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View Structure Prediction Details

Protein: tor-PA
Organism: Drosophila melanogaster
Length: 923 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tor-PA.

Description E-value Query
Range		 Subject
Range
gi|226322 - gi|226322|prf||1506439A torso gene
gi|125724, gi|60... - pir||S03900 gene torso protein precursor - fruit fly (Drosophila melanogaster), gi|603810|emb|CAA33...
 542.0 [0..1] [923..1]

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Predicted Domain #1
Region A:
Residues: [1-63] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLIFYAKYAF IFWFFVGSNQ GEMLLMDKIS HDKTLLNVTA CTQNCLEKGQ MDFRSCLKDC  60
   61 RIN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.0
Match: 2nziA
Description: No description for 2nziA was found.

Predicted Domain #2
Region A:
Residues: [64-455] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTFPGALRKV QENYQMNMIC RTESEIVFQI DWVQHSRGTE PAPNATYIIR VDAVKDDNKE  60
   61 TALYLSDDNF LILPGLESNS THNITALAMH GDGSYSLIAK DQTFATLIRG YQPSKMGAVN 120
  121 LLRFVPQPDD LHHIAAEIEW KPSAESNCYF DMVSYSTNSV NMDEPLEVQF RDRKKLYRHT 180
  181 VDNLEFDKQY HVGVRTVNIM NRLESDLQWL PIAVPSCLDW YPYNYTLCPP HKPENLTVTQ 240
  241 KQYLPNILAL NITWARPRYL PDNYTLHIFD LFKGGTELNY TLDQNRSHFY VPKITVLGSH 300
  301 FEVHLVAQSA GGKNVSGLTL DKVHRGVLLS EGNMVKLVLF IIVPICCILM LCSLTFCRRN 360
  361 RSEVQALQMD AKDAKASEFH LSLMDSSGLL VT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.09691
Match: 2dtgE
Description: No description for 2dtgE was found.

Predicted functions:

Term Confidence Notes
PTB domain binding 7.59954514905135 bayes_pls_golite062009
insulin receptor activity 5.32497038633998 bayes_pls_golite062009
transmembrane receptor activity 4.81256300373074 bayes_pls_golite062009
interleukin-6 binding 4.7755079145617 bayes_pls_golite062009
interleukin-6 receptor activity 4.7755079145617 bayes_pls_golite062009
receptor activity 4.66147271961356 bayes_pls_golite062009
molecular transducer activity 3.69234048247377 bayes_pls_golite062009
signal transducer activity 3.69234048247377 bayes_pls_golite062009
ciliary neurotrophic factor receptor activity 3.63622123190665 bayes_pls_golite062009
protein binding 3.24522318184038 bayes_pls_golite062009
oncostatin-M receptor activity 3.21526092940028 bayes_pls_golite062009
leukemia inhibitory factor receptor activity 3.21526092940028 bayes_pls_golite062009
cytokine binding 3.21238178184503 bayes_pls_golite062009
binding 3.12471204223368 bayes_pls_golite062009
SH2 domain binding 3.02533711127154 bayes_pls_golite062009
growth factor binding 2.99437744892471 bayes_pls_golite062009
ciliary neurotrophic factor receptor binding 2.79717898377819 bayes_pls_golite062009
cytokine receptor activity 2.76876397305497 bayes_pls_golite062009
cytokine receptor binding 2.64284554734326 bayes_pls_golite062009
ciliary neurotrophic factor binding 2.27923575030525 bayes_pls_golite062009
transcription regulator activity 2.25224014924603 bayes_pls_golite062009
growth hormone receptor activity 2.20449493522 bayes_pls_golite062009
nucleic acid binding 2.13821456373219 bayes_pls_golite062009
peptide binding 2.04467673245315 bayes_pls_golite062009
DNA binding 1.95396591505956 bayes_pls_golite062009
peptide hormone binding 1.9205359237864 bayes_pls_golite062009
phosphoinositide 3-kinase binding 1.91712452737778 bayes_pls_golite062009
transcription activator activity 1.72598380808039 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.61421027298524 bayes_pls_golite062009
kinase activity 1.57994485110649 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.44501485815273 bayes_pls_golite062009
protein kinase activity 1.42856560840953 bayes_pls_golite062009
insulin binding 1.40490582483684 bayes_pls_golite062009
receptor binding 1.31676259534833 bayes_pls_golite062009
hormone binding 1.31120662451488 bayes_pls_golite062009
interleukin-11 receptor activity 1.2674474182257 bayes_pls_golite062009
interleukin-11 binding 1.2674474182257 bayes_pls_golite062009
transcription factor activity 1.20939978283833 bayes_pls_golite062009
transferase activity 1.13635878582843 bayes_pls_golite062009
protein dimerization activity 0.86564366658585 bayes_pls_golite062009
protein serine/threonine kinase activity 0.703490254739121 bayes_pls_golite062009
axon guidance receptor activity 0.664115701581569 bayes_pls_golite062009
kinase binding 0.65927255037265 bayes_pls_golite062009
enzyme binding 0.60195860585095 bayes_pls_golite062009
identical protein binding 0.564711394496051 bayes_pls_golite062009
transmembrane receptor protein tyrosine kinase activity 0.554350228628563 bayes_pls_golite062009
mercury ion binding 0.533389420538679 bayes_pls_golite062009
transmembrane receptor protein kinase activity 0.46168925186147 bayes_pls_golite062009
transcription factor binding 0.428445565158989 bayes_pls_golite062009
protein kinase binding 0.405060010394646 bayes_pls_golite062009
cytokine activity 0.30745438910441 bayes_pls_golite062009
peptidase activator activity 0.249363133780499 bayes_pls_golite062009
interleukin-2 binding 0.240383688164201 bayes_pls_golite062009
prolactin receptor activity 0.227864369774704 bayes_pls_golite062009
transcription cofactor activity 0.211855991357483 bayes_pls_golite062009
structural molecule activity 0.18965275490219 bayes_pls_golite062009
protein heterodimerization activity 0.1430595594485 bayes_pls_golite062009
protein homodimerization activity 0.116391819218123 bayes_pls_golite062009
cytoskeletal protein binding 0.116377273702831 bayes_pls_golite062009
transcription coactivator activity 0.05634414824449 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [456-664] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSANESLEVM DELEVEPHSV LLQDVLGEGA FGLVRRGVYK KRQVAVKLLK DEPNDEDVYA  60
   61 FKCEIQMLKA VGKHPNIVGI VGYSTRFSNQ MMLLIEYCSL GSLQNFLREE WKFRQEQNAI 120
  121 GLKKNLEQNV DNRRFNRLPR NSIHDRIEDI NNSMLSTVEE ESESDQTHSS RCETYTLTRI 180
  181 TNAADNKGYG LEDIENIGGS YIPKTAEAP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 6.7
Match: 2nruA
Description: No description for 2nruA was found.

Predicted Domain #4
Region A:
Residues: [665-923] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDRPKRKLKP QPKKDSKQDF KSDNKKRIFE NKEYFDCLDS SDTKPRIPLK YADLLDIAQQ  60
   61 VAVGMEFLAQ NKVVHRDLAA RNVLISVDRS IKIADFGLSR DVYHENVYRK SGGSGKLPIK 120
  121 WLALESLTHQ VYTSQSDVWS FGVLLYEITT LGGMPYPSVS PSDLLQLLRQ GHRMKRPEGC 180
  181 TQEMFSLMES CWSSVPSHRP TFSALKHRLG GMILATNDVP ERLKQLQAAT ESKLKSCDGL 240
  241 NSKVEQVPCE EELYLEPLN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.0
Match: 2pvfA
Description: No description for 2pvfA was found.
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle