| Protein: | Dscam-PI |
| Organism: | Drosophila melanogaster |
| Length: | 2017 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Dscam-PI.
| Description | E-value | Query Range |
Subject Range |
|
|
1524.0 | [0..3] | [2017..3] |
|
Region A: Residues: [1-153] |
1 11 21 31 41 51
| | | | | |
1 MNMPNERLKW LMLFAAVALI ACGSQTLAAN PPDADQKGPV FLKEPTNRID FSNSTGAEIE 60
61 CKASGNPMPE IIWIRSDGTA VGDVPGLRQI SSDGKLVFPP FRAEDYRQEV HAQVYACLAR 120
121 NQFGSIISRD VHVRAVVAQY YEADVNKEHV IRG
|
| Detection Method: |  |
| Confidence: | 83.0 |
| Match: | 2v5sA |
| Description: | No description for 2v5sA was found. |
|
Region A: Residues: [154-243] |
1 11 21 31 41 51
| | | | | |
1 NSAVIKCLIP SFVADFVEVV SWHTDEEENY FPGAEYDGKY LVLPSGELHI REVGPEDGYK 60
61 SYQCRTKHRL TGETRLSATK GRLVITEPVG
|
| Detection Method: | |
| Confidence: | 7.39794 |
| Match: | 1igtB |
| Description: | Immunoglobulin heavy chain variable domain, VH; Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma; Immunoglobulin heavy chain gamma constant domain 2, CH2-gamma; Immunoglobulin heavy chain gamma constant domain 3, CH3-gamma |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telethonin binding | 6.64811984458494 | bayes_pls_golite062009 |
| alpha-actinin binding | 5.77350124471385 | bayes_pls_golite062009 |
| actinin binding | 5.69539760434923 | bayes_pls_golite062009 |
| structural constituent of muscle | 4.93896503565413 | bayes_pls_golite062009 |
| olfactory receptor activity | 4.21057154107121 | bayes_pls_golite062009 |
| antigen binding | 4.06466268219034 | bayes_pls_golite062009 |
| binding | 3.17641566810715 | bayes_pls_golite062009 |
| receptor activity | 3.0754311615326 | bayes_pls_golite062009 |
| peptide antigen binding | 2.94721224577771 | bayes_pls_golite062009 |
| molecular transducer activity | 2.92683710723714 | bayes_pls_golite062009 |
| signal transducer activity | 2.92683710723714 | bayes_pls_golite062009 |
| fibroblast growth factor 1 binding | 2.83860944503193 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.79758224858792 | bayes_pls_golite062009 |
| protein binding | 2.22855404705168 | bayes_pls_golite062009 |
| IgG binding | 1.92633562075074 | bayes_pls_golite062009 |
| receptor binding | 1.70260377709721 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.58610597245454 | bayes_pls_golite062009 |
| actin binding | 1.42681407553255 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 1.36789541796983 | bayes_pls_golite062009 |
| protein kinase activity | 1.36635494500222 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32330470851159 | bayes_pls_golite062009 |
| fibroblast growth factor binding | 1.27793818082552 | bayes_pls_golite062009 |
| DNA binding | 1.19412627500732 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.17845072849922 | bayes_pls_golite062009 |
| transcription regulator activity | 1.16252234499274 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.02286631988334 | bayes_pls_golite062009 |
| kinase activity | 0.929878054374821 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.878595022643164 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 0.84475532395276 | bayes_pls_golite062009 |
| actin filament binding | 0.760856470721016 | bayes_pls_golite062009 |
| growth factor binding | 0.715053526402219 | bayes_pls_golite062009 |
| collagen binding | 0.635057461053063 | bayes_pls_golite062009 |
| titin binding | 0.599892148302011 | bayes_pls_golite062009 |
| integrin binding | 0.599569390248921 | bayes_pls_golite062009 |
| structural molecule activity | 0.567620977360967 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.564762108830441 | bayes_pls_golite062009 |
| transcription factor activity | 0.54549168007511 | bayes_pls_golite062009 |
| myosin heavy chain binding | 0.49788128784685 | bayes_pls_golite062009 |
| protein complex binding | 0.43131084085213 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 0.318890055375093 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.0579247757286607 | bayes_pls_golite062009 |
|
Region A: Residues: [244-896] |
1 11 21 31 41 51
| | | | | |
1 GKAPTLLSND IKRSWIERML STNLALFCPA QGFPVPAFRW YKFIEGTTRK QAVVLNDRVK 60
61 QVSGTLIIKD AVVEDSGKYL CVVNNSVGGE SVETVLTVTA PLSAKIDPPT QTVDFGRPAV 120
121 FTCQYTGNPI KTVSWMKDGK AIGHSEPVLR IESVKKEDKG MYQCFVRNDQ ESAEASAELK 180
181 LGGRFDPPVI RQAFQEETME PGPSVFLKCV AGGNPTPEIS WELDGKKIAN NDRYQVGQYV 240
241 TVNGDVVSYL NITSVHANDG GLYKCIAKSK VGVAEHSAKL NVYGLPYIRQ MEKKAIVAGE 300
301 TLIVTCPVAG YPIDSIVWER DNRALPINRK QKVFPNGTLI IENVERNSDQ ATYTCVAKNQ 360
361 EGYSARGSLE VQVMVPPKIT PFDFGDEPTN FEDSVSVTCL ISSGDLPIDI EWFFNEYGIS 420
421 SYSGISVVKG GKRNSVLSID SVQARHAGNY SCRAKNHAAA VNYTTSLIVN VPPRWILEPT 480
481 DKAFAQGSDA KVECKADGFP KPQVTWKKAV GDTPGEYKDL KKSDNIRVEE GTLHVDNIQK 540
541 TNEGYYLCEA INGIGSGLSA VIMISVQAPP EFTEKLRNQT ARRGEPAVLQ CEAKGEKPIG 600
601 ILWNMNNMRL DPKNDNRYTI REEILSTGVM SSLSIKRTER SDSALFTCVA TNA
|
| Detection Method: | |
| Confidence: | 58.045757 |
| Match: | 1e07A |
| Description: | Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [897-1009] |
1 11 21 31 41 51
| | | | | |
1 FGSDDASINM IVQEVPEMPY ALKVLDKSGR SVQLSWAQPY DGNSPLDRYI IEFKRSRASW 60
61 SEIDRVIVPG HTTEAQVQKL SPATTYNIRI VAENAIGTSQ SSEAVTIITA EEA
|
| Detection Method: | |
| Confidence: | 37.522879 |
| Match: | 2nziA |
| Description: | No description for 2nziA was found. |
|
Region A: Residues: [1010-1112] |
1 11 21 31 41 51
| | | | | |
1 PSGKPQNIKV EPVNQTTMRV TWKPPPRTEW NGEILGYYVG YKLSNTNSSY VFETINFITE 60
61 EGKEHNLELQ NLRVYTQYSV VIQAFNKIGA GPLSEEEKQF TAE
|
| Detection Method: | |
| Confidence: | 10.69897 |
| Match: | 1va9A |
| Description: | Solution structure of the second FNIII domain of DSCAML1 protein |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telethonin binding | 5.81747667416248 | bayes_pls_golite062009 |
| structural constituent of muscle | 5.71979489668015 | bayes_pls_golite062009 |
| ankyrin binding | 4.69755754047169 | bayes_pls_golite062009 |
| alpha-actinin binding | 4.57951951779666 | bayes_pls_golite062009 |
| actinin binding | 4.57900103206288 | bayes_pls_golite062009 |
| transmembrane receptor activity | 3.79244614134061 | bayes_pls_golite062009 |
| receptor activity | 3.73567137429359 | bayes_pls_golite062009 |
| cytokine binding | 3.58426984827737 | bayes_pls_golite062009 |
| molecular transducer activity | 3.5100441341515 | bayes_pls_golite062009 |
| signal transducer activity | 3.5100441341515 | bayes_pls_golite062009 |
| cytokine receptor activity | 3.25206686803048 | bayes_pls_golite062009 |
| protein binding | 3.24522318184038 | bayes_pls_golite062009 |
| binding | 3.12471204223368 | bayes_pls_golite062009 |
| growth factor binding | 2.4970104838834 | bayes_pls_golite062009 |
| receptor binding | 2.38673889309915 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 2.32179186005318 | bayes_pls_golite062009 |
| axon guidance receptor activity | 2.01367445237355 | bayes_pls_golite062009 |
| prolactin receptor activity | 1.9556649101819 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.85720106085239 | bayes_pls_golite062009 |
| interleukin-2 binding | 1.67132604890013 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 1.56410665522466 | bayes_pls_golite062009 |
| interleukin-6 binding | 1.53073516901486 | bayes_pls_golite062009 |
| interleukin-6 receptor activity | 1.53073516901486 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.49217960276915 | bayes_pls_golite062009 |
| mercury ion binding | 1.46191698606762 | bayes_pls_golite062009 |
| protein kinase activity | 1.42856560840953 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32813363771214 | bayes_pls_golite062009 |
| transcription regulator activity | 1.31663344632755 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor activity | 1.27192437373177 | bayes_pls_golite062009 |
| peptide hormone binding | 1.2420090521345 | bayes_pls_golite062009 |
| actin binding | 1.21472460452555 | bayes_pls_golite062009 |
| DNA binding | 1.2006039770643 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.15899955607967 | bayes_pls_golite062009 |
| heparin binding | 1.15000556789505 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.12142142875217 | bayes_pls_golite062009 |
| kinase activity | 1.11027658115625 | bayes_pls_golite062009 |
| extracellular matrix structural constituent | 1.1057194345531 | bayes_pls_golite062009 |
| cytokine activity | 1.09433218752101 | bayes_pls_golite062009 |
| structural molecule activity | 0.94240190391222 | bayes_pls_golite062009 |
| protein dimerization activity | 0.86564366658585 | bayes_pls_golite062009 |
| growth hormone receptor activity | 0.840187286074179 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.703490254739121 | bayes_pls_golite062009 |
| kinase binding | 0.65927255037265 | bayes_pls_golite062009 |
| leukemia inhibitory factor receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| oncostatin-M receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| enzyme binding | 0.60195860585095 | bayes_pls_golite062009 |
| collagen binding | 0.593745877718282 | bayes_pls_golite062009 |
| identical protein binding | 0.564711394496051 | bayes_pls_golite062009 |
| transcription factor activity | 0.557290274937694 | bayes_pls_golite062009 |
| polysaccharide binding | 0.54737137289904 | bayes_pls_golite062009 |
| cytokine receptor binding | 0.47107517390107 | bayes_pls_golite062009 |
| pattern binding | 0.44460010885883 | bayes_pls_golite062009 |
| growth factor activity | 0.432629984792427 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.40600177052491 | bayes_pls_golite062009 |
| protein kinase binding | 0.405060010394646 | bayes_pls_golite062009 |
| cell surface binding | 0.366415248711076 | bayes_pls_golite062009 |
| interleukin-7 binding | 0.301052531308189 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.1430595594485 | bayes_pls_golite062009 |
| transcription activator activity | 0.135753557343301 | bayes_pls_golite062009 |
| actin filament binding | 0.135484838710405 | bayes_pls_golite062009 |
| protease binding | 0.12595904253108 | bayes_pls_golite062009 |
| protein homodimerization activity | 0.116391819218123 | bayes_pls_golite062009 |
| interleukin-2 receptor activity | 0.115337814289139 | bayes_pls_golite062009 |
| integrin binding | 0.0873424694168858 | bayes_pls_golite062009 |
| transcription factor binding | 0.075900818564989 | bayes_pls_golite062009 |
| interleukin-11 binding | 0.0423783987133706 | bayes_pls_golite062009 |
| interleukin-11 receptor activity | 0.0423783987133706 | bayes_pls_golite062009 |
|
Region A: Residues: [1113-1158] |
1 11 21 31 41 51
| | | | | |
1 GTPSQPPSDT ACTTLTSQTI RVGWVSPPLE SANGVIKTYK VVYAPS
|
| Detection Method: | |
| Confidence: | 12.09691 |
| Match: | 1x5hA |
| Description: | The solution structure of the third fibronectin type III domain of human Neogenin |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1159-1605] |
1 11 21 31 41 51
| | | | | |
1 DEWYDETKRH YKKTASSDTV LHGLKKYTNY TMQVLATTAG GDGVRSVPIH CQTEPDVPEA 60
61 PTDVKALVMG NAAILVSWRP PAQPNGIITQ YTVYSKAEGA ETETKTQKVP HYQMSFEATE 120
121 LEKNKPYEFW VTASTTIGEG QQSKSIVAMP SDQVPAKIAS FDDTFTATFK EDAKMPCLAV 180
181 GAPQPEITWK IKGVEFSAND RMRVLPDGSL LIKSVNRQDA GDYSCHAENS IAKDSITHKL 240
241 IVLAPPQSPH VTLSATTTDA LTVKLKPHEG DTAPLHGYTL HYKPEFGEWE TSEVSVDSQK 300
301 HNIEGLLCGS RYQVYATGFN NIGAGEASDI LNTRTKGQKP KLPEKPRFIE VSSNSVSLHF 360
361 KAWKDGGCPM SHFVVESKKR DQIEWNQISN NVKPDNNYVV LDLEPATWYN LRITAHNSAG 420
421 FTVAEYDFAT LTVTGGTIAP SRDLPEL
|
| Detection Method: | |
| Confidence: | 21.0 |
| Match: | 2ec8A |
| Description: | No description for 2ec8A was found. |
|
Region A: Residues: [1606-1806] |
1 11 21 31 41 51
| | | | | |
1 SAEDTIRIIL SNLNLVVPVV AALLVIIIAI IVICILRSKG NHHKDDVVYN QTMGPGATLD 60
61 KRRPDLRDEL GYIAPPNRKL PPVPGSNYNT CDRIKRGRGG LRSNHSTWDP RRNPNLYEEL 120
121 KAPPVPMHGN HYGHAHGNAE CHYRHPGMED EICPYATFHL LGFREEMDPT KAMNFQTFPH 180
181 QNGHAGPVPG HAGTMLPPGH P
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1807-2017] |
1 11 21 31 41 51
| | | | | |
1 GHVHSRSGSQ SMPRANRYQR KNSQGGQSSI YTPAPEYDDP ANCAEEDQYR RYTRVNSQGG 60
61 SLYSGPGPEY DDPANCAPEE DQYGSQYGGP YGQPYDHYGS RGSMGRRSIG SARNPGNGSP 120
121 EPPPPPPRNH DMSNSSFNDS KESNEISEAE CDRDHGPRGN YGAVKRSPQP KDQRTTEEMR 180
181 KLIERNETGP KQLQLQQANG AGFTAYDTMA V
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
