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View Structure Prediction Details

Protein: CG42347-PB
Organism: Drosophila melanogaster
Length: 446 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG42347-PB.

Description E-value Query
Range
Subject
Range
gi|14029712 - gi|14029712|gb|AAK52801.1|AF363784_1 calcium-dependent protein kinase CDPK1 [Lycopersicon esculentum...
353.0 [0..8] [446..47]

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Predicted Domain #1
Region A:
Residues: [1-339]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIYIDDSEPE GVLEPAFPMR DVTINRNVDA HKHYDVLGEV GRGKFGTVYK CRDKANGLQL  60
   61 AAKFVPIPKR EDKRNVEREV EIMNSLQHHL IIQLYAAYEY QKMMCVVLEL IEGGELFDRV 120
  121 VDDEFVLTER VCRVFIRQVC EAMAFIHGNG IVHLDLKPEN ILVLTQKGNR IKIIDFGLAR 180
  181 KFDPDKRLRV LFGTPEFVAP EVVNFDCISY GTDMWSVGVI CYVLISGLSP FMGENDIETM 240
  241 SNVTIAKYDF EDECFNGISP ECLDFIAKLL AKDLSTRMTA AECMKHKWLQ QRPATAATAT 300
  301 PITKAASAAS KSRLKSVSPV TAPSESSEDS TETIEDEDD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 63.30103
Match: 1kobA
Description: Twitchin, kinase domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphotransferase activity, alcohol group as acceptor 5.49988294224815 bayes_pls_golite062009
protein kinase activity 5.4586557943719 bayes_pls_golite062009
kinase activity 5.3287080791198 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.96052051118534 bayes_pls_golite062009
protein serine/threonine kinase activity 4.46381887831481 bayes_pls_golite062009
transferase activity 3.97138602499442 bayes_pls_golite062009
binding 2.74863538127007 bayes_pls_golite062009
tubulin binding 2.18641675163967 bayes_pls_golite062009
cytoskeletal protein binding 2.12615078788254 bayes_pls_golite062009
ATP binding 1.97600611746091 bayes_pls_golite062009
adenyl ribonucleotide binding 1.93596671856664 bayes_pls_golite062009
adenyl nucleotide binding 1.90928021591891 bayes_pls_golite062009
microtubule binding 1.88110801192607 bayes_pls_golite062009
purine ribonucleotide binding 1.65732943334212 bayes_pls_golite062009
ribonucleotide binding 1.65726906484847 bayes_pls_golite062009
purine nucleotide binding 1.63763394711025 bayes_pls_golite062009
nucleotide binding 1.63195828048121 bayes_pls_golite062009
protein tyrosine kinase activity 1.3898059094397 bayes_pls_golite062009
receptor signaling protein serine/threonine kinase activity 1.38496328649031 bayes_pls_golite062009
actin binding 1.33479685165255 bayes_pls_golite062009
gamma-tubulin binding 1.28511591054866 bayes_pls_golite062009
receptor signaling protein activity 1.27291233344322 bayes_pls_golite062009
protein binding 1.22565748038754 bayes_pls_golite062009
catalytic activity 1.21655087018101 bayes_pls_golite062009
structural constituent of cytoskeleton 0.612883428421652 bayes_pls_golite062009
cyclin-dependent protein kinase activity 0.499492353295369 bayes_pls_golite062009
protein serine/threonine/tyrosine kinase activity 0.48345772948903 bayes_pls_golite062009
magnesium ion binding 0.393328812780268 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.391384757497683 bayes_pls_golite062009
MAP kinase kinase kinase activity 0.37115026509016 bayes_pls_golite062009
MAP kinase kinase activity 0.35402045013148 bayes_pls_golite062009
pyrophosphatase activity 0.351206771811872 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.340617390162297 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.339969855367828 bayes_pls_golite062009
signal transducer activity 0.270054246024761 bayes_pls_golite062009
molecular transducer activity 0.270054246024761 bayes_pls_golite062009
actin filament binding 0.2403700250846 bayes_pls_golite062009
MAP kinase activity 0.08504542461349 bayes_pls_golite062009
transmembrane receptor protein kinase activity 0.0556163711947139 bayes_pls_golite062009
transmembrane receptor activity 0.00652065412910241 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [340-446]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEEVAVQQAK QKDQQQDEEL ANLCGDAELE NKELDATKDN LKNFIVRWET HPNSPYVFDV  60
   61 EGNVIAPLSE TSYPHPRRTH GADSLSSSRG EYGSQRQRDR HALIHGK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.045757
Match: 2aaoA
Description: Regulatory apparatus of Calcium Dependent protein kinase from Arabidopsis thaliana
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
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