 1v5uA |
| Description: | Solution Structure of the C-terminal Pleckstrin Homology Domain of Sbf1 from Mouse |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.65091781683225 | bayes_pls_golite062009 |
| phosphoprotein phosphatase activity | 2.51186557035049 | bayes_pls_golite062009 |
| protein binding | 2.12168271674167 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 1.9018280968413 | bayes_pls_golite062009 |
| phosphatase activity | 1.90034030060323 | bayes_pls_golite062009 |
| molecular transducer activity | 1.82233415659529 | bayes_pls_golite062009 |
| signal transducer activity | 1.82233415659529 | bayes_pls_golite062009 |
| hydrolase activity | 1.72604953071036 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 1.23074471235333 | bayes_pls_golite062009 |
| receptor activity | 0.819319903902943 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.696394500650961 | bayes_pls_golite062009 |
| protein domain specific binding | 0.51731521446502 | bayes_pls_golite062009 |
| protein tyrosine phosphatase activity | 0.47102669930753 | bayes_pls_golite062009 |
| lipid binding | 0.12933186945671 | bayes_pls_golite062009 |
| receptor signaling protein activity | 0.0787973205518102 | bayes_pls_golite062009 |
| receptor binding | 0.0638301437766597 | bayes_pls_golite062009 |
| phospholipid binding | 0.0143594745448499 | bayes_pls_golite062009 |
