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Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor). Catalysis of the phosphorylation of phosphatidylinositol phosphate to produce phosphatidylinositol bisphosphate. Catalysis of the phosphorylation of a simple or complex lipid. Catalysis of the phosphorylation of myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol. Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: 1-phosphatidylinositol-4-phosphate 5-kinase activity
Acc: GO:0016308
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
Synonyms:
  • 1-phosphatidylinositol-4-phosphate kinase, class IB
  • PIP kinase activity
  • 1-phosphatidylinositol-4-phosphate kinase, class IA
  • PIP5K
  • diphosphoinositide kinase activity
  • type I PIP kinase activity
  • GO:0045215
  • GO:0004431
  • PtdIns(4)P-5-kinase activity
  • 1-phosphatidylinositol-4-phosphate kinase activity
  • phosphatidylinositol-4-phosphate 5-kinase activity
  • phosphatidylinositol 4-phosphate kinase activity
  • ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 5-phosphotransferase activity
Proteins in PDR annotated with:
   This term: 38 [Search]
   Term or descendants: 38 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0016308 - 1-phosphatidylinositol-4-phosphate 5-kinase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle