| Protein: | fab1-PB, fab1-PA |
| Organism: | Drosophila melanogaster |
| Length: | 1809 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for fab1-PB, fab1-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
1447.0 | [0..11] | [1809..51] |
|
Region A: Residues: [1-80] |
1 11 21 31 41 51
| | | | | |
1 MTSNNQNNSS SHQHLHSPSK LTEFARNFED KPESLFGRVV NKIQNVYNQS YNTVNDISSG 60
61 SSSSSSTQPV QVVGKSQFFS
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [81-254] |
1 11 21 31 41 51
| | | | | |
1 DSQTSTAEIA DVETSSQSSV RPQPPTTLSI RTNSETRGTS TSSNTAAEDS ETSDRVETLP 60
61 LPTSEANQGR TVSNVLKHIS NIVATKNNND LRNYKDTELQ RFWMPDSKAK ECYDCSQKFS 120
121 TFRRKHHCRL CGQIFCSKCC NQVVPGMIIR CDGDLKVCNY CSKIVLTFLK SSSS
|
| Detection Method: | |
| Confidence: | 24.0 |
| Match: | 1dvpA |
| Description: | Hrs |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| clathrin binding | 4.42433208284373 | bayes_pls_golite062009 |
| binding | 2.50482426575478 | bayes_pls_golite062009 |
| protein transporter activity | 1.56162306597345 | bayes_pls_golite062009 |
| phosphoinositide binding | 1.5307798253901 | bayes_pls_golite062009 |
| protein binding | 1.42349040268084 | bayes_pls_golite062009 |
| phospholipid binding | 1.34712325037196 | bayes_pls_golite062009 |
| transporter activity | 1.32696426532114 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.679696382592776 | bayes_pls_golite062009 |
| phosphatidylinositol binding | 0.67214549237381 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.578667797495151 | bayes_pls_golite062009 |
| kinase activity | 0.5474180136682 | bayes_pls_golite062009 |
| transcription regulator activity | 0.514683355576285 | bayes_pls_golite062009 |
| DNA binding | 0.443878702795963 | bayes_pls_golite062009 |
| protein kinase activity | 0.433946621843553 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.374880899986848 | bayes_pls_golite062009 |
| nucleic acid binding | 0.310675378998881 | bayes_pls_golite062009 |
| lipid binding | 0.131242568396849 | bayes_pls_golite062009 |
|
Region A: Residues: [255-325] |
1 11 21 31 41 51
| | | | | |
1 EMGQDMQELQ QHLSNKLEVQ DSGSSLAKHP QMQRAPLPRK TSVGYQEERF SSHPTYTTLS 60
61 IDDRKNILQQ S
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [326-824] |
1 11 21 31 41 51
| | | | | |
1 NSLITLHEEM QRDLPAQNCG QRLIEFLNSN NKSANEVQAV AILNAMLAAG FLEPIVPDPE 60
61 QMDFDSSLHY KFSKSSSSDT SRTMSPQFEA NPHAEPQPPK SMDQSAEEKE KELENELEND 120
121 RCYTTATSKL LASYCEHEEQ LLAQMLRAHN LDQEWDKVLQ MLCSTAANHF KPEHCSNDLM 180
181 DIRNYVNFKK VPGGRRKDSK IVHGVAFSKN VAHKDMATHV PFPRILLLQC PIVYERIEGK 240
241 FVTIETVLLQ EKEYLRNVCA RIMSFKPNVV LVHKNVAGIA QDLLRSYEVT LVLDVKLSVM 300
301 ERLSRTLQCD IVSSIESNIT MPKLGYCNDF YIRNYNGKTL MFFEKLTNPR GYTCLLRGGS 360
361 NAELTRVKRV ASALLFARYN WRLEMSFLLN EFAQPLSPKP SIFDSKETSP KTETEAELRS 420
421 KRPIILERKS EDKITTIVSE NVSDFTDPLR ASQAEALSTS PCAPPVVEAL AVEPRYDNRF 480
481 RTALSSTLLS VSPFLTFPL
|
| Detection Method: | |
| Confidence: | 119.0 |
| Match: | 1q3rA |
| Description: | Crystal structure of the chaperonin from Thermococcus strain KS-1 (nucleotide-free form of single mutant) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| 1-phosphatidylinositol-4-phosphate 5-kinase activity | 2.0792241139321 | bayes_pls_golite062009 |
| binding | 1.64221234725269 | bayes_pls_golite062009 |
| lipid kinase activity | 1.30654443346559 | bayes_pls_golite062009 |
| transporter activity | 1.27879339110564 | bayes_pls_golite062009 |
| phosphatidylinositol phosphate kinase activity | 1.1532371074226 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.08697283907212 | bayes_pls_golite062009 |
| inositol or phosphatidylinositol kinase activity | 0.957759029487778 | bayes_pls_golite062009 |
| protein binding | 0.634982583867058 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.609181214178764 | bayes_pls_golite062009 |
| ATPase activity, coupled | 0.598076132132183 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.574104967364845 | bayes_pls_golite062009 |
| kinase activity | 0.56493424031677 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.543285791401512 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.493047135752617 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.479464705542409 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.477091093800976 | bayes_pls_golite062009 |
| ATPase activity | 0.451768217507419 | bayes_pls_golite062009 |
| catalytic activity | 0.424959044318554 | bayes_pls_golite062009 |
| protein transporter activity | 0.376915036228384 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.374469998972096 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.328059756322186 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 0.275534581026027 | bayes_pls_golite062009 |
| ATP binding | 0.204730002730195 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 0.181053338705642 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 0.178399335304171 | bayes_pls_golite062009 |
| nucleotide binding | 0.042857134831875 | bayes_pls_golite062009 |
| purine nucleotide binding | 0.0388218369124319 | bayes_pls_golite062009 |
| ribonucleotide binding | 0.0360954574704979 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 0.0333062688414986 | bayes_pls_golite062009 |
| primary active transmembrane transporter activity | 0.0312484818338645 | bayes_pls_golite062009 |
| P-P-bond-hydrolysis-driven transmembrane transporter activity | 0.0253141528618308 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.00800704157757948 | bayes_pls_golite062009 |
|
Region A: Residues: [825-939] |
1 11 21 31 41 51
| | | | | |
1 PYLETEQGRK CKLRKLFPAE LYFSKQWSRT GLERPDSMGD GEAGKSEPGN KENQMQLLPA 60
61 HDFVLMKITA PASSRDIQSK LAEFRSFGGR LPKGKAPMLR PKKKNAEVIQ RPQKV
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [940-1083] |
1 11 21 31 41 51
| | | | | |
1 SEEQLYKDAL DPQNHQRLPV LFCSFHYNPK GVSSFCKLPM LLDMKFYGQY DIMLEQFLQR 60
61 YCCLFNSMCP SCNLPMLGHV RRYVHSLGCV HVYLTEDLTR SDPTRIYFTS WCSICNATTP 120
121 TIPLSDAAKC LSLAKYLEMR FHGH
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1084-1256] |
1 11 21 31 41 51
| | | | | |
1 AYKRRPPSTD AEQGGTVCEH SLHRDYVHHF SFRGVGAKFQ YTPVEVWETD LPSLTVQLDL 60
61 PQPFQSAQVQ EEIKNFSIKG HEVYNRIHER IADLATEEEN SPLVQHLKTM LTHDQFIFKQ 120
121 KIEIVHTLLT DNRATAYDTS DALAMARRAL AESIELWGPR LQEIEKLTAK QAH
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1257-1487] |
1 11 21 31 41 51
| | | | | |
1 HIDSGTICTE ELRPEQVQTA DSSKVTTSSL PKENDPLECP SEDTETGASN SQTVLDKNFS 60
61 IDQMLASTVN VYSDKKSIRK ILTQLLPSGN QVNPLQSPFP AQDHLTLPLG SIPIHVRETD 120
121 LSSVIAYSLT SMDYQKAIDE AEANSNAAHS SPQLKRKIPL AESVSDAEDS PSLSRTSSNT 180
181 SAAPNASVPS PATAASESEE KSKERIKQPP SPHITLAFQD HSCQFQCKIY F
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1488-1734] |
1 11 21 31 41 51
| | | | | |
1 AREFDAMRSK SLKPPKLDKS LYRRLEKSKM REELRISQSR TGSEMELVRK PSDVGAPRTT 60
61 EDDSNQEEDA RIALARSLCK SVQWEARGGK SGSRFCKTLD DRFVLKEMNS RDMTIFEPFA 120
121 PKYFEYIDRC QQQQQPTLLA KIFGVFRVSV KKKDSFVERS VMVMENLFYG CNIENKFDLK 180
181 GSERNRLVDP SNQQGEIVLL DENLVQMSWS KPLYVLSHSK TVLRDAIQRD SSFLEKNLVM 240
241 DYSLLVG
|
| Detection Method: | |
| Confidence: | 63.30103 |
| Match: | 1bo1A |
| Description: | Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| 1-phosphatidylinositol-4-phosphate 5-kinase activity | 4.78387945404586 | bayes_pls_golite062009 |
| inositol or phosphatidylinositol kinase activity | 4.31726963575315 | bayes_pls_golite062009 |
| lipid kinase activity | 3.63026201392483 | bayes_pls_golite062009 |
| phosphatidylinositol phosphate kinase activity | 3.5005619620026 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 2.8512866333787 | bayes_pls_golite062009 |
| kinase activity | 2.68971389233526 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 2.31077377326314 | bayes_pls_golite062009 |
| catalytic activity | 1.87792712964225 | bayes_pls_golite062009 |
| binding | 1.23659721062619 | bayes_pls_golite062009 |
| transferase activity | 1.20817067352467 | bayes_pls_golite062009 |
| signal transducer activity | 0.702573274403091 | bayes_pls_golite062009 |
| molecular transducer activity | 0.702573274403091 | bayes_pls_golite062009 |
| ligase activity | 0.435608917599349 | bayes_pls_golite062009 |
| protein kinase activity | 0.422676745032915 | bayes_pls_golite062009 |
| protein binding | 0.382966234080422 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.189737258618863 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 0.14608192065514 | bayes_pls_golite062009 |
|
Region A: Residues: [1735-1809] |
1 11 21 31 41 51
| | | | | |
1 LDKKNGVLVL GIIDYIRTFT LDKRVESIIK GSGILGGKGK DPTVVNPERY KQRFIDAMDR 60
61 YFLTVPDRWE GLSKV
|
| Detection Method: | |
| Confidence: | 3.09 |
| Match: | 2gk9A |
| Description: | No description for 2gk9A was found. |
