| Protein: | Dscam-PJ |
| Organism: | Drosophila melanogaster |
| Length: | 2016 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Dscam-PJ.
| Description | E-value | Query Range |
Subject Range |
|
|
1543.0 | [0..3] | [2016..3] |
|
Region A: Residues: [1-143] |
1 11 21 31 41 51
| | | | | |
1 MNMPNERLKW LMLFAAVALI ACGSQTLAAN PPDADQKGPV FLKEPTNRID FSNSTGAEIE 60
61 CKASGNPMPE IIWIRSDGTA VGDVPGLRQI SSDGKLVFPP FRAEDYRQEV HAQVYACLAR 120
121 NQFGSIISRD VHVRAVVAQY YEA
|
| Detection Method: |  |
| Confidence: | 81.0 |
| Match: | 2v5sA |
| Description: | No description for 2v5sA was found. |
|
Region A: Residues: [144-264] |
1 11 21 31 41 51
| | | | | |
1 DVNKEHVIRG NSAVIKCLIP SFVADFVEVV SWHTDEEENY FPGAEYDGKY LVLPSGELHI 60
61 REVGPEDGYK SYQCRTKHRL TGETRLSATK GRLVITEPIG ARAPTFSTDS IVFSYIRPVG 120
121 Q
|
| Detection Method: | |
| Confidence: | 8.522879 |
| Match: | 1igyB |
| Description: | Immunoglobulin heavy chain variable domain, VH; Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma; Immunoglobulin heavy chain gamma constant domain 2, CH2-gamma; Immunoglobulin heavy chain gamma constant domain 3, CH3-gamma |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telethonin binding | 6.64811984458494 | bayes_pls_golite062009 |
| alpha-actinin binding | 5.77350124471385 | bayes_pls_golite062009 |
| actinin binding | 5.69539760434923 | bayes_pls_golite062009 |
| structural constituent of muscle | 4.93896503565413 | bayes_pls_golite062009 |
| olfactory receptor activity | 4.21057154107121 | bayes_pls_golite062009 |
| antigen binding | 4.06466268219034 | bayes_pls_golite062009 |
| binding | 3.17641566810715 | bayes_pls_golite062009 |
| receptor activity | 3.0754311615326 | bayes_pls_golite062009 |
| peptide antigen binding | 2.94721224577771 | bayes_pls_golite062009 |
| molecular transducer activity | 2.92683710723714 | bayes_pls_golite062009 |
| signal transducer activity | 2.92683710723714 | bayes_pls_golite062009 |
| fibroblast growth factor 1 binding | 2.83860944503193 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.79758224858792 | bayes_pls_golite062009 |
| protein binding | 2.22855404705168 | bayes_pls_golite062009 |
| IgG binding | 1.92633562075074 | bayes_pls_golite062009 |
| receptor binding | 1.70260377709721 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.58610597245454 | bayes_pls_golite062009 |
| actin binding | 1.42681407553255 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 1.36789541796983 | bayes_pls_golite062009 |
| protein kinase activity | 1.36635494500222 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32330470851159 | bayes_pls_golite062009 |
| fibroblast growth factor binding | 1.27793818082552 | bayes_pls_golite062009 |
| DNA binding | 1.19412627500732 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.17845072849922 | bayes_pls_golite062009 |
| transcription regulator activity | 1.16252234499274 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.02286631988334 | bayes_pls_golite062009 |
| kinase activity | 0.929878054374821 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.878595022643164 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 0.84475532395276 | bayes_pls_golite062009 |
| actin filament binding | 0.760856470721016 | bayes_pls_golite062009 |
| growth factor binding | 0.715053526402219 | bayes_pls_golite062009 |
| collagen binding | 0.635057461053063 | bayes_pls_golite062009 |
| titin binding | 0.599892148302011 | bayes_pls_golite062009 |
| integrin binding | 0.599569390248921 | bayes_pls_golite062009 |
| structural molecule activity | 0.567620977360967 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.564762108830441 | bayes_pls_golite062009 |
| transcription factor activity | 0.54549168007511 | bayes_pls_golite062009 |
| myosin heavy chain binding | 0.49788128784685 | bayes_pls_golite062009 |
| protein complex binding | 0.43131084085213 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 0.318890055375093 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.0579247757286607 | bayes_pls_golite062009 |
|
Region A: Residues: [265-720] |
1 11 21 31 41 51
| | | | | |
1 SFALLCQAQA YPVPAMRWYK FIEGTTRKQA VVLNDRVKQV SGTLIIKDAV VEDSGKYLCV 60
61 VNNSVGGESV ETVLTVTAPL SAKIDPPTQT VDFGRPAVFT CQYTGNPIKT VSWMKDGKAI 120
121 GHSEPVLRIE SVKKEDKGMY QCFVRNDQES AEASAELKLG GRFDPPVIRQ AFQEETMEPG 180
181 PSVFLKCVAG GNPTPEISWE LDGKKIANND RYQVGQYVTV NGDVVSYLNI TSVHANDGGL 240
241 YKCIAKSKVG VAEHSAKLNV YGLPYIRQME KKAIVAGETL IVTCPVAGYP IDSIVWERDN 300
301 RALPINRKQK VFPNGTLIIE NVERNSDQAT YTCVAKNQEG YSARGSLEVQ VMVPPKITPF 360
361 DFGDEPTNFE DSVSVTCLIS SGDLPIDIEW FFNEYGISSY SGISVVKGGK RNSVLSIDSV 420
421 QARHAGNYSC RAKNHAAAVN YTTSLIVNVP PRWILE
|
| Detection Method: | |
| Confidence: | 55.0 |
| Match: | 1e07A |
| Description: | Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [721-1375] |
1 11 21 31 41 51
| | | | | |
1 PTDKAFAQGS DAKVECKADG FPKPQVTWKK AVGDTPGEYK DLKKSDNIRV EEGTLHVDNI 60
61 QKTNEGYYLC EAINGIGSGL SAVIMISVQA PPEFTEKLRN QTARRGEPAV LQCEAKGEKP 120
121 IGILWNMNNM RLDPKNDNRY TIREEILSTG VMSSLSIKRT ERSDSALFTC VATNAFGSDD 180
181 ASINMIVQEV PEMPYALKVL DKSGRSVQLS WAQPYDGNSP LDRYIIEFKR SRASWSEIDR 240
241 VIVPGHTTEA QVQKLSPATT YNIRIVAENA IGTSQSSEAV TIITAEEAPS GKPQNIKVEP 300
301 VNQTTMRVTW KPPPRTEWNG EILGYYVGYK LSNTNSSYVF ETINFITEEG KEHNLELQNL 360
361 RVYTQYSVVI QAFNKIGAGP LSEEEKQFTA EGTPSQPPSD TACTTLTSQT IRVGWVSPPL 420
421 ESANGVIKTY KVVYAPSDEW YDETKRHYKK TASSDTVLHG LKKYTNYTMQ VLATTAGGDG 480
481 VRSVPIHCQT EPDVPEAPTD VKALVMGNAA ILVSWRPPAQ PNGIITQYTV YSKAEGAETE 540
541 TKTQKVPHYQ MSFEATELEK NKPYEFWVTA STTIGEGQQS KSIVAMPSDQ VPAKIASFDD 600
601 TFTATFKEDA KMPCLAVGAP QPEITWKIKG VEFSANDRMR VLPDGSLLIK SVNRQ
|
| Detection Method: | |
| Confidence: | 29.39794 |
| Match: | 2v5yA |
| Description: | No description for 2v5yA was found. |
|
Region A: Residues: [1376-1602] |
1 11 21 31 41 51
| | | | | |
1 DAGDYSCHAE NSIAKDSITH KLIVLAPPQS PHVTLSATTT DALTVKLKPH EGDTAPLHGY 60
61 TLHYKPEFGE WETSEVSVDS QKHNIEGLLC GSRYQVYATG FNNIGAGEAS DILNTRTKGQ 120
121 KPKLPEKPRF IEVSSNSVSL HFKAWKDGGC PMSHFVVESK KRDQIEWNQI SNNVKPDNNY 180
181 VVLDLEPATW YNLRITAHNS AGFTVAEYDF ATLTVTGGTI APSRDLP
|
| Detection Method: | |
| Confidence: | 21.69897 |
| Match: | 1fnhA |
| Description: | Fibronectin, different Fn3 modules |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telethonin binding | 5.81747667416248 | bayes_pls_golite062009 |
| structural constituent of muscle | 5.71979489668015 | bayes_pls_golite062009 |
| ankyrin binding | 4.69755754047169 | bayes_pls_golite062009 |
| alpha-actinin binding | 4.57951951779666 | bayes_pls_golite062009 |
| actinin binding | 4.57900103206288 | bayes_pls_golite062009 |
| transmembrane receptor activity | 3.79244614134061 | bayes_pls_golite062009 |
| receptor activity | 3.73567137429359 | bayes_pls_golite062009 |
| cytokine binding | 3.58426984827737 | bayes_pls_golite062009 |
| molecular transducer activity | 3.5100441341515 | bayes_pls_golite062009 |
| signal transducer activity | 3.5100441341515 | bayes_pls_golite062009 |
| cytokine receptor activity | 3.25206686803048 | bayes_pls_golite062009 |
| protein binding | 3.24522318184038 | bayes_pls_golite062009 |
| binding | 3.12471204223368 | bayes_pls_golite062009 |
| growth factor binding | 2.4970104838834 | bayes_pls_golite062009 |
| receptor binding | 2.38673889309915 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 2.32179186005318 | bayes_pls_golite062009 |
| axon guidance receptor activity | 2.01367445237355 | bayes_pls_golite062009 |
| prolactin receptor activity | 1.9556649101819 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.85720106085239 | bayes_pls_golite062009 |
| interleukin-2 binding | 1.67132604890013 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 1.56410665522466 | bayes_pls_golite062009 |
| interleukin-6 binding | 1.53073516901486 | bayes_pls_golite062009 |
| interleukin-6 receptor activity | 1.53073516901486 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.49217960276915 | bayes_pls_golite062009 |
| mercury ion binding | 1.46191698606762 | bayes_pls_golite062009 |
| protein kinase activity | 1.42856560840953 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32813363771214 | bayes_pls_golite062009 |
| transcription regulator activity | 1.31663344632755 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor activity | 1.27192437373177 | bayes_pls_golite062009 |
| peptide hormone binding | 1.2420090521345 | bayes_pls_golite062009 |
| actin binding | 1.21472460452555 | bayes_pls_golite062009 |
| DNA binding | 1.2006039770643 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.15899955607967 | bayes_pls_golite062009 |
| heparin binding | 1.15000556789505 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.12142142875217 | bayes_pls_golite062009 |
| kinase activity | 1.11027658115625 | bayes_pls_golite062009 |
| extracellular matrix structural constituent | 1.1057194345531 | bayes_pls_golite062009 |
| cytokine activity | 1.09433218752101 | bayes_pls_golite062009 |
| structural molecule activity | 0.94240190391222 | bayes_pls_golite062009 |
| protein dimerization activity | 0.86564366658585 | bayes_pls_golite062009 |
| growth hormone receptor activity | 0.840187286074179 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.703490254739121 | bayes_pls_golite062009 |
| kinase binding | 0.65927255037265 | bayes_pls_golite062009 |
| leukemia inhibitory factor receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| oncostatin-M receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| enzyme binding | 0.60195860585095 | bayes_pls_golite062009 |
| collagen binding | 0.593745877718282 | bayes_pls_golite062009 |
| identical protein binding | 0.564711394496051 | bayes_pls_golite062009 |
| transcription factor activity | 0.557290274937694 | bayes_pls_golite062009 |
| polysaccharide binding | 0.54737137289904 | bayes_pls_golite062009 |
| cytokine receptor binding | 0.47107517390107 | bayes_pls_golite062009 |
| pattern binding | 0.44460010885883 | bayes_pls_golite062009 |
| growth factor activity | 0.432629984792427 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.40600177052491 | bayes_pls_golite062009 |
| protein kinase binding | 0.405060010394646 | bayes_pls_golite062009 |
| cell surface binding | 0.366415248711076 | bayes_pls_golite062009 |
| interleukin-7 binding | 0.301052531308189 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.1430595594485 | bayes_pls_golite062009 |
| transcription activator activity | 0.135753557343301 | bayes_pls_golite062009 |
| actin filament binding | 0.135484838710405 | bayes_pls_golite062009 |
| protease binding | 0.12595904253108 | bayes_pls_golite062009 |
| protein homodimerization activity | 0.116391819218123 | bayes_pls_golite062009 |
| interleukin-2 receptor activity | 0.115337814289139 | bayes_pls_golite062009 |
| integrin binding | 0.0873424694168858 | bayes_pls_golite062009 |
| transcription factor binding | 0.075900818564989 | bayes_pls_golite062009 |
| interleukin-11 binding | 0.0423783987133706 | bayes_pls_golite062009 |
| interleukin-11 receptor activity | 0.0423783987133706 | bayes_pls_golite062009 |
|
Region A: Residues: [1603-1680] |
1 11 21 31 41 51
| | | | | |
1 ELSAEDTIRI ILSNLNLVVP VVAALLVIII AIIVICILRS KGNHHKDDVV YNQTMGPGAT 60
61 LDKRRPDLRD ELGYIAPP
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1681-1922] |
1 11 21 31 41 51
| | | | | |
1 NRKLPPVPGS NYNTCDRIKR GRGGLRSNHS TWDPRRNPNL YEELKAPPVP MHGNHYGHAH 60
61 GNAECHYRHP GMEDEICPYA TFHLLGFREE MDPTKAMNFQ TFPHQNGHAG PVPGHAGTML 120
121 PPGHPGHVHS RSGSQSMPRA NRYQRKNSQG GQSSIYTPAP EYDDPANCAE EDQYRRYTRV 180
181 NSQGGSLYSG PGPEYDDPAN CAPEEDQYGS QYGGPYGQPY DHYGSRGSMG RRSIGSARNP 240
241 GN
|
| Detection Method: | |
| Confidence: | 10.30103 |
| Match: | 2nv5A |
| Description: | No description for 2nv5A was found. |
|
Region A: Residues: [1923-2016] |
1 11 21 31 41 51
| | | | | |
1 GSPEPPPPPP RNHDMSNSSF NDSKESNEIS EAECDRDHGP RGNYGAVKRS PQPKDQRTTE 60
61 EMRKLIERNE TGPKQLQLQQ ANGAGFTAYD TMAV
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
