YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: Orc4-PA
Organism: Drosophila melanogaster
Length: 459 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Orc4-PA.

Description E-value Query
Range
Subject
Range
gi|25308071 - pir||AI3294 cell division protein ftsH (EC 3.4.24.-) [imported] - Brucella melitensis (strain 16M)
gi|17982240, gi|... - gi|17986626|ref|NP_539260.1| cell division protein FTSH [Brucella melitensis 16M], gi|17982240|gb|AA...
321.0 [0..9] [455..149]

Back

Predicted Domain #1
Region A:
Residues: [1-459]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPEADRELVS IRRFLKERLQ RDYTTLRGYA KERSNVRLLL QRTAEMGESN SLLLLGPRGS  60
   61 GKTTLINSVL ADLLPNKSFG ENTLIVHLDG NLHTDDRVAL KSITVQMQLE NAADGKVFGS 120
  121 FAENLAFLLQ CLKAGGKHSK SVIFILEEFD LFCAHHNQTL LYNLFDVSQS AQAPICVLGV 180
  181 TCRLDVIELL EKRVKSRFSH RQVFLFPSLR RFEDYVDLCR DLLSLPTGNS LLLAAEKIYN 240
  241 LQNIQSGALY FSRNHFDPGE YGFSPRLRDA WNKQICKVLA TQQARSTLQA LHDFDISEAY 300
  301 LKNFLFRLVA HLRPQSPHIT AEKMAAVGSQ FEGDDKIELL CGLSVLELCL IIAIKHHSQI 360
  361 YDRDSFNFEI IYARFSKFAK VSTTMQAVER SIVLKAFEHL RIAELIMPLT GGAGGGVGKV 420
  421 QKEFEMHKLA LTYSQIHHCM QRYQALPTEV AQWAQSSLI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 72.0
Match: 2ce7A
Description: EDTA treated
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA clamp loader activity 3.22518920754305 bayes_pls_golite062009
protein-DNA loading ATPase activity 3.19273435123154 bayes_pls_golite062009
DNA-dependent ATPase activity 2.72462789867829 bayes_pls_golite062009
DNA helicase activity 2.2817164193758 bayes_pls_golite062009
pyrophosphatase activity 2.13284212711072 bayes_pls_golite062009
binding 2.05253348982328 bayes_pls_golite062009
ATP-dependent DNA helicase activity 1.88455339138556 bayes_pls_golite062009
helicase activity 1.70242731830224 bayes_pls_golite062009
DNA replication origin binding 1.62491387774159 bayes_pls_golite062009
nucleic acid binding 1.49633029954726 bayes_pls_golite062009
purine NTP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
ATP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
DNA-directed DNA polymerase activity 0.971476020912368 bayes_pls_golite062009
DNA binding 0.967303417236485 bayes_pls_golite062009
DNA polymerase activity 0.928091843881235 bayes_pls_golite062009
structure-specific DNA binding 0.782430219754236 bayes_pls_golite062009
transcription regulator activity 0.748437190903548 bayes_pls_golite062009
double-stranded DNA binding 0.6071273686445 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.147579541298736 bayes_pls_golite062009
nucleotide binding 0.114848452385726 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.113504049290503 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.111293884322157 bayes_pls_golite062009
purine nucleotide binding 0.10713474095071 bayes_pls_golite062009
purine ribonucleotide binding 0.0916519414118148 bayes_pls_golite062009
ribonucleotide binding 0.0915913646217636 bayes_pls_golite062009
structural constituent of ribosome 0.089234257580272 bayes_pls_golite062009
3'-5' DNA helicase activity 0.0769112340058804 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle