| Protein: | FBpp0294043, AGO... |
| Organism: | Drosophila melanogaster |
| Length: | 984 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0294043, AGO....
| Description | E-value | Query Range |
Subject Range |
|
|
1134.0 | [0..1] | [984..1] |
|
Region A: Residues: [1-140] |
1 11 21 31 41 51
| | | | | |
1 MSTERELAPG GPAQLHPHTL PLTFPDLQMT STVGIIGKVY ESQWTPSPTR PQSPSQAQTS 60
61 FDTLTSPPAP GSSVNPTAVT SPSAQNVAAG GATVAGAAAT AAQVASALGA TTGSVTPAIA 120
121 TATPATQPDM PVFTCPRRPN
|
| Detection Method: |  |
| Confidence: | 7.69897 |
| Match: | 1y0fA |
| Description: | No description for 1y0fA was found. |
|
Region A: Residues: [141-335] |
1 11 21 31 41 51
| | | | | |
1 LGREGRPIVL RANHFQVTMP RGYVHHYDIN IQPDKCPRKV NREIIETMVH AYSKIFGVLK 60
61 PVFDGRNNLY TRDPLPIGNE RLELEVTLPG EGKDRIFRVT IKWQAQVSLF NLEEALEGRT 120
121 RQIPYDAILA LDVVMRHLPS MTYTPVGRSF FSSPEGYYHP LGGGREVWFG FHQSVRPSQW 180
181 KMMLNIDVSA TAFYK
|
| Detection Method: | |
| Confidence: | 3.35 |
| Match: | 1u04A |
| Description: | Crystal structure of full length Argonaute from Pyrococcus furiosus |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [336-536] |
1 11 21 31 41 51
| | | | | |
1 AQPVIDFMCE VLDIRDINEQ RKPLTDSQRV KFTKEIKGLK IEITHCGQMR RKYRVCNVTR 60
61 RPAQMQSFPL QLENGQTVEC TVAKYFLDKY RMKLRYPHLP CLQVGQEHKH TYLPLEVCNI 120
121 VAGQRCIKKL TDMQTSTMIK ATARSAPDRE REINNLVKRA DFNNDSYVQE FGLTISNSMM 180
181 EVRGRVLPPP KLQYGGRVST G
|
| Detection Method: | |
| Confidence: | 52.0 |
| Match: | 1r4kA |
| Description: | Solution Structure of the Drosophila Argonaute 1 PAZ Domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| miRNA binding | 8.69268950569308 | bayes_pls_golite062009 |
| RNA cap binding | 6.0791415062122 | bayes_pls_golite062009 |
| translation initiation factor activity | 5.50078893654345 | bayes_pls_golite062009 |
| RNA 7-methylguanosine cap binding | 5.43471478554516 | bayes_pls_golite062009 |
| siRNA binding | 4.26412929341885 | bayes_pls_golite062009 |
| RNA binding | 4.23761892485628 | bayes_pls_golite062009 |
| nucleic acid binding | 2.70139792513064 | bayes_pls_golite062009 |
| binding | 2.52855691585079 | bayes_pls_golite062009 |
| protein binding | 2.40440976820485 | bayes_pls_golite062009 |
| ribonuclease activity | 1.7851440901313 | bayes_pls_golite062009 |
| translation regulator activity | 1.24691427875148 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 1.22763794139559 | bayes_pls_golite062009 |
| hydrolase activity | 0.761541237875448 | bayes_pls_golite062009 |
| catalytic activity | 0.276917867171685 | bayes_pls_golite062009 |
|
Region A: Residues: [537-984] |
1 11 21 31 41 51
| | | | | |
1 LTGQQLFPPQ NKVSLASPNQ GVWDMRGKQF FTGVEIRIWA IACFAPQRTV REDALRNFTQ 60
61 QLQKISNDAG MPIIGQPCFC KYATGPDQVE PMFRYLKITF PGLQLVVVVL PGKTPVYAEV 120
121 KRVGDTVLGM ATQCVQAKNV NKTSPQTLSN LCLKINVKLG GINSILVPSI RPKVFNEPVI 180
181 FLGADVTHPP AGDNKKPSIA AVVGSMDAHP SRYAATVRVQ QHRQEIIQEL SSMVRELLIM 240
241 FYKSTGGYKP HRIILYRDGV SEGQFPHVLQ HELTAIREAC IKLEPEYRPG ITFIVVQKRH 300
301 HTRLFCAEKK EQSGKSGNIP AGTTVDVGIT HPTEFDFYLC SHQGIQGTSR PSHYHVLWDD 360
361 NHFDSDELQC LTYQLCHTYV RCTRSVSIPA PAYYAHLVAF RARYHLVEKE HDSGEGSHQS 420
421 GCSEDRTPGA MARAITVHAD TKKVMYFA
|
| Detection Method: | |
| Confidence: | 10.39794 |
| Match: | 1w9hA |
| Description: | The Structure of a Piwi protein from Archaeoglobus fulgidus. |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| ribonuclease activity | 5.30591758406946 | bayes_pls_golite062009 |
| ribonuclease III activity | 4.20335726467076 | bayes_pls_golite062009 |
| 4.10363762148891 | bayes_pls_golite062009 | |
| exoribonuclease activity | 3.71639182685131 | bayes_pls_golite062009 |
| exoribonuclease activity, producing 5'-phosphomonoesters | 3.59362615133405 | bayes_pls_golite062009 |
| exonuclease activity | 3.13676176369406 | bayes_pls_golite062009 |
| nuclease activity | 3.11657409772275 | bayes_pls_golite062009 |
| RNA binding | 3.01997241125209 | bayes_pls_golite062009 |
| transposase activity | 2.97988408226992 | bayes_pls_golite062009 |
| ribonuclease H activity | 2.91966688044755 | bayes_pls_golite062009 |
| hydrolase activity | 2.78602644579272 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 2.70794511869438 | bayes_pls_golite062009 |
| endonuclease activity | 2.63074055051349 | bayes_pls_golite062009 |
| endoribonuclease activity | 2.59247838057313 | bayes_pls_golite062009 |
| transcription regulator activity | 2.20855917457806 | bayes_pls_golite062009 |
| nucleic acid binding | 2.14285769817394 | bayes_pls_golite062009 |
| 3'-5'-exoribonuclease activity | 2.12039058720352 | bayes_pls_golite062009 |
| exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 1.94077739152313 | bayes_pls_golite062009 |
| deoxyribonuclease activity | 1.87431870698721 | bayes_pls_golite062009 |
| DNA binding | 1.86594005896134 | bayes_pls_golite062009 |
| endoribonuclease activity, producing 5'-phosphomonoesters | 1.74431545836806 | bayes_pls_golite062009 |
| DNA polymerase activity | 1.64519652804477 | bayes_pls_golite062009 |
| endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 1.59628511603826 | bayes_pls_golite062009 |
| DNA-directed DNA polymerase activity | 1.54576601235316 | bayes_pls_golite062009 |
| 3'-5' exonuclease activity | 1.44123900197846 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 1.363399194272 | bayes_pls_golite062009 |
| binding | 1.35497934205068 | bayes_pls_golite062009 |
| catalytic activity | 1.25233849524628 | bayes_pls_golite062009 |
| transcription activator activity | 1.1830013572628 | bayes_pls_golite062009 |
| transcription factor activity | 1.17659544650821 | bayes_pls_golite062009 |
| mRNA binding | 1.10473275263716 | bayes_pls_golite062009 |
| protein binding | 1.08578027658199 | bayes_pls_golite062009 |
| exodeoxyribonuclease activity, producing 5'-phosphomonoesters | 0.782108781904855 | bayes_pls_golite062009 |
| exodeoxyribonuclease activity | 0.77421125364834 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.599626528449085 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.58055486321736 | bayes_pls_golite062009 |
| kinase activity | 0.557302038379807 | bayes_pls_golite062009 |
| endodeoxyribonuclease activity | 0.48776342704945 | bayes_pls_golite062009 |
| protein kinase activity | 0.354993329967566 | bayes_pls_golite062009 |
| DNA helicase activity | 0.283883977748512 | bayes_pls_golite062009 |
| double-stranded RNA-specific ribonuclease activity | 0.222737597484808 | bayes_pls_golite062009 |
| transferase activity | 0.0868471791986259 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.0701825322473915 | bayes_pls_golite062009 |
