YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: Gnf1-PA
Organism: Drosophila melanogaster
Length: 986 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Gnf1-PA.

Description E-value Query
Range
Subject
Range
gi|304728 - gi|304728|gb|AAA28573.1| transcription factor [Drosophila melanogaster]
445.0 [0..1] [968..1]

Back

Predicted Domain #1
Region A:
Residues: [1-125]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQRGIDSFFK RLPAKAKSAE AENGETPSKA PKRRKAVIIS SDEDEVVSPP ETKKRKASKT  60
   61 ASSEDDVVAA TPEPIAKKAR NGQKPALSKL KRHVDPTELF GGETKRVIVP KPKTKAVLEF 120
  121 ENEDI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [126-224]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRSLMEVDLD ESIKEAAPEK KVHSITRSSP SPKRAKNSSP EPPKPKSTKS KATTPRVKKE  60
   61 KPAADLESSV LTDEERHERK RASAVLYQKY KNRSSCLNP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.0
Match: 2aneA
Description: Crystal structure of N-terminal domain of E.Coli Lon Protease
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.16354923842292 bayes_pls_golite062009
nucleic acid binding 1.15712369152434 bayes_pls_golite062009
transcription regulator activity 1.01821010146225 bayes_pls_golite062009
DNA binding 0.851165739361333 bayes_pls_golite062009
transcription factor activity 0.219534193320134 bayes_pls_golite062009
catalytic activity 0.147263815852997 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [225-402]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSKEIPKGSP DCLSGLTFVV TGVLESMERE EAESVIKEYG GKVMTVVGKK LKYLVVGEEA  60
   61 GPKKLAVAEE LNIPILSEDG LFDLIREKSG IAKQVKEEKK SPKKEHSSEE KGKKEVKTSR 120
  121 RSSDKKEKEA TKLKYGEKHD IAKHKVKEEH TSPKETKDKL NDVPAVTLKV KKEPSSQK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.045757
Match: 1qvrA
Description: Crystal Structure Analysis of ClpB
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [403-907]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EHPPSPRTAD LKTLDVVGMA WVDKHKPTSI KEIVGQAGAA SNVTKLMNWL SKWYVNHDGN  60
   61 KKPQRPNPWA KNDDGSFYKA ALLSGPPGIG KTTTATLVVK ELGFDAVEFN ASDTRSKRLL 120
  121 KDEVSTLLSN KSLSGYFTGQ GQAVSRKHVL IMDEVDGMAG NEDRGGMQEL IALIKDSSIP 180
  181 IICMCNDRNH PKIRSLVNYC YDLRFQRPRL EQIKGKIMSI CFKEKVKISP AKVEEIIAAT 240
  241 NNDIRQSINH IALLSAKEDA SQKSGQQVAT KDLKLGPWEV VRKVFTADEH KHMSFADKSD 300
  301 LFFHDYSLAP LFVQQNYLQV LPQGNKKDVL AKVAATADAL SLGDLVEKRI RANSAWSLLP 360
  361 TQAFFSSVLP GEHMCGHFTG QINFPGWLGK NSKSGKRARL AQELHDHTRV CTSGSRLSVR 420
  421 LDYAPFLLDN IVRPLAKDGQ EGVPAALDVM KDYHLLREDL DSLVELTSWP GKKSPLDAVD 480
  481 GRVKAALTRS YNKEVMAYSY SAQAG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 54.69897
Match: 1sxjA
Description: Crystal Structure of the Eukaryotic Clamp Loader (Replication Factor C, RFC) Bound to the DNA Sliding Clamp (Proliferating Cell Nuclear Antigen, PCNA)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA clamp loader activity 5.5471162885167 bayes_pls_golite062009
protein-DNA loading ATPase activity 5.51408792884858 bayes_pls_golite062009
DNA-dependent ATPase activity 2.72462789867829 bayes_pls_golite062009
DNA helicase activity 2.2817164193758 bayes_pls_golite062009
pyrophosphatase activity 2.13284212711072 bayes_pls_golite062009
binding 2.05253348982328 bayes_pls_golite062009
ATP-dependent DNA helicase activity 1.88455339138556 bayes_pls_golite062009
nucleic acid binding 1.49633029954726 bayes_pls_golite062009
helicase activity 1.16085745407703 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
DNA-directed DNA polymerase activity 0.971476020912368 bayes_pls_golite062009
DNA binding 0.967303417236485 bayes_pls_golite062009
DNA polymerase activity 0.928091843881235 bayes_pls_golite062009
transcription regulator activity 0.748437190903548 bayes_pls_golite062009
purine NTP-dependent helicase activity 0.59513742813869 bayes_pls_golite062009
ATP-dependent helicase activity 0.59513742813869 bayes_pls_golite062009
structure-specific DNA binding 0.249173645231486 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.147579541298736 bayes_pls_golite062009
nucleotide binding 0.114848452385726 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.113504049290503 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.111293884322157 bayes_pls_golite062009
purine nucleotide binding 0.10713474095071 bayes_pls_golite062009
purine ribonucleotide binding 0.0916519414118148 bayes_pls_golite062009
ribonucleotide binding 0.0915913646217636 bayes_pls_golite062009
structural constituent of ribosome 0.089234257580272 bayes_pls_golite062009
double-stranded DNA binding 0.0781650226500197 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [908-986]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IKKKKSEAAG ADDDYLDEGP GEEDGAGGHL SSEEDEDKDN LELDSLIKAK KRTTTSKASG  60
   61 GSKKATSSTA SKSKAKAKK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle