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View Structure Prediction Details

Protein: Dscam-PAT
Organism: Drosophila melanogaster
Length: 2018 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Dscam-PAT.

Description E-value Query
Range		 Subject
Range
Dscam-PAE - The gene Down syndrome cell adhesion molecule is referred to in FlyBase by the symbol Dmel\Dscam (CG...
 1532.0 [0..3] [2018..3]

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Predicted Domain #1
Region A:
Residues: [1-141] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNMPNERLKW LMLFAAVALI ACGSQTLAAN PPDADQKGPV FLKEPTNRID FSNSTGAEIE  60
   61 CKASGNPMPE IIWIRSDGTA VGDVPGLRQI SSDGKLVFPP FRAEDYRQEV HAQVYACLAR 120
  121 NQFGSIISRD VHVRAVVSQF Y

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 79.522879
Match: 2v5sA
Description: No description for 2v5sA was found.

Predicted Domain #2
Region A:
Residues: [142-244] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ITEAENEYVI KGNAAVVKCK IPSFVADFVQ VEAWVDEEGM ELWRNNATDA YDGKYLVLPS  60
   61 GELHIREVGP EDGYKSYQCR TKHRLTGETR LSATKGRLVI TEP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.39794
Match: 2ec8A
Description: No description for 2ec8A was found.

Predicted Domain #3
Region A:
Residues: [245-916] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IGSVAPTISG DRLQEQTRKL GHSFSILCQG QAYPHPVFRW YKFIEGTTRK QAVVLNDRVK  60
   61 QVSGTLIIKD AVVEDSGKYL CVVNNSVGGE SVETVLTVTA PLSAKIDPPT QTVDFGRPAV 120
  121 FTCQYTGNPI KTVSWMKDGK AIGHSEPVLR IESVKKEDKG MYQCFVRNDQ ESAEASAELK 180
  181 LGGRFDPPVI RQAFQEETME PGPSVFLKCV AGGNPTPEIS WELDGKKIAN NDRYQVGQYV 240
  241 TVNGDVVSYL NITSVHANDG GLYKCIAKSK VGVAEHSAKL NVYGLPYIRQ MEKKAIVAGE 300
  301 TLIVTCPVAG YPIDSIVWER DNRALPINRK QKVFPNGTLI IENVERNSDQ ATYTCVAKNQ 360
  361 EGYSARGSLE VQVMAPPKLA PFDFGDSPAN FEDSVSVSCL VSSGDLPIDI EWLFNGESIS 420
  421 YASGIAVLRG GKRTSVLTID SVHAGHAGNY SCKAKNKAAS SEYSAALIVN VPPRWILEPT 480
  481 DKAFAQGSDA KVECKADGFP KPQVTWKKAV GDTPGEYKDL KKSDNIRVEE GTLHVDNIQK 540
  541 TNEGYYLCEA INGIGSGLSA VIMISVQAPP EFTEKLRNQT ARRGEPAVLQ CEAKGEKPIG 600
  601 ILWNMNNMRL DPKNDNRYTI REEILSTGVM SSLSIKRTER SDSALFTCVA TNAFGSDDAS 660
  661 INMIVQEVPE MP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 59.0
Match: 1e07A
Description: Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [917-1116] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YALKVLDKSG RSVQLSWAQP YDGNSPLDRY IIEFKRSRAS WSEIDRVIVP GHTTEAQVQK  60
   61 LSPATTYNIR IVAENAIGTS QSSEAVTIIT AEEAPSGKPQ NIKVEPVNQT TMRVTWKPPP 120
  121 RTEWNGEILG YYVGYKLSNT NSSYVFETIN FITEEGKEHN LELQNLRVYT QYSVVIQAFN 180
  181 KIGAGPLSEE EKQFTAEGTP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.0
Match: 1cfbA
Description: CRYSTAL STRUCTURE OF TANDEM TYPE III FIBRONECTIN DOMAINS FROM DROSOPHILA NEUROGLIAN AT 2.0 ANGSTROMS
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [1117-1217] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQPPSDTACT TLTSQTIRVG WVSPPLESAN GVIKTYKVVY APSDEWYDET KRHYKKTASS  60
   61 DTVLHGLKKY TNYTMQVLAT TAGGDGVRSV PIHCQTEPDV P

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.0
Match: 1x5hA
Description: The solution structure of the third fibronectin type III domain of human Neogenin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
telethonin binding 5.81747667416248 bayes_pls_golite062009
structural constituent of muscle 5.71979489668015 bayes_pls_golite062009
transmembrane receptor activity 4.81256300373074 bayes_pls_golite062009
ankyrin binding 4.69755754047169 bayes_pls_golite062009
receptor activity 4.66147271961356 bayes_pls_golite062009
alpha-actinin binding 4.57951951779666 bayes_pls_golite062009
actinin binding 4.57900103206288 bayes_pls_golite062009
cytokine binding 4.43581512268554 bayes_pls_golite062009
cytokine receptor activity 4.08668869714207 bayes_pls_golite062009
growth factor binding 4.06808996928726 bayes_pls_golite062009
molecular transducer activity 3.69234048247377 bayes_pls_golite062009
signal transducer activity 3.69234048247377 bayes_pls_golite062009
protein binding 3.24522318184038 bayes_pls_golite062009
binding 3.12471204223368 bayes_pls_golite062009
cell adhesion molecule binding 2.32179186005318 bayes_pls_golite062009
peptide hormone binding 2.12033076929638 bayes_pls_golite062009
axon guidance receptor activity 2.01367445237355 bayes_pls_golite062009
prolactin receptor activity 1.9556649101819 bayes_pls_golite062009
cytoskeletal protein binding 1.85720106085239 bayes_pls_golite062009
interleukin-2 binding 1.67132604890013 bayes_pls_golite062009
myosin light chain kinase activity 1.49217960276915 bayes_pls_golite062009
protein kinase activity 1.42856560840953 bayes_pls_golite062009
nucleic acid binding 1.32813363771214 bayes_pls_golite062009
receptor binding 1.31676259534833 bayes_pls_golite062009
transcription regulator activity 1.31663344632755 bayes_pls_golite062009
actin binding 1.21472460452555 bayes_pls_golite062009
DNA binding 1.2006039770643 bayes_pls_golite062009
growth hormone receptor activity 1.15929762138929 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.15899955607967 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.12142142875217 bayes_pls_golite062009
kinase activity 1.11027658115625 bayes_pls_golite062009
ciliary neurotrophic factor receptor activity 1.07748328484506 bayes_pls_golite062009
glycosaminoglycan binding 0.99058387466784 bayes_pls_golite062009
structural molecule activity 0.94240190391222 bayes_pls_golite062009
peptide binding 0.92031154055894 bayes_pls_golite062009
interleukin-6 receptor activity 0.888638861691021 bayes_pls_golite062009
interleukin-6 binding 0.888638861691021 bayes_pls_golite062009
protein dimerization activity 0.86564366658585 bayes_pls_golite062009
cell surface binding 0.792329562040096 bayes_pls_golite062009
heparin binding 0.7054081997714 bayes_pls_golite062009
protein serine/threonine kinase activity 0.703490254739121 bayes_pls_golite062009
collagen binding 0.688581536921572 bayes_pls_golite062009
kinase binding 0.65927255037265 bayes_pls_golite062009
oncostatin-M receptor activity 0.628488391922279 bayes_pls_golite062009
leukemia inhibitory factor receptor activity 0.628488391922279 bayes_pls_golite062009
enzyme binding 0.60195860585095 bayes_pls_golite062009
identical protein binding 0.564711394496051 bayes_pls_golite062009
transcription factor activity 0.557290274937694 bayes_pls_golite062009
transmembrane receptor protein tyrosine kinase activity 0.554350228628563 bayes_pls_golite062009
hormone binding 0.49524185948356 bayes_pls_golite062009
transmembrane receptor protein kinase activity 0.46168925186147 bayes_pls_golite062009
transferase activity 0.432850266451294 bayes_pls_golite062009
polysaccharide binding 0.4326581122899 bayes_pls_golite062009
structural constituent of cytoskeleton 0.40600177052491 bayes_pls_golite062009
protein kinase binding 0.405060010394646 bayes_pls_golite062009
interleukin-7 binding 0.301052531308189 bayes_pls_golite062009
pattern binding 0.30071837231983 bayes_pls_golite062009
protein heterodimerization activity 0.1430595594485 bayes_pls_golite062009
transcription activator activity 0.135753557343301 bayes_pls_golite062009
actin filament binding 0.135484838710405 bayes_pls_golite062009
protein homodimerization activity 0.116391819218123 bayes_pls_golite062009
interleukin-2 receptor activity 0.115337814289139 bayes_pls_golite062009
integrin binding 0.0873424694168858 bayes_pls_golite062009
transcription factor binding 0.075900818564989 bayes_pls_golite062009

Predicted Domain #6
Region A:
Residues: [1218-1318] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EAPTDVKALV MGNAAILVSW RPPAQPNGII TQYTVYSKAE GAETETKTQK VPHYQMSFEA  60
   61 TELEKNKPYE FWVTASTTIG EGQQSKSIVA MPSDQVPAKI A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.39794
Match: 1wfnA
Description: The fourth FN3 domain of human sidekick-2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
telethonin binding 5.81747667416248 bayes_pls_golite062009
structural constituent of muscle 5.71979489668015 bayes_pls_golite062009
transmembrane receptor activity 4.81256300373074 bayes_pls_golite062009
ankyrin binding 4.69755754047169 bayes_pls_golite062009
receptor activity 4.66147271961356 bayes_pls_golite062009
alpha-actinin binding 4.57951951779666 bayes_pls_golite062009
actinin binding 4.57900103206288 bayes_pls_golite062009
cytokine binding 4.43581512268554 bayes_pls_golite062009
cytokine receptor activity 4.08668869714207 bayes_pls_golite062009
growth factor binding 4.06808996928726 bayes_pls_golite062009
molecular transducer activity 3.69234048247377 bayes_pls_golite062009
signal transducer activity 3.69234048247377 bayes_pls_golite062009
protein binding 3.24522318184038 bayes_pls_golite062009
binding 3.12471204223368 bayes_pls_golite062009
cell adhesion molecule binding 2.32179186005318 bayes_pls_golite062009
peptide hormone binding 2.12033076929638 bayes_pls_golite062009
axon guidance receptor activity 2.01367445237355 bayes_pls_golite062009
prolactin receptor activity 1.9556649101819 bayes_pls_golite062009
cytoskeletal protein binding 1.85720106085239 bayes_pls_golite062009
interleukin-2 binding 1.67132604890013 bayes_pls_golite062009
myosin light chain kinase activity 1.49217960276915 bayes_pls_golite062009
protein kinase activity 1.42856560840953 bayes_pls_golite062009
nucleic acid binding 1.32813363771214 bayes_pls_golite062009
receptor binding 1.31676259534833 bayes_pls_golite062009
transcription regulator activity 1.31663344632755 bayes_pls_golite062009
actin binding 1.21472460452555 bayes_pls_golite062009
DNA binding 1.2006039770643 bayes_pls_golite062009
growth hormone receptor activity 1.15929762138929 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.15899955607967 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.12142142875217 bayes_pls_golite062009
kinase activity 1.11027658115625 bayes_pls_golite062009
ciliary neurotrophic factor receptor activity 1.07748328484506 bayes_pls_golite062009
glycosaminoglycan binding 0.99058387466784 bayes_pls_golite062009
structural molecule activity 0.94240190391222 bayes_pls_golite062009
peptide binding 0.92031154055894 bayes_pls_golite062009
interleukin-6 receptor activity 0.888638861691021 bayes_pls_golite062009
interleukin-6 binding 0.888638861691021 bayes_pls_golite062009
protein dimerization activity 0.86564366658585 bayes_pls_golite062009
cell surface binding 0.792329562040096 bayes_pls_golite062009
heparin binding 0.7054081997714 bayes_pls_golite062009
protein serine/threonine kinase activity 0.703490254739121 bayes_pls_golite062009
collagen binding 0.688581536921572 bayes_pls_golite062009
kinase binding 0.65927255037265 bayes_pls_golite062009
oncostatin-M receptor activity 0.628488391922279 bayes_pls_golite062009
leukemia inhibitory factor receptor activity 0.628488391922279 bayes_pls_golite062009
enzyme binding 0.60195860585095 bayes_pls_golite062009
identical protein binding 0.564711394496051 bayes_pls_golite062009
transcription factor activity 0.557290274937694 bayes_pls_golite062009
transmembrane receptor protein tyrosine kinase activity 0.554350228628563 bayes_pls_golite062009
hormone binding 0.49524185948356 bayes_pls_golite062009
transmembrane receptor protein kinase activity 0.46168925186147 bayes_pls_golite062009
transferase activity 0.432850266451294 bayes_pls_golite062009
polysaccharide binding 0.4326581122899 bayes_pls_golite062009
structural constituent of cytoskeleton 0.40600177052491 bayes_pls_golite062009
protein kinase binding 0.405060010394646 bayes_pls_golite062009
interleukin-7 binding 0.301052531308189 bayes_pls_golite062009
pattern binding 0.30071837231983 bayes_pls_golite062009
protein heterodimerization activity 0.1430595594485 bayes_pls_golite062009
transcription activator activity 0.135753557343301 bayes_pls_golite062009
actin filament binding 0.135484838710405 bayes_pls_golite062009
protein homodimerization activity 0.116391819218123 bayes_pls_golite062009
interleukin-2 receptor activity 0.115337814289139 bayes_pls_golite062009
integrin binding 0.0873424694168858 bayes_pls_golite062009
transcription factor binding 0.075900818564989 bayes_pls_golite062009

Predicted Domain #7
Region A:
Residues: [1319-1486] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFDDTFTATF KEDAKMPCLA VGAPQPEITW KIKGVEFSAN DRMRVLPDGS LLIKSVNRQD  60
   61 AGDYSCHAEN SIAKDSITHK LIVLAPPQSP HVTLSATTTD ALTVKLKPHE GDTAPLHGYT 120
  121 LHYKPEFGEW ETSEVSVDSQ KHNIEGLLCG SRYQVYATGF NNIGAGEA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.0
Match: 2nziA
Description: No description for 2nziA was found.

Predicted Domain #8
Region A:
Residues: [1487-1596] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDILNTRTKG QKPKLPEKPR FIEVSSNSVS LHFKAWKDGG CPMSHFVVES KKRDQIEWNQ  60
   61 ISNNVKPDNN YVVLDLEPAT WYNLRITAHN SAGFTVAEYD FATLTVTGGT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.09691
Match: 1fnhA
Description: Fibronectin, different Fn3 modules
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
telethonin binding 5.81747667416248 bayes_pls_golite062009
structural constituent of muscle 5.71979489668015 bayes_pls_golite062009
transmembrane receptor activity 4.81256300373074 bayes_pls_golite062009
ankyrin binding 4.69755754047169 bayes_pls_golite062009
receptor activity 4.66147271961356 bayes_pls_golite062009
alpha-actinin binding 4.57951951779666 bayes_pls_golite062009
actinin binding 4.57900103206288 bayes_pls_golite062009
cytokine binding 4.43581512268554 bayes_pls_golite062009
cytokine receptor activity 4.08668869714207 bayes_pls_golite062009
growth factor binding 4.06808996928726 bayes_pls_golite062009
molecular transducer activity 3.69234048247377 bayes_pls_golite062009
signal transducer activity 3.69234048247377 bayes_pls_golite062009
protein binding 3.24522318184038 bayes_pls_golite062009
binding 3.12471204223368 bayes_pls_golite062009
cell adhesion molecule binding 2.32179186005318 bayes_pls_golite062009
peptide hormone binding 2.12033076929638 bayes_pls_golite062009
axon guidance receptor activity 2.01367445237355 bayes_pls_golite062009
prolactin receptor activity 1.9556649101819 bayes_pls_golite062009
cytoskeletal protein binding 1.85720106085239 bayes_pls_golite062009
interleukin-2 binding 1.67132604890013 bayes_pls_golite062009
myosin light chain kinase activity 1.49217960276915 bayes_pls_golite062009
protein kinase activity 1.42856560840953 bayes_pls_golite062009
nucleic acid binding 1.32813363771214 bayes_pls_golite062009
receptor binding 1.31676259534833 bayes_pls_golite062009
transcription regulator activity 1.31663344632755 bayes_pls_golite062009
actin binding 1.21472460452555 bayes_pls_golite062009
DNA binding 1.2006039770643 bayes_pls_golite062009
growth hormone receptor activity 1.15929762138929 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.15899955607967 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.12142142875217 bayes_pls_golite062009
kinase activity 1.11027658115625 bayes_pls_golite062009
ciliary neurotrophic factor receptor activity 1.07748328484506 bayes_pls_golite062009
glycosaminoglycan binding 0.99058387466784 bayes_pls_golite062009
structural molecule activity 0.94240190391222 bayes_pls_golite062009
peptide binding 0.92031154055894 bayes_pls_golite062009
interleukin-6 receptor activity 0.888638861691021 bayes_pls_golite062009
interleukin-6 binding 0.888638861691021 bayes_pls_golite062009
protein dimerization activity 0.86564366658585 bayes_pls_golite062009
cell surface binding 0.792329562040096 bayes_pls_golite062009
heparin binding 0.7054081997714 bayes_pls_golite062009
protein serine/threonine kinase activity 0.703490254739121 bayes_pls_golite062009
collagen binding 0.688581536921572 bayes_pls_golite062009
kinase binding 0.65927255037265 bayes_pls_golite062009
oncostatin-M receptor activity 0.628488391922279 bayes_pls_golite062009
leukemia inhibitory factor receptor activity 0.628488391922279 bayes_pls_golite062009
enzyme binding 0.60195860585095 bayes_pls_golite062009
identical protein binding 0.564711394496051 bayes_pls_golite062009
transcription factor activity 0.557290274937694 bayes_pls_golite062009
transmembrane receptor protein tyrosine kinase activity 0.554350228628563 bayes_pls_golite062009
hormone binding 0.49524185948356 bayes_pls_golite062009
transmembrane receptor protein kinase activity 0.46168925186147 bayes_pls_golite062009
transferase activity 0.432850266451294 bayes_pls_golite062009
polysaccharide binding 0.4326581122899 bayes_pls_golite062009
structural constituent of cytoskeleton 0.40600177052491 bayes_pls_golite062009
protein kinase binding 0.405060010394646 bayes_pls_golite062009
interleukin-7 binding 0.301052531308189 bayes_pls_golite062009
pattern binding 0.30071837231983 bayes_pls_golite062009
protein heterodimerization activity 0.1430595594485 bayes_pls_golite062009
transcription activator activity 0.135753557343301 bayes_pls_golite062009
actin filament binding 0.135484838710405 bayes_pls_golite062009
protein homodimerization activity 0.116391819218123 bayes_pls_golite062009
interleukin-2 receptor activity 0.115337814289139 bayes_pls_golite062009
integrin binding 0.0873424694168858 bayes_pls_golite062009
transcription factor binding 0.075900818564989 bayes_pls_golite062009

Predicted Domain #9
Region A:
Residues: [1597-1683] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IAPSRDLPEL SAEDTIRIIL SNLNLVVPVV AALLVIIIAI IVICILRSKG NHHKDDVVYN  60
   61 QTMGPGATLD KRRPDLRDEL GYIAPPN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.0
Match: 1wj3A
Description: Solution structure of the fourth fn3 domain of KIAA1496 protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
telethonin binding 5.81747667416248 bayes_pls_golite062009
structural constituent of muscle 5.71979489668015 bayes_pls_golite062009
transmembrane receptor activity 4.81256300373074 bayes_pls_golite062009
ankyrin binding 4.69755754047169 bayes_pls_golite062009
receptor activity 4.66147271961356 bayes_pls_golite062009
alpha-actinin binding 4.57951951779666 bayes_pls_golite062009
actinin binding 4.57900103206288 bayes_pls_golite062009
cytokine binding 4.43581512268554 bayes_pls_golite062009
cytokine receptor activity 4.08668869714207 bayes_pls_golite062009
growth factor binding 4.06808996928726 bayes_pls_golite062009
molecular transducer activity 3.69234048247377 bayes_pls_golite062009
signal transducer activity 3.69234048247377 bayes_pls_golite062009
protein binding 3.24522318184038 bayes_pls_golite062009
binding 3.12471204223368 bayes_pls_golite062009
cell adhesion molecule binding 2.32179186005318 bayes_pls_golite062009
peptide hormone binding 2.12033076929638 bayes_pls_golite062009
axon guidance receptor activity 2.01367445237355 bayes_pls_golite062009
prolactin receptor activity 1.9556649101819 bayes_pls_golite062009
cytoskeletal protein binding 1.85720106085239 bayes_pls_golite062009
interleukin-2 binding 1.67132604890013 bayes_pls_golite062009
myosin light chain kinase activity 1.49217960276915 bayes_pls_golite062009
protein kinase activity 1.42856560840953 bayes_pls_golite062009
nucleic acid binding 1.32813363771214 bayes_pls_golite062009
receptor binding 1.31676259534833 bayes_pls_golite062009
transcription regulator activity 1.31663344632755 bayes_pls_golite062009
actin binding 1.21472460452555 bayes_pls_golite062009
DNA binding 1.2006039770643 bayes_pls_golite062009
growth hormone receptor activity 1.15929762138929 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.15899955607967 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.12142142875217 bayes_pls_golite062009
kinase activity 1.11027658115625 bayes_pls_golite062009
ciliary neurotrophic factor receptor activity 1.07748328484506 bayes_pls_golite062009
glycosaminoglycan binding 0.99058387466784 bayes_pls_golite062009
structural molecule activity 0.94240190391222 bayes_pls_golite062009
peptide binding 0.92031154055894 bayes_pls_golite062009
interleukin-6 receptor activity 0.888638861691021 bayes_pls_golite062009
interleukin-6 binding 0.888638861691021 bayes_pls_golite062009
protein dimerization activity 0.86564366658585 bayes_pls_golite062009
cell surface binding 0.792329562040096 bayes_pls_golite062009
heparin binding 0.7054081997714 bayes_pls_golite062009
protein serine/threonine kinase activity 0.703490254739121 bayes_pls_golite062009
collagen binding 0.688581536921572 bayes_pls_golite062009
kinase binding 0.65927255037265 bayes_pls_golite062009
oncostatin-M receptor activity 0.628488391922279 bayes_pls_golite062009
leukemia inhibitory factor receptor activity 0.628488391922279 bayes_pls_golite062009
enzyme binding 0.60195860585095 bayes_pls_golite062009
identical protein binding 0.564711394496051 bayes_pls_golite062009
transcription factor activity 0.557290274937694 bayes_pls_golite062009
transmembrane receptor protein tyrosine kinase activity 0.554350228628563 bayes_pls_golite062009
hormone binding 0.49524185948356 bayes_pls_golite062009
transmembrane receptor protein kinase activity 0.46168925186147 bayes_pls_golite062009
transferase activity 0.432850266451294 bayes_pls_golite062009
polysaccharide binding 0.4326581122899 bayes_pls_golite062009
structural constituent of cytoskeleton 0.40600177052491 bayes_pls_golite062009
protein kinase binding 0.405060010394646 bayes_pls_golite062009
interleukin-7 binding 0.301052531308189 bayes_pls_golite062009
pattern binding 0.30071837231983 bayes_pls_golite062009
protein heterodimerization activity 0.1430595594485 bayes_pls_golite062009
transcription activator activity 0.135753557343301 bayes_pls_golite062009
actin filament binding 0.135484838710405 bayes_pls_golite062009
protein homodimerization activity 0.116391819218123 bayes_pls_golite062009
interleukin-2 receptor activity 0.115337814289139 bayes_pls_golite062009
integrin binding 0.0873424694168858 bayes_pls_golite062009
transcription factor binding 0.075900818564989 bayes_pls_golite062009

Predicted Domain #10
Region A:
Residues: [1684-1796] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKLPPVPGSN YNTCDRIKRG RGGLRSNHST WDPRRNPNLY EELKAPPVPM HGNHYGHAHG  60
   61 NAECHYRHPG MEDEICPYAT FHLLGFREEM DPTKAMNFQT FPHQNGHAGP VPG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #11
Region A:
Residues: [1797-2018] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HAGTMLPPGH PGHVHSRSGS QSMPRANRYQ RKNSQGGQSS IYTPAPEYDD PANCAEEDQY  60
   61 RRYTRVNSQG GSLYSGPGPE YDDPANCAPE EDQYGSQYGG PYGQPYDHYG SRGSMGRRSI 120
  121 GSARNPGNGS PEPPPPPPRN HDMSNSSFND SKESNEISEA ECDRDHGPRG NYGAVKRSPQ 180
  181 PKDQRTTEEM RKLIERNETG PKQLQLQQAN GAGFTAYDTM AV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle