| Protein: | Dscam-PAS |
| Organism: | Drosophila melanogaster |
| Length: | 2034 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Dscam-PAS.
| Description | E-value | Query Range |
Subject Range |
|
|
1540.0 | [0..3] | [2034..3] |
|
Region A: Residues: [1-249] |
1 11 21 31 41 51
| | | | | |
1 MNMPNERLKW LMLFAAVALI ACGSQTLAAN PPDADQKGPV FLKEPTNRID FSNSTGAEIE 60
61 CKASGNPMPE IIWIRSDGTA VGDVPGLRQI SSDGKLVFPP FRAEDYRQEV HAQVYACLAR 120
121 NQFGSIISRD VHVRAVVSQF YITEAENEYV IKGNAAVVKC KIPSFVADFV QVEAWVDEEG 180
181 MELWRNNATD AYDGKYLVLP SGELHIREVG PEDGYKSYQC RTKHRLTGET RLSATKGRLV 240
241 ITEPISSAV
|
| Detection Method: |  |
| Confidence: | 76.522879 |
| Match: | 2v5sA |
| Description: | No description for 2v5sA was found. |
|
Region A: Residues: [250-900] |
1 11 21 31 41 51
| | | | | |
1 PKVVSLAKFD MKTYSGSSTM ALLCPAQGYP VPVFRWYKFI EGTTRKQAVV LNDRVKQVSG 60
61 TLIIKDAVVE DSGKYLCVVN NSVGGESVET VLTVTAPLSA KIDPPTQTVD FGRPAVFTCQ 120
121 YTGNPIKTVS WMKDGKAIGH SEPVLRIESV KKEDKGMYQC FVRNDQESAE ASAELKLGGR 180
181 FDPPVIRQAF QEETMEPGPS VFLKCVAGGN PTPEISWELD GKKIANNDRY QVGQYVTVNG 240
241 DVVSYLNITS VHANDGGLYK CIAKSKVGVA EHSAKLNVYG LPYIRQMEKK AIVAGETLIV 300
301 TCPVAGYPID SIVWERDNRA LPINRKQKVF PNGTLIIENV ERNSDQATYT CVAKNQEGYS 360
361 ARGSLEVQVM VPPKITPFDF GDAPTNVEDS VSVMCLISNG DLPIDIEWFF NDYGISSYSG 420
421 INVVKGGKRN SMLSIDSVQA RHAGKYSCRA KNHAAAVNYT TELIVNVPPR WILEPTDKAF 480
481 AQGSDAKVEC KADGFPKPQV TWKKAVGDTP GEYKDLKKSD NIRVEEGTLH VDNIQKTNEG 540
541 YYLCEAINGI GSGLSAVIMI SVQAPPEFTE KLRNQTARRG EPAVLQCEAK GEKPIGILWN 600
601 MNNMRLDPKN DNRYTIREEI LSTGVMSSLS IKRTERSDSA LFTCVATNAF G
|
| Detection Method: | |
| Confidence: | 59.69897 |
| Match: | 1e07A |
| Description: | Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [901-1352] |
1 11 21 31 41 51
| | | | | |
1 SDDASINMIV QEVPEMPYAL KVLDKSGRSV QLSWAQPYDG NSPLDRYIIE FKRSRASWSE 60
61 IDRVIVPGHT TEAQVQKLSP ATTYNIRIVA ENAIGTSQSS EAVTIITAEE APSGKPQNIK 120
121 VEPVNQTTMR VTWKPPPRTE WNGEILGYYV GYKLSNTNSS YVFETINFIT EEGKEHNLEL 180
181 QNLRVYTQYS VVIQAFNKIG AGPLSEEEKQ FTAEGTPSQP PSDTACTTLT SQTIRVGWVS 240
241 PPLESANGVI KTYKVVYAPS DEWYDETKRH YKKTASSDTV LHGLKKYTNY TMQVLATTAG 300
301 GDGVRSVPIH CQTEPDVPEA PTDVKALVMG NAAILVSWRP PAQPNGIITQ YTVYSKAEGA 360
361 ETETKTQKVP HYQMSFEATE LEKNKPYEFW VTASTTIGEG QQSKSIVAMP SDQVPAKIAS 420
421 FDDTFTATFK EDAKMPCLAV GAPQPEITWK IK
|
| Detection Method: | |
| Confidence: | 28.522879 |
| Match: | 2v5yA |
| Description: | No description for 2v5yA was found. |
|
Region A: Residues: [1353-1487] |
1 11 21 31 41 51
| | | | | |
1 GVEFSANDRM RVLPDGSLLI KSVNRQDAGD YSCHAENSIA KDSITHKLIV LAPPQSPHVT 60
61 LSATTTDALT VKLKPHEGDT APLHGYTLHY KPEFGEWETS EVSVDSQKHN IEGLLCGSRY 120
121 QVYATGFNNI GAGEA
|
| Detection Method: | |
| Confidence: | 35.0 |
| Match: | 2nziA |
| Description: | No description for 2nziA was found. |
|
Region A: Residues: [1488-1605] |
1 11 21 31 41 51
| | | | | |
1 SDILNTRTKG QKPKLPEKPR FIEVSSNSVS LHFKAWKDGG CPMSHFVVES KKRDQIEWNQ 60
61 ISNNVKPDNN YVVLDLEPAT WYNLRITAHN SAGFTVAEYD FATLTVTGGT IAPLDDGS
|
| Detection Method: | |
| Confidence: | 11.69897 |
| Match: | 1x5kA |
| Description: | The solution structure of the sixth fibronectin type III domain of human Neogenin |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| telethonin binding | 5.81747667416248 | bayes_pls_golite062009 |
| structural constituent of muscle | 5.71979489668015 | bayes_pls_golite062009 |
| transmembrane receptor activity | 4.81256300373074 | bayes_pls_golite062009 |
| ankyrin binding | 4.69755754047169 | bayes_pls_golite062009 |
| receptor activity | 4.66147271961356 | bayes_pls_golite062009 |
| alpha-actinin binding | 4.57951951779666 | bayes_pls_golite062009 |
| actinin binding | 4.57900103206288 | bayes_pls_golite062009 |
| cytokine binding | 4.43581512268554 | bayes_pls_golite062009 |
| cytokine receptor activity | 4.08668869714207 | bayes_pls_golite062009 |
| growth factor binding | 4.06808996928726 | bayes_pls_golite062009 |
| molecular transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
| signal transducer activity | 3.69234048247377 | bayes_pls_golite062009 |
| protein binding | 3.24522318184038 | bayes_pls_golite062009 |
| binding | 3.12471204223368 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 2.32179186005318 | bayes_pls_golite062009 |
| peptide hormone binding | 2.12033076929638 | bayes_pls_golite062009 |
| axon guidance receptor activity | 2.01367445237355 | bayes_pls_golite062009 |
| prolactin receptor activity | 1.9556649101819 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.85720106085239 | bayes_pls_golite062009 |
| interleukin-2 binding | 1.67132604890013 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.49217960276915 | bayes_pls_golite062009 |
| protein kinase activity | 1.42856560840953 | bayes_pls_golite062009 |
| nucleic acid binding | 1.32813363771214 | bayes_pls_golite062009 |
| receptor binding | 1.31676259534833 | bayes_pls_golite062009 |
| transcription regulator activity | 1.31663344632755 | bayes_pls_golite062009 |
| actin binding | 1.21472460452555 | bayes_pls_golite062009 |
| DNA binding | 1.2006039770643 | bayes_pls_golite062009 |
| growth hormone receptor activity | 1.15929762138929 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.15899955607967 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.12142142875217 | bayes_pls_golite062009 |
| kinase activity | 1.11027658115625 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor activity | 1.07748328484506 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 0.99058387466784 | bayes_pls_golite062009 |
| structural molecule activity | 0.94240190391222 | bayes_pls_golite062009 |
| peptide binding | 0.92031154055894 | bayes_pls_golite062009 |
| interleukin-6 receptor activity | 0.888638861691021 | bayes_pls_golite062009 |
| interleukin-6 binding | 0.888638861691021 | bayes_pls_golite062009 |
| protein dimerization activity | 0.86564366658585 | bayes_pls_golite062009 |
| cell surface binding | 0.792329562040096 | bayes_pls_golite062009 |
| heparin binding | 0.7054081997714 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.703490254739121 | bayes_pls_golite062009 |
| collagen binding | 0.688581536921572 | bayes_pls_golite062009 |
| kinase binding | 0.65927255037265 | bayes_pls_golite062009 |
| oncostatin-M receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| leukemia inhibitory factor receptor activity | 0.628488391922279 | bayes_pls_golite062009 |
| enzyme binding | 0.60195860585095 | bayes_pls_golite062009 |
| identical protein binding | 0.564711394496051 | bayes_pls_golite062009 |
| transcription factor activity | 0.557290274937694 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 0.554350228628563 | bayes_pls_golite062009 |
| hormone binding | 0.49524185948356 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.46168925186147 | bayes_pls_golite062009 |
| transferase activity | 0.432850266451294 | bayes_pls_golite062009 |
| polysaccharide binding | 0.4326581122899 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.40600177052491 | bayes_pls_golite062009 |
| protein kinase binding | 0.405060010394646 | bayes_pls_golite062009 |
| interleukin-7 binding | 0.301052531308189 | bayes_pls_golite062009 |
| pattern binding | 0.30071837231983 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.1430595594485 | bayes_pls_golite062009 |
| transcription activator activity | 0.135753557343301 | bayes_pls_golite062009 |
| actin filament binding | 0.135484838710405 | bayes_pls_golite062009 |
| protein homodimerization activity | 0.116391819218123 | bayes_pls_golite062009 |
| interleukin-2 receptor activity | 0.115337814289139 | bayes_pls_golite062009 |
| integrin binding | 0.0873424694168858 | bayes_pls_golite062009 |
| transcription factor binding | 0.075900818564989 | bayes_pls_golite062009 |
|
Region A: Residues: [1606-1864] |
1 11 21 31 41 51
| | | | | |
1 GHGNVHTRIR LPAWMPEWLD LNFMVPLIAT VVVVAVGICV VCVALSRRRA DDMRGGQKDV 60
61 YYDVVYNQTM GPGATLDKRR PDLRDELGYI APPNRKLPPV PGSNYNTCDR IKRGRGGLRS 120
121 NHSTWDPRRN PNLYEELKAP PVPMHGNHYG HAHGNAECHY RHPGMEDEIC PYATFHLLGF 180
181 REEMDPTKAM NFQTFPHQNG HAGPVPGHAG TMLPPGHPGH VHSRSGSQSM PRANRYQRKN 240
241 SQGGQSSIYT PAPEYDDPA
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1865-2034] |
1 11 21 31 41 51
| | | | | |
1 NCAEEDQYRR YTRVNSQGGS LYSGPGPEYD DPANCAPEED QYGSQYGGPY GQPYDHYGSR 60
61 GSMGRRSIGS ARNPGNGSPE PPPPPPRNHD MSNSSFNDSK ESNEISEAEC DRDHGPRGNY 120
121 GAVKRSPQPK DQRTTEEMRK LIERNETGPK QLQLQQANGA GFTAYDTMAV
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
