YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: Rel-PB, Rel-PC, ...
Organism: Drosophila melanogaster
Length: 971 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Rel-PB, Rel-PC, ....

Description E-value Query
Range
Subject
Range
gi|6636304 - gi|6636304|gb|AAF20136.1|AF204288_1 RELISH [Drosophila melanogaster]
619.0 [0..68] [880..1]

Back

Predicted Domain #1
Region A:
Residues: [1-93]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNMNQYYDLD NGKNVMFMND ASSTSGYSSS TSPNSTNRSF SPAHSPKTME LQTDFANLNL  60
   61 PGGNSPHQPP MANSPYQNQL LNNGGICQLG ATN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [94-456]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LINSTGVSFG VANVTSFGNM YMDHQYFVPA PATVPPSQNF GYHQNGLASD GDIKHVPQLR  60
   61 IVEQPVEKFR FRYKSEMHGT HGSLNGANSK RTPKTFPEVT LCNYDGPAVI RCSLFQTNLD 120
  121 SPHSHQLVVR KDDRDVCDPH DLHVSKERGY VAQFINMGII HTAKKYIFEE LCKKKQDRLV 180
  181 FQMNRRELSH KQLQELHQET EREAKDMNLN QVRLCFEAFK IEDNGAWVPL APPVYSNAIN 240
  241 NRKSAQTGEL RIVRLSKPTG GVMGNDELIL LVEKVSKKNI KVRFFEEDED GETVWEAYAK 300
  301 FRESDVHHQY AIVCQTPPYK DKDVDREVNV YIELIRPSDD ERSFPALPFR YKPRSVIVSR 360
  361 KRR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 108.0
Match: 1svcP
Description: p50 subunit of NF-kappa B transcription factor; p50 subunit of NF-kappa B (NFKB), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.42929256050781 bayes_pls_golite062009
DNA binding 5.31133900263778 bayes_pls_golite062009
nucleic acid binding 5.16722510757739 bayes_pls_golite062009
transcription factor activity 4.50526425463039 bayes_pls_golite062009
sequence-specific DNA binding 3.91938513552138 bayes_pls_golite062009
transcription activator activity 3.89749713667575 bayes_pls_golite062009
binding 3.82913410895101 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.14317875446423 bayes_pls_golite062009
protein binding 2.61625563263605 bayes_pls_golite062009
structure-specific DNA binding 1.87544096847314 bayes_pls_golite062009
DNA strand annealing activity 1.81456840545282 bayes_pls_golite062009
double-stranded DNA binding 1.68237504321416 bayes_pls_golite062009
single-stranded DNA binding 1.49080128448961 bayes_pls_golite062009
chromatin binding 1.28001279726096 bayes_pls_golite062009
transcription repressor activity 1.27337392672914 bayes_pls_golite062009
transcription factor binding 0.628837188707778 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 0.35905469882415 bayes_pls_golite062009
protein dimerization activity 0.0889583851427092 bayes_pls_golite062009
chitin binding 0.0880651619819113 bayes_pls_golite062009
ligand-gated ion channel activity 0.0676214219421661 bayes_pls_golite062009
ligand-gated channel activity 0.0676214219421661 bayes_pls_golite062009
cation channel activity 0.0318083563912285 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [457-543]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RTGSSANSSS SGTESSNNSL DLPKTLGLAQ PPNGLPNLSQ HDQTISEEFG REKHLNEFIA  60
   61 SEDFRKLIEH NSSDLEKICQ LDMGELQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
protein binding 2.69918165732603 bayes_pls_golite062009
binding 2.60916417202222 bayes_pls_golite062009
transcription regulator activity 2.37103377984038 bayes_pls_golite062009
nucleic acid binding 1.8957142857582 bayes_pls_golite062009
DNA binding 1.78305438715057 bayes_pls_golite062009
transcription activator activity 1.6418915400902 bayes_pls_golite062009
transcription factor activity 1.2667825651547 bayes_pls_golite062009
transcription factor binding 1.06366405671195 bayes_pls_golite062009
sequence-specific DNA binding 0.949906091645366 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.590503097160372 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [544-611]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HDGHNRAEVP SHRNRTIKCL DDLFEIYKQD RISPIKISHH KVEKWFIEHA LNNYNRDTLL  60
   61 HEVISHKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.69897
Match: 1sw6A
Description: Swi6 ankyrin-repeat fragment
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [612-971]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKLKLAIQTI QVMNYFNLKD VVNSTLNADG DSALHVACQQ DRAHYIRPLL GMGCNPNLKN  60
   61 NAGNTPLHVA VKEEHLSCVE SFLNGVPTVQ LDLSLTNDDG LTPLHMAIRQ NKYDVAKKLI 120
  121 SYDRTSISVA NTMDGNNALH MAVLEQSVEL LVLILDAQNE NLTDILQAQN AAGHTPLELA 180
  181 ERKANDRVVQ LLKNVYPEKG ELAMTWIPCK VKEEIDSSSD ESSDAGQLEI KSEEMDIETK 240
  241 DEDSVELDLS SGPRRQKDES SRDTEMDNNK LQLLLKNKFI YDRLCSLLNQ PLGHGSDPQD 300
  301 RKWMQLARQT HLKQFAFIWL GAEDLLDHVK RKGASVEFST FARALQAVDP QAYALLVNPT 360
  361 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 83.045757
Match: 1n11A
Description: Ankyrin-R
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 2.69918165732603 bayes_pls_golite062009
binding 2.60916417202222 bayes_pls_golite062009
transcription regulator activity 2.37103377984038 bayes_pls_golite062009
nucleic acid binding 1.8957142857582 bayes_pls_golite062009
DNA binding 1.78305438715057 bayes_pls_golite062009
transcription activator activity 1.6418915400902 bayes_pls_golite062009
transcription factor activity 1.2667825651547 bayes_pls_golite062009
transcription factor binding 1.06366405671195 bayes_pls_golite062009
sequence-specific DNA binding 0.949906091645366 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.590503097160372 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle