| Protein: | MYLK2 |
| Organism: | Homo sapiens |
| Length: | 596 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MYLK2.
| Description | E-value | Query Range |
Subject Range |
|
|
8.0E-97 | [1..596] | [1..608] |
|
|
3.0E-95 | [1..596] | [95..693] |
|
|
4.0E-93 | [1..596] | [1..613] |
|
|
1.0E-91 | [1..596] | [1..610] |
|
|
2.0E-91 | [27..553] | [10..537] |
|
Region A: Residues: [1-264] |
1 11 21 31 41 51
| | | | | |
1 MATENGAVEL GIQNPSTDKA PKGPTGERPL AAGKDPGPPD PKKAPDPPTL KKDAKAPASE 60
61 KGDGTLAQPS TSSQGPKGEG DRGGGPAEGS AGPPAALPQQ TATPETSVKK PKAEQGASGS 120
121 QDPGKPRVGK KAAEGQAAAR RGSPAFLHSP SCPAIISSSE KLLAKKPPSE ASELTFEGVP 180
181 MTHSPTDPRP AKAEEGKNIL AESQKEVGEK TPGQAGQAKM QGDTSRGIEF QAVPSEKSEV 240
241 GQALCLTARE EDCFQILDDC PPPP
|
| Detection Method: |  |
| Confidence: | 0.993 |
| Match: | 2j63A |
| Description: | No description for 2j63A was found. |
|
Region A: Residues: [265-596] |
1 11 21 31 41 51
| | | | | |
1 APFPHRMVEL RTGNVSSEFS MNSKEALGGG KFGAVCTCME KATGLKLAAK VIKKQTPKDK 60
61 EMVLLEIEVM NQLNHRNLIQ LYAAIETPHE IVLFMEYIEG GELFERIVDE DYHLTEVDTM 120
121 VFVRQICDGI LFMHKMRVLH LDLKPENILC VNTTGHLVKI IDFGLARRYN PNEKLKVNFG 180
181 TPEFLSPEVV NYDQISDKTD MWSMGVITYM LLSGLSPFLG DDDTETLNNV LSGNWYFDEE 240
241 TFEAVSDEAK DFVSNLIVKD QRARMNAAQC LAHPWLNNLA EKAKRCNRRL KSQILLKKYL 300
301 MKRRWKKNFI AVSAANRFKK ISSSGALMAL GV
|
| Detection Method: | |
| Confidence: | 75.0 |
| Match: | 1kobA |
| Description: | Twitchin, kinase domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| calmodulin-dependent protein kinase activity | 4.31938467136214 | bayes_pls_golite062009 |
| structural constituent of muscle | 3.98353882991253 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| telethonin binding | 2.51746361040969 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.12615078788254 | bayes_pls_golite062009 |
| actin-dependent ATPase activity | 2.04489973303783 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| actin binding | 1.87817875565699 | bayes_pls_golite062009 |
| molecular transducer activity | 1.79921740914853 | bayes_pls_golite062009 |
| signal transducer activity | 1.79921740914853 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| alpha-actinin binding | 1.6355769981222 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| myosin light chain kinase activity | 1.61984575672509 | bayes_pls_golite062009 |
| transcription regulator activity | 1.56748951434625 | bayes_pls_golite062009 |
| nucleic acid binding | 1.46547714006072 | bayes_pls_golite062009 |
| tubulin binding | 1.43455979766538 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 1.42275431028856 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 1.3898059094397 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.38496328649031 | bayes_pls_golite062009 |
| DNA binding | 1.35333135345112 | bayes_pls_golite062009 |
| receptor signaling protein activity | 1.27291233344322 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| microtubule binding | 1.13517379795269 | bayes_pls_golite062009 |
| transcription factor activity | 1.10928254946881 | bayes_pls_golite062009 |
| transcription activator activity | 0.997272622653026 | bayes_pls_golite062009 |
| MAP kinase activity | 0.81943579965027 | bayes_pls_golite062009 |
| actin filament binding | 0.794152600084 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.612883428421652 | bayes_pls_golite062009 |
| transporter activity | 0.595111702412257 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.499492353295369 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| G-protein coupled receptor kinase activity | 0.44436850993013 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.41384976209545 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.401250804041384 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| myosin light chain binding | 0.377312539693791 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| gamma-tubulin binding | 0.242410242748222 | bayes_pls_golite062009 |
| PTB domain binding | 0.236511077131561 | bayes_pls_golite062009 |
| axon guidance receptor activity | 0.142283017089229 | bayes_pls_golite062009 |
| ephrin receptor activity | 0.136524075351929 | bayes_pls_golite062009 |
| protein complex binding | 0.132247221889251 | bayes_pls_golite062009 |
| amine binding | 0.118831303812828 | bayes_pls_golite062009 |
| receptor binding | 0.102598082825226 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.0922946791401962 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.0556163711947139 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.00652065412910241 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.0040394359628233 | bayes_pls_golite062009 |
