| Protein: | TRPC6 |
| Organism: | Homo sapiens |
| Length: | 931 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TRPC6.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..931] | [1..931] |
|
|
0.0 | [1..931] | [168..1099] |
|
|
0.0 | [1..931] | [1..930] |
|
|
0.0 | [1..931] | [1..930] |
|
|
0.0 | [40..931] | [2..893] |
|
|
0.0 | [74..921] | [240..1066] |
|
Region A: Residues: [1-284] |
1 11 21 31 41 51
| | | | | |
1 MSQSPAFGPR RGSSPRGAAG AAARRNESQD YLLMDSELGE DGCPQAPLPC YGYYPCFRGS 60
61 DNRLAHRRQT VLREKGRRLA NRGPAYMFSD RSTSLSIEEE RFLDAAEYGN IPVVRKMLEE 120
121 CHSLNVNCVD YMGQNALQLA VANEHLEITE LLLKKENLSR VGDALLLAIS KGYVRIVEAI 180
181 LSHPAFAEGK RLATSPSQSE LQQDDFYAYD EDGTRFSHDV TPIILAAHCQ EYEIVHTLLR 240
241 KGARIERPHD YFCKCNDCNQ KQKHDSFSHS RSRINAYKGL ASPA
|
| Detection Method: |  |
| Confidence: | 45.045757 |
| Match: | 1n11A |
| Description: | Ankyrin-R |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| metal ion transmembrane transporter activity | 3.06689459321273 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.89029061890648 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 2.66479899929908 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.59441577402651 | bayes_pls_golite062009 |
| calcium channel activity | 2.42383730626707 | bayes_pls_golite062009 |
| binding | 2.41068257517762 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 2.39688396372487 | bayes_pls_golite062009 |
| channel activity | 2.39688396372487 | bayes_pls_golite062009 |
| cation channel activity | 2.37772481426745 | bayes_pls_golite062009 |
| ion channel activity | 2.36752848265558 | bayes_pls_golite062009 |
| substrate-specific channel activity | 2.26531840012081 | bayes_pls_golite062009 |
| gated channel activity | 1.75472864911207 | bayes_pls_golite062009 |
| structural constituent of muscle | 1.64895183402675 | bayes_pls_golite062009 |
| protein binding | 1.54890102798695 | bayes_pls_golite062009 |
| signal transducer activity | 1.50673806965616 | bayes_pls_golite062009 |
| molecular transducer activity | 1.50673806965616 | bayes_pls_golite062009 |
| transporter activity | 1.19000052859754 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.02570255606772 | bayes_pls_golite062009 |
| receptor activity | 0.872395596733881 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.835937200249181 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.684449236640306 | bayes_pls_golite062009 |
| mechanically-gated ion channel activity | 0.645199153849127 | bayes_pls_golite062009 |
| mechanically gated channel activity | 0.645199153849127 | bayes_pls_golite062009 |
| transcription regulator activity | 0.425387186237426 | bayes_pls_golite062009 |
| nucleic acid binding | 0.025521113335145 | bayes_pls_golite062009 |
| transcription factor binding | 4.19781566800115E-4 | bayes_pls_golite062009 |
|
Region A: Residues: [285-428] |
1 11 21 31 41 51
| | | | | |
1 YLSLSSEDPV MTALELSNEL AVLANIEKEF KNDYKKLSMQ CKDFVVGLLD LCRNTEEVEA 60
61 ILNGDVETLQ SGDHGRPNLS RLKLAIKYEV KKFVAHPNCQ QQLLSIWYEN LSGLRQQTMA 120
121 VKFLVVLAVA IGLPFLALIY WFAP
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [429-754] |
1 11 21 31 41 51
| | | | | |
1 CSKMGKIMRG PFMKFVAHAA SFTIFLGLLV MNAADRFEGT KLLPNETSTD NAKQLFRMKT 60
61 SCFSWMEMLI ISWVIGMIWA ECKEIWTQGP KEYLFELWNM LDFGMLAIFA ASFIARFMAF 120
121 WHASKAQSII DANDTLKDLT KVTLGDNVKY YNLARIKWDP SDPQIISEGL YAIAVVLSFS 180
181 RIAYILPANE SFGPLQISLG RTVKDIFKFM VIFIMVFVAF MIGMFNLYSY YIGAKQNEAF 240
241 TTVEESFKTL FWAIFGLSEV KSVVINYNHK FIENIGYVLY GVYNVTMVIV LLNMLIAMIN 300
301 SSFQEIEDDA DVEWKFARAK LWFSYF
|
| Detection Method: | |
| Confidence: | 16.39794 |
| Match: | 2a79B |
| Description: | Mammalian Shaker Kv1.2 potassium channel- beta subunit complex |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [755-931] |
1 11 21 31 41 51
| | | | | |
1 EEGRTLPVPF NLVPSPKSLF YLLLKLKKWI SELFQGHKKG FQEDAEMNKI NEEKKLGILG 60
61 SHEDLSKLSL DKKQVGHNKQ PSIRSSEDFH LNSFNNPPRQ YQKIMKRLIK RYVLQAQIDK 120
121 ESDEVNEGEL KEIKQDISSL RYELLEEKSQ NTEDLAELIR ELGEKLSMEP NQEETNR
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
