YRC Public Data Repository - Protein Structure Prediction

Protein:	NTE1_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	1316 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NTE1_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|46121839, gi\|... - gi\|46121839\|ref\|XP_385473.1\| hypothetical protein FG05297.1 [Gibberella zeae PH-1], gi\|42552690\|gb\|E...	1067.0	[0..1]	[1316..33]
NTE1_MAGGR - Lysophospholipase NTE1 OS=Magnaporthe grisea GN=NTE1 PE=3 SV=2 NTE1_MAGO7 - Lysophospholipase NTE1 OS=Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) GN=NTE1 PE=3...	1040.0	[0..5]	[1316..16]
gi\|159122289 - gi\|159122289\|gb\|EDP47411.1\| Patatin-like serine hydrolase, putative [Aspergillus fumigatus A1163] NTE1_ASPFU - Lysophospholipase nte1 OS=Aspergillus fumigatus GN=nte1 PE=3 SV=1 NTE1_ASPFU - Lysophospholipase nte1 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A11...	1006.0	[0..20]	[1316..65]
NTE1_ASPTN - Lysophospholipase nte1 OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) GN=nte1 PE=3 SV=1	1000.0	[0..20]	[1316..69]
gi\|40744643, gi\|... - gi\|67524047\|ref\|XP_660085.1\| hypothetical protein AN2481.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	986.0	[0..66]	[1316..2]
NTE1_PHANO - Lysophospholipase NTE1 OS=Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) GN=NTE1 P... NTE1_PHANO - Lysophospholipase NTE1 OS=Phaeosphaeria nodorum GN=NTE1 PE=3 SV=1	977.0	[0..8]	[1316..35]
NTE1_CANAL - Lysophospholipase NTE1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NTE1 PE=3 SV=1 NTE1_CANAL - Lysophospholipase NTE1 OS=Candida albicans GN=NTE1 PE=3 SV=1	939.0	[0..2]	[1295..4]
NTE1_ASHGO - Lysophospholipase NTE1 OS=Ashbya gossypii GN=NTE1 PE=3 SV=1 NTE1_ASHGO - Lysophospholipase NTE1 OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)...	922.0	[0..34]	[1316..49]
gi\|88180676, gi\|... - gi\|88180676\|gb\|EAQ88144.1\| hypothetical protein CHGG_04763 [Chaetomium globosum CBS 148.51], gi\|1161...	910.0	[0..10]	[1316..46]
gi\|19343904 - gi\|19343904\|gb\|AAH25621.1\| Pnpla7 protein [Mus musculus]	902.0	[0..78]	[1306..3]

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Predicted Domain #1

Region A:
Residues: [1-92]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDITDRILQN RIVSKVIFFV LRSVTLSLVS VTRFSLFLLS FATITVPKWA YKIVTYSLTI  60
   61 QFNFKSLLFL FFVSICVVIL VVRYRYLNKY AR

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [93-338]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPHEAPIKEA KLGPDTNIRP SEPRIGFQNY LDEFLSAISI FGYLEKPVFV ELARHIRTQR  60
   61 VAEGNTIYLG EQSSFILVVD GCFQVFTAPE KDSAEVVEEA GQPEYRLLTE VSNGAPLSSF 120
  121 FTVLELFTEL IPEATSKENP FKSTTSSLRP GSSTTTEAGA NNASKPHMPQ PKKARIIAKA 180
  181 KIDTTIAVIP ANAFHHLVHK FPNSSAQIVQ VILTRFQRVT FSTGYEYLGL SDAIFSIEKN 240
  241 FNSLTA

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.31
Match:	2pqqA
Description:	No description for 2pqqA was found.

Predicted Domain #3

Region A:
Residues: [339-454]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YELPNYIRSD IIDDFKKEAM SEHLSQASNE SFIVLRSKGA QSRLSNQYFS KAFDKEHGNF  60
   61 VSDIDRSTAN AGDLLSSTNP HSTLLSTSVG PLRKFPLNRS YSREVGDYDI SASFRD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [455-774]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLLQCIFKSL GVFNYELKED NDDLCTENDS SEGDSDSLKK VDFLGQIAMM SATDREEVKS  60
   61 SIVVSTKKST ILEFAKEIEI IFYKKGTTIV RQGDHADGLY YIIDGFLDAT CPSKLTFSTS 120
  121 YDTDLGMHSF MIKPGGIVNY QACVSNYRSF INVTARSDVL VGFLPRSCLE RIIDQEPLIS 180
  181 LTIAKRLISL VPSLLLKLDF AVGWIHLNPD QVVYEKNDPS DCVYVVLNGR LRSIEDERGS 240
  241 ARTQVDYFNE YGKGDSVGEL EMLLNNRRSS TLFAIRDSEL AKIPETLFNA LSLSHPAVGL 300
  301 QLSKIIANRM NLLLNNKSMD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.69897
Match:	1ne4A
Description:	Crystal Structure of Rp-cAMP Binding R1a Subunit of cAMP-dependent Protein Kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ion channel activity	0.520384303065647	bayes_pls_golite062009
ligand-gated ion channel activity	0.497828140064889	bayes_pls_golite062009
ligand-gated channel activity	0.497828140064889	bayes_pls_golite062009
substrate-specific channel activity	0.48319462308643	bayes_pls_golite062009
channel activity	0.454459555295387	bayes_pls_golite062009
passive transmembrane transporter activity	0.454459555295387	bayes_pls_golite062009
gated channel activity	0.409785236987708	bayes_pls_golite062009
ion transmembrane transporter activity	0.341708851952942	bayes_pls_golite062009
cation channel activity	0.341210684071064	bayes_pls_golite062009
cation transmembrane transporter activity	0.105498264304027	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.0334592868738468	bayes_pls_golite062009

Predicted Domain #5

Region A:
Residues: [775-843]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GMQHQPHEKH SIRTLAIVPS SSTGLLILFS QKLTSVLSVM GKSVKVLRQS SVLEHLGKHA  60
   61 FSRMGRFKL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.30103
Match:	1i5zA
Description:	Catabolite gene activator protein (CAP), C-terminal domain; Catabolite gene activator protein, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	2.19662303952524	bayes_pls_golite062009
nucleic acid binding	2.17489737456358	bayes_pls_golite062009
DNA binding	2.1344026805098	bayes_pls_golite062009
transcription factor activity	1.45035959828954	bayes_pls_golite062009
binding	0.554619018401844	bayes_pls_golite062009
sequence-specific DNA binding	0.279998232866747	bayes_pls_golite062009
transcription activator activity	0.078739212646842	bayes_pls_golite062009

Predicted Domain #6

Region A:
Residues: [844-1005]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSYLSDLEDK YDILIYVADS GVGSAWLQTC IRQADCIYIL AEADQNPNIG EYEQHLIAMK  60
   61 STARKELVLL HPERFCPSGL TRLWLKERPW VYAHHHVQLR IGLDNEISQN NEAKVFLNII 120
  121 RAKVQNLHYG FRKYIDWKHL HPVYQANRAQ DSDFARLARR IC

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.839	c.13.2	Anti-sigma factor antagonist SpoIIaa

Predicted Domain #7

Region A:
Residues: [1006-1316]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKAIALVLGG GGARGISQIG ILYALEEAGI PFDIIGGTSI GAFNGGLYAW EADLVPMFGR  60
   61 AKKFCGRMAN LWRFVLDVTY PQAAYTTGHE FNRGIWKTFG EIHIEDFWLP FYANTTNITH 120
  121 SRMDIHSSGY AWRYIRASMS LAGLVPPMLS DSGDMLLDGG YMDNLTVSHM QSLGASSIFA 180
  181 IDVGSEDSRE PMHYGDTVSG VWALISRWIP FIPKTSFPSL AEIQSRLTYV TSVATGEKVK 240
  241 SMPGCFYMRP PVKDFPTLEF GSFEKIYNVG YNYGKEYVEK LKTSHKLDDI LSPRDTSKRH 300
  301 PKFLSSRRNS L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	37.522879
Match:	1oxwA
Description:	Patatin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phospholipase activity	3.87963112297417	bayes_pls_golite062009
phospholipase A2 activity	3.8689576466535	bayes_pls_golite062009
lipase activity	1.83391969295473	bayes_pls_golite062009
catalytic activity	1.681309422157	bayes_pls_golite062009
calcium-independent phospholipase A2 activity	1.65363998249183	bayes_pls_golite062009
fatty acid synthase activity	1.20394174397151	bayes_pls_golite062009
S-acyltransferase activity	1.07865077162953	bayes_pls_golite062009
hydrolase activity	0.949372513160363	bayes_pls_golite062009
[acyl-carrier-protein] S-malonyltransferase activity	0.812816692540436	bayes_pls_golite062009
S-malonyltransferase activity	0.812816692540436	bayes_pls_golite062009
malonyltransferase activity	0.812816692540436	bayes_pls_golite062009
carboxylesterase activity	0.431665185524913	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.39017969987234	bayes_pls_golite062009
acyltransferase activity	0.350701756346828	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	0.295883900540457	bayes_pls_golite062009
phospholipid binding	0.04135826589249	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions:

Predicted functions: