YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: gi|3327040
Organism: Homo sapiens
Length: 734 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|3327040.

Description E-value Query
Range		 Subject
Range
gi|73947291 - gi|73947291|ref|XP_541354.2| PREDICTED: similar to Zinc finger protein 606 (Zinc finger protein 328)...
 0.0 [82..728] [2241..2882]
gi|76678552 - gi|76678552|ref|XP_583095.2| PREDICTED: similar to Zinc finger protein 268 (Zinc finger protein HZF3...
 0.0 [27..732] [531..1231]
gi|109125970 - gi|109125970|ref|XP_001115785.1| PREDICTED: similar to zinc finger protein 665 [Macaca mulatta]
 0.0 [236..726] [251..738]
gi|109485628, gi... - gi|109485628|ref|XP_001078438.1| PREDICTED: similar to zinc finger protein ZFP isoform 1 [Rattus nor...
 0.0 [98..733] [536..1162]

Back

Predicted Domain #1
Region A:
Residues: [1-69] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAADSTSMSY SVTLTGPGPW GFRLQGGKDF NMPLTISRIT PGSKAAQSQL SQGDLVVAID  60
   61 GVNTDTMTH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.221849
Match: 1rgwA
Description: Solution Structure of ZASP's PDZ domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytoskeletal protein binding 3.60106431937699 bayes_pls_golite062009
structural constituent of muscle 3.0482783169186 bayes_pls_golite062009
actinin binding 2.91261541242779 bayes_pls_golite062009
binding 2.6316969452405 bayes_pls_golite062009
protein binding 2.25893018754605 bayes_pls_golite062009
actin binding 2.13642404399707 bayes_pls_golite062009
transporter activity 0.782216866213126 bayes_pls_golite062009
transmembrane transporter activity 0.699604120098573 bayes_pls_golite062009
PDZ domain binding 0.53069705861477 bayes_pls_golite062009
substrate-specific transporter activity 0.434921764966531 bayes_pls_golite062009
actin filament binding 0.395248867755308 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.250590541549843 bayes_pls_golite062009
structural constituent of cytoskeleton 0.182094987832726 bayes_pls_golite062009
protein domain specific binding 0.15766709142367 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [70-157] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEAQNKIKSA SYNLSLTLQK SKRPIPISTT APPVQTPLPV IPHQKDPALD TNGSLVAPSP  60
   61 SPEARASPGT PGTPELRPTF SPAFSRPS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [158-241] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AFSSLAEASD PGPPRASLRA KTSPEGARDL LGPKALPGSS QPRQYNNPIG LYSAETLREM  60
   61 AQMYQMSLRG KASGVGLPGG SLPI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [242-299] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDLAVDSASP VYQAVIKSQN KPEDEADEWA RRSSNLQSRS FRILAQMTGT EFMQDPDE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [300-414] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EALRRSSTPI EHAPVCTSQA TTPLLPASAQ PPAAASPSAA SPPLATAAAH TAIASASTTA  60
   61 PASSPADSPR PQASSYSPAV AASSAPATHT SYSEGPAAPA PKPRVVTTAS IRPSV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [415-491] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YQPVPASTYS PSPGANYSPT PYTPSPAPAY TPSPAPAYTP SPVPTYTPSP APAYTPSPAP  60
   61 NYNPAPSVAY SGGPAEP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.14
Match: 1q1qA
Description: Crystal structure of human pregnenolone sulfotransferase (SULT2B1a) in the presence of PAP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transporter activity 2.52497552014278 bayes_pls_golite062009
transmembrane transporter activity 2.40658013079084 bayes_pls_golite062009
cytoskeletal protein binding 2.39214016658615 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.35708720741144 bayes_pls_golite062009
pyrophosphatase activity 2.28572270826306 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.2679790267601 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.26439443616623 bayes_pls_golite062009
primary active transmembrane transporter activity 2.08046022919779 bayes_pls_golite062009
motor activity 2.07772440476994 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 2.07687836248701 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 2.03985463174903 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 2.03554410262972 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 2.03501965794966 bayes_pls_golite062009
active transmembrane transporter activity 1.96755553127373 bayes_pls_golite062009
binding 1.95375255800529 bayes_pls_golite062009
ATPase activity 1.90719478261095 bayes_pls_golite062009
ATPase activity, coupled 1.89951058094584 bayes_pls_golite062009
actin binding 1.73490290591968 bayes_pls_golite062009
substrate-specific transporter activity 1.48825800569252 bayes_pls_golite062009
structural constituent of muscle 1.35085869260647 bayes_pls_golite062009
microtubule motor activity 1.27318173398333 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.17138261833001 bayes_pls_golite062009
hydrolase activity 1.00498978255976 bayes_pls_golite062009
tubulin binding 0.820284115671881 bayes_pls_golite062009
microfilament motor activity 0.789128756960111 bayes_pls_golite062009
actin filament binding 0.68421152762816 bayes_pls_golite062009
ion transmembrane transporter activity 0.637621825415179 bayes_pls_golite062009
microtubule binding 0.634383883834603 bayes_pls_golite062009
GTPase activity 0.603004420222648 bayes_pls_golite062009
purine nucleotide binding 0.509855138537351 bayes_pls_golite062009
nucleotide binding 0.503649548307811 bayes_pls_golite062009
purine ribonucleotide binding 0.49583023878914 bayes_pls_golite062009
ribonucleotide binding 0.495817032502758 bayes_pls_golite062009
cation transmembrane transporter activity 0.249266001065856 bayes_pls_golite062009
guanyl nucleotide binding 0.16639805763162 bayes_pls_golite062009
GTP binding 0.163692554293628 bayes_pls_golite062009
guanyl ribonucleotide binding 0.160665710980295 bayes_pls_golite062009
protein binding 0.102043618157662 bayes_pls_golite062009
protein transporter activity 0.0840319419284095 bayes_pls_golite062009
structural constituent of cytoskeleton 0.0197193998031486 bayes_pls_golite062009
ATP binding 0.00203463095479706 bayes_pls_golite062009

Predicted Domain #7
Region A:
Residues: [492-550] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASRPPWVTDD SFSQKFAPGK STTSISKQTL PRGGPAYTPA GPQVPPLARG TVQRAERFP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.69897
Match: 1tf6A
Description: Transcription factor IIIA, TFIIIA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.47962305876847 bayes_pls_golite062009
cytoskeletal protein binding 2.22104591928521 bayes_pls_golite062009
DNA binding 2.00908648793732 bayes_pls_golite062009
nucleic acid binding 1.98196470793823 bayes_pls_golite062009
transcription regulator activity 1.92901308597163 bayes_pls_golite062009
transcription factor activity 1.10908190809074 bayes_pls_golite062009
protein binding 0.905022998164426 bayes_pls_golite062009
tubulin binding 0.744315484113484 bayes_pls_golite062009
microtubule binding 0.576452165256057 bayes_pls_golite062009
chromatin binding 0.44494725351897 bayes_pls_golite062009
transcription activator activity 0.28378358922747 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.27673489856581 bayes_pls_golite062009
signal transducer activity 0.0590340677124848 bayes_pls_golite062009
molecular transducer activity 0.0590340677124848 bayes_pls_golite062009

Predicted Domain #8
Region A:
Residues: [551-734] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASSRTPLCGH CNNVIRGPFL VAMGRSWHPE EFTCAYCKTS LADVCFVEEQ NNVYCERCYE  60
   61 QFFAPLCAKC NTKIMGEVMH ALRQTWHTTC FVCAACKKPF GNSLFHMEDG EPYCEKDYIN 120
  121 LFSTKCHGCD FPVEAGDKFI EALGHTWHDT CFICAVCHVN LEGQPFYSKK DRPLCKKHAH 180
  181 TINL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.522879
Match: 2i13A
Description: No description for 2i13A was found.
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle